Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/RHH(antitoxin)
Location 94347..94880 Replicon chromosome
Accession NZ_CP092845
Organism Burkholderia ambifaria strain Q53

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag MK974_RS28770 Protein ID WP_269018816.1
Coordinates 94605..94880 (+) Length 92 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag MK974_RS28765 Protein ID WP_165754271.1
Coordinates 94347..94592 (+) Length 82 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MK974_RS28740 (MK974_28700) 89580..90305 - 726 WP_269018815.1 pirin family protein -
MK974_RS28745 (MK974_28705) 90433..91317 + 885 WP_175666342.1 LysR family transcriptional regulator -
MK974_RS28750 (MK974_28710) 91521..92546 + 1026 WP_269019053.1 lysozyme inhibitor LprI family protein -
MK974_RS28755 (MK974_28715) 92818..93276 + 459 WP_269019054.1 MEKHLA domain-containing protein -
MK974_RS28760 (MK974_28720) 93544..94026 + 483 WP_165754270.1 hypothetical protein -
MK974_RS28765 (MK974_28725) 94347..94592 + 246 WP_165754271.1 type II toxin-antitoxin system ParD family antitoxin Antitoxin
MK974_RS28770 (MK974_28730) 94605..94880 + 276 WP_269018816.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
MK974_RS28775 (MK974_28735) 94912..95383 - 472 Protein_89 error-prone DNA polymerase -
MK974_RS28780 (MK974_28740) 95684..96097 + 414 WP_011660963.1 DoxX family protein -
MK974_RS28785 (MK974_28745) 96259..97203 + 945 WP_269018817.1 SDR family oxidoreductase -
MK974_RS28790 (MK974_28750) 97645..98994 + 1350 WP_269018818.1 reverse transcriptase family protein -
MK974_RS28795 (MK974_28755) 99062..99364 - 303 WP_229064489.1 hypothetical protein -
MK974_RS28800 (MK974_28760) 99363..99692 + 330 WP_006750598.1 H-NS histone family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Antitoxin ParD

(1-80)


Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 9987.05 Da        Isoelectric Point: 4.8210

>T237258 WP_269018816.1 NZ_CP092845:94605-94880 [Burkholderia ambifaria]
VADAAGEADLEDIWAHTFERWSLEQAEHYVGELASASSVSRGASGEGDRVVRATAIGATWSAPTWCSIAKRPESLDLIRV
LHQRMDVDRHL

Download         Length: 276 bp

>T237258 NZ_LR828253:3811213-3811464 [Xanthomonas hortorum pv. gardneri]
ATGGACACCATCACCTACAGCGCCGCGCGTGCCTCTCTGGCCGACACCATGGACCGTGTCGTCAATGACCACGAGCCGGT
GATCATCACGCGCAGCGGTGAGCGCGCCGTGGTCATGGTGTCGCTGGAAGATTACAAGGCCATGGAAGAGACCGCCTACC
TGTTGCGCAGCCCGAAGAGTGCGCAACGGCTGCTGGAATCCATTGCCCAGCTTGAGGCCGGTCGCGGCAAGGAACGGGAA
CTGGCTGAGTGA

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 8866.92 Da        Isoelectric Point: 5.6726

>AT237258 WP_165754271.1 NZ_CP092845:94347-94592 [Burkholderia ambifaria]
MARNTSISLGDHLTQFVDMQVASGRYGSASDVVRAGLRLLETQETELRALQEALKAGEASGEPTAFDSQAFLERMRKKHA
D

Download         Length: 246 bp

>AT237258 NZ_LR828253:3811461-3811718 [Xanthomonas hortorum pv. gardneri]
GTGATTCTGCAGTTTGCTGACAATACCTGGGAGGACTACCTCTACTGGCAACAGACCGACAAGAAGATGCTCAAACGCAT
CAACGAGTTGATCAAGGCCATTCAGCGCGATCCTTTCCAGGGCATCGGCAAACCCGAACCGTTGCGCCATGCGCTGGCGG
GCTACTGGTCACGCCGCATCAACGACGAACACCGGATTGTCTACAAGGCCGAGAACGGCATCCTGCTGATTGCTCAGGCG
CGCTACCACTACGCGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References