Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YafQ-RelB
Location 582091..582698 Replicon chromosome
Accession NZ_CP092892
Organism Agrobacterium tumefaciens strain LN-1

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag MLE07_RS02910 Protein ID WP_020811443.1
Coordinates 582091..582378 (-) Length 96 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A822V573
Locus tag MLE07_RS02915 Protein ID WP_020811442.1
Coordinates 582423..582698 (-) Length 92 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MLE07_RS02895 (MLE07_02895) 578144..580336 - 2193 WP_243016409.1 transglycosylase domain-containing protein -
MLE07_RS02900 (MLE07_02900) 580591..581070 + 480 WP_020009676.1 YcgN family cysteine cluster protein -
MLE07_RS02905 (MLE07_02905) 581239..582063 + 825 WP_003509224.1 class D beta-lactamase -
MLE07_RS02910 (MLE07_02910) 582091..582378 - 288 WP_020811443.1 type II toxin-antitoxin system YafQ family toxin Toxin
MLE07_RS02915 (MLE07_02915) 582423..582698 - 276 WP_020811442.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
MLE07_RS02920 (MLE07_02920) 582911..585490 + 2580 WP_243016411.1 heavy metal translocating P-type ATPase -
MLE07_RS02925 (MLE07_02925) 585487..585909 + 423 WP_243016412.1 Cu(I)-responsive transcriptional regulator -
MLE07_RS02930 (MLE07_02930) 585962..586162 + 201 WP_060723954.1 heavy-metal-associated domain-containing protein -
MLE07_RS02935 (MLE07_02935) 586239..586508 + 270 WP_003509217.1 type II toxin-antitoxin system ParD family antitoxin -
MLE07_RS02940 (MLE07_02940) 586498..586863 + 366 WP_112277691.1 type II toxin-antitoxin system RelE/ParE family toxin -
MLE07_RS02945 (MLE07_02945) 586860..587108 - 249 WP_162690375.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(6-95)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-85)


Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 11264.90 Da        Isoelectric Point: 6.9783

>T237332 WP_020811443.1 NZ_CP092892:c582378-582091 [Agrobacterium tumefaciens]
VLPRSSDFTRQFIKDWQRLNNSGRYDMVKLKEIMLLLIANEAPLPAQFRDHELTGEWHDHRECHVGGDFLLIYKLDEKQN
LLIFTRAGTHAELFR

Download         Length: 288 bp

>T237332 NZ_LR881938:c1269034-1268927 [Escherichia coli str. K-12 substr. MG1655]
ATGACGCTCGCGCAGTTTGCCATGACTTTCTGGCACGACCTGGCGGCACCGATCCTGGCGGGAATTATTACCGCAGCGAT
TGTCGGCTGGTGGCGTAACCGGAAGTAA

Antitoxin


Download         Length: 92 a.a.        Molecular weight: 9930.42 Da        Isoelectric Point: 8.6855

>AT237332 WP_020811442.1 NZ_CP092892:c582698-582423 [Agrobacterium tumefaciens]
MTANAYVRARIDQALKDDATAVLDSLGLTVSDVMRMMLTRIAREKALPIELTQPNAETLAAIEEARAIAAARRNRFGTAQ
ALFDALDGNKR

Download         Length: 276 bp

>AT237332 NZ_LR881938:1269081-1269147 [Escherichia coli str. K-12 substr. MG1655]
TGTCTGGTTTCAAGATTAGCCCCCGTTCTGTTGTCAGGTTTTACCTCTCAACGTGCGGGGGTTTTCT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A822V573

References