Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 4496592..4496953 Replicon chromosome
Accession NZ_CP092971
Organism Xanthomonas oryzae strain NJ01

Toxin (Protein)


Gene name EcnB Uniprot ID G7TLC7
Locus tag MML47_RS20540 Protein ID WP_011257368.1
Coordinates 4496592..4496726 (-) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID G7TLC8
Locus tag MML47_RS20545 Protein ID WP_011407410.1
Coordinates 4496801..4496953 (-) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MML47_RS20525 (MML47_20525) 4493609..4494553 - 945 WP_053503275.1 MBL fold metallo-hydrolase -
MML47_RS20530 (MML47_20530) 4494684..4495973 - 1290 WP_024744479.1 tryptophan--tRNA ligase -
MML47_RS20535 (MML47_20535) 4496142..4496351 - 210 WP_053503274.1 CsbD family protein -
MML47_RS20540 (MML47_20540) 4496592..4496726 - 135 WP_011257368.1 entericidin A/B family lipoprotein Toxin
MML47_RS20545 (MML47_20545) 4496801..4496953 - 153 WP_011407410.1 entericidin A/B family lipoprotein Antitoxin
MML47_RS20550 (MML47_20550) 4497061..4497984 - 924 WP_053503273.1 arginase -
MML47_RS20555 (MML47_20555) 4498308..4498526 + 219 Protein_3915 hypothetical protein -
MML47_RS20560 (MML47_20560) 4498518..4498981 + 464 Protein_3916 hypothetical protein -
MML47_RS20565 (MML47_20565) 4498978..4499519 + 542 Protein_3917 GTPase -
MML47_RS20570 (MML47_20570) 4499999..4500682 + 684 WP_024744474.1 dTMP kinase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4457.33 Da        Isoelectric Point: 10.2040

>T237427 WP_011257368.1 NZ_CP092971:c4496726-4496592 [Xanthomonas oryzae]
MKRAIVLLVLSMLSVGLLSGCNTVAGAGKDVKGAGEKVEDAARK

Download         Length: 135 bp

>T237427 NZ_LR882053:104423-104803 [Escherichia coli]
ATGAGGCATATATCACCGGAAGAACTTATTGCGCTTCATGATGCGAATATAAACCGCTACGACGGCCTGCCGGGAATGTC
TGATCCGGGTAAGGCAGAGGCCATTATCGGGAGAGTTCAGGCCAGAGTTGCCTACGAAGAGATCACCGACCTTTTCGAAG
TCTCCGCCACCTACCTGGTGGCTACAGCGAGAGGGCATATATTCAATGATGCCAATAAGCGTACCGCGCTAAACAGTGCG
CTGTTATTTCTACGCCGTAACGGGGTGCAGGTATTTGATTCACCTGAACTGGCAGACCTTACCGTAGGGGCTGCGACCGG
AGAGATATCTGTATCTTCTGTCGCCGACACGTTACGTAGATTGTATGGTTCTGCGGAGTAG

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5046.99 Da        Isoelectric Point: 8.7942

>AT237427 WP_011407410.1 NZ_CP092971:c4496953-4496801 [Xanthomonas oryzae]
MKRLLTLMVLGLFSAGVMTGCNTVAGAGKDLQGAGGKVEKTAEKCSDGKC

Download         Length: 153 bp

>AT237427 NZ_LR882053:104202-104423 [Escherichia coli]
ATGCAATCCATTAACTTCCGTACCGCGCGCGGCAACCTTTCTGAAGTGCTCAACAATGTTGAGGCCGGGGAAGAGGTTGA
AATCACCCGCAGAGGCCGTGAGCCAGCAGTAATTGTCAGCAAGGCTACTTTCGAAGCCTACAAAAAAGCGGCGCTGGATG
CTGAATTTGCATCCCTGTTTGACACCCTGGACTCCACCAACAAGGAACTGGTTAACCGATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0C5UG40

Antitoxin

Source ID Structure
AlphaFold DB A0A0C5V759

References