237538

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PanAT/DUF4065(antitoxin)
Location 282515..283470 Replicon chromosome
Accession NZ_CP093015
Organism Pseudomonas aeruginosa strain H16

Toxin (Protein)


Gene name panT Uniprot ID -
Locus tag MMZ76_RS01305 Protein ID WP_170868726.1
Coordinates 283144..283470 (+) Length 109 a.a.

Antitoxin (Protein)


Gene name panA Uniprot ID -
Locus tag MMZ76_RS01300 Protein ID WP_023107584.1
Coordinates 282515..283072 (+) Length 186 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MMZ76_RS01275 (MMZ76_01275) 277572..277859 - 288 WP_031686294.1 hypothetical protein -
MMZ76_RS01280 (MMZ76_01280) 277951..278427 - 477 WP_003118626.1 MarR family transcriptional regulator -
MMZ76_RS01285 (MMZ76_01285) 278468..279958 - 1491 WP_094954595.1 UbiD family decarboxylase HudA -
MMZ76_RS01290 (MMZ76_01290) 280092..280778 - 687 WP_003106170.1 YoaK family protein -
MMZ76_RS01295 (MMZ76_01295) 280942..281874 - 933 WP_042930551.1 hypothetical protein -
MMZ76_RS01300 (MMZ76_01300) 282515..283072 + 558 WP_023107584.1 Panacea domain-containing protein Antitoxin
MMZ76_RS01305 (MMZ76_01305) 283144..283470 + 327 WP_170868726.1 hypothetical protein Toxin
MMZ76_RS01315 (MMZ76_01315) 284912..286354 - 1443 WP_003133043.1 DUF2875 family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Antitoxin SocA-like, Panacea domain

(28-138)


Sequences

Toxin        


Download         Length: 109 a.a.        Molecular weight: 12366.33 Da        Isoelectric Point: 8.6957

>T237538 WP_170868726.1 NZ_CP093015:283144-283470 [Pseudomonas aeruginosa]
MNDPVYCPVLGYDAVLLVNISTVYPDKYFDQSCILKKGCHPFVLHDSWVVYREAGPFNLARLEQGVAQKSIKTHQPINAG
DFTRIRAGFDISPDVKIKVERFMRQHKI

Download         Length: 327 bp

>T237538 NZ_LR882497:364696-364998 [Mycobacterium tuberculosis variant microti]
TTGATCGCTCCCGGCGACATCGCGCCGCGCCGCGACAGTGAACACGAGCTCTACGTCGCCGTCTTGTCCAACGCGCTCCA
TCGGGCCGCGGACACCGGACGGGTGATCACCTGCCCATTCATTCCGGGCCGGGTCCCCGAGGATCTCTTGGCGATGGTGG
TGGCGGTCGAGCAACCCAACGGCACGCTGCTGCCGGAACTCGTGCAGTGGCTTCATGTTGCCGCGCTCGGTGCGCCACTC
GGCAACGCGGGCGTGGCCGCCCTACGCGAGGCTGCCTCGGTCGTGACAGCTCTGCTCTGTTAG

Antitoxin


Download         Length: 186 a.a.        Molecular weight: 21377.14 Da        Isoelectric Point: 5.8950

>AT237538 WP_023107584.1 NZ_CP093015:282515-283072 [Pseudomonas aeruginosa]
VIFSEQKVAHMAAFFLASAEGPLPHLTLIKLLYLADRESMARFDVPMSDDRAVSMPHGPVLSSTLDLIKGRLRSEVWSAW
ISPLVDHEVRLVHDVENWDDLDELSRSDRSILESVWQEFGHMTKYQLRDYTHHHIGEWHDPHGSSRDIDPKDTFMALGQS
EELAEIKARDLAERRRHGRKLSEFI

Download         Length: 558 bp

>AT237538 NZ_LR882497:364472-364699 [Mycobacterium tuberculosis variant microti]
ATGACGAAAGAGAAGATCTCCGTGACGGTGGACGCGGCCGTCCTCGCGGCGATCGACGCGGACGCCAGGGCGGCGGGTTT
GAATCGGTCGGAAATGATTGAGCAGGCACTGCGCAACGAGCACCTGCGTGTCGCTCTGCGCGATTACACGGCTAAAACCG
TACCGGCGTTGGACATCGATGCCTACGCACAGCGGGTGTACCAGGCGAACCGGGCGGCCGGAAGTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References