Detailed information of TA system TA237261

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): parDE/ParE-CC2985
• Location: 3800519..3801060
• Replicon: chromosome
• Accession: NZ_CP092848
• Organism: Methylobacterium organophilum strain WPA_B

Toxin (Protein)

• Gene name: parE
• Uniprot ID: -
• Locus tag: MMB17_RS17895
• Protein ID: WP_241099759.1
• Coordinates: 3800519..3800809 (-)
• Length: 97 a.a.

Antitoxin (Protein)

• Gene name: parD
• Uniprot ID: -
• Locus tag: MMB17_RS17900
• Protein ID: WP_241102230.1
• Coordinates: 3800806..3801060 (-)
• Length: 85 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
MMB17_RS17875 (MMB17_17875)	3796395..3797150	+	756	WP_241102229.1	trehalose-phosphatase	-
MMB17_RS17880 (MMB17_17880)	3797446..3799593	+	2148	WP_241099756.1	sodium-translocating pyrophosphatase	-
MMB17_RS17885 (MMB17_17885)	3799681..3799917	-	237	WP_241099757.1	hypothetical protein	-
MMB17_RS17890 (MMB17_17890)	3800015..3800500	-	486	WP_241099758.1	YaiI/YqxD family protein	-
MMB17_RS17895 (MMB17_17895)	3800519..3800809	-	291	WP_241099759.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
MMB17_RS17900 (MMB17_17900)	3800806..3801060	-	255	WP_241102230.1	type II toxin-antitoxin system ParD family antitoxin	Antitoxin
MMB17_RS17905 (MMB17_17905)	3801124..3803298	-	2175	WP_241099760.1	glycine--tRNA ligase subunit beta	-
MMB17_RS17910 (MMB17_17910)	3803363..3805270	-	1908	WP_241099761.1	PhoX family phosphatase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (3-91)

Antitoxin

• Antitoxin ParD (1-78)

Sequences

Toxin

Protein

• Length: 97 a.a.
• Molecular weight: 11143.74 Da
• Isoelectric Point: 11.4200

>T237261 WP_241099759.1 NZ_CP092848:c3800809-3800519 [Methylobacterium organophilum]
VTIRLSRRAVGDIIEIYTRGAQEYGTQHAERYGAGLRALFRLLAANPGIARRRTEFSRPVRLHPYRAHLVAYTEQEDGIL
IVRVLHNRQDWPRHLS

Nucleotide

• Length: 291 bp

>T237261 NZ_LR828253:c4698801-4698649 [Xanthomonas hortorum pv. gardneri]
ATGAAGCGACTGCTGACACTGATGGTGCTAGGCCTGTTTTCGGCTGGCGTGATGACTGGCTGCAACACCATGGCCGGCGC
CGGCAAGGACATGCAGGGCGCAGGTGAGAAGGTCGAAAAGAAGGCCGATAATTGCAGCGACGGCAAGTGCTGA

Antitoxin

Protein

• Length: 85 a.a.
• Molecular weight: 9457.57 Da
• Isoelectric Point: 4.4189

>AT237261 WP_241102230.1 NZ_CP092848:c3801060-3800806 [Methylobacterium organophilum]
MATLNLSLPEPMKEWVEAQARSGRFSDAGEYLRALIQRDRETADARAELERLVAEGFDSGVSELSMDDVLDMARREARIA
SQTR

Nucleotide

• Length: 255 bp

>AT237261 NZ_LR828253:c4698570-4698436 [Xanthomonas hortorum pv. gardneri]
ATGAAGCGTGCAATTATGCTGCTGGTGCTGTCGGTGTTTTCGGTCGGTATGCTGGCGGGTTGCAACACCGTCGCAGGTGC
TGGCAAGGACGTGCAGGGCGCTGGCGAGAAAGTGGAAGACGCTGCGCGCAAGTGA