Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) vapBC/VapC-StbC
Location 1274204..1274843 Replicon chromosome
Accession NZ_CP092844
Organism Burkholderia ambifaria strain Q53

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag MK974_RS21685 Protein ID WP_006753827.1
Coordinates 1274427..1274843 (+) Length 139 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag MK974_RS21680 Protein ID WP_269018413.1
Coordinates 1274204..1274440 (+) Length 79 a.a.

Genomic Context


MK974_RS21665MK974_RS21675MK974_RS21680MK974_RS21685MK974_RS21690MK974_RS21695MK974_RS21700MK974_RS21710MK974_RS21715MK974_RS21725MK974_RS21670MK974_RS21705MK974_RS21720MK974_RS21730
Location: 1269707..1270576 (870 bp)
Type: Others
Protein ID: WP_011658910.1
Location: 1272754..1273956 (1203 bp)
Type: Others
Protein ID: WP_269018412.1
Location: 1274204..1274440 (237 bp)
Type: Antitoxin
Protein ID: WP_269018413.1
Location: 1274427..1274843 (417 bp)
Type: Toxin
Protein ID: WP_006753827.1
Location: 1275057..1275251 (195 bp)
Type: Others
Protein ID: WP_244098807.1
Location: 1275535..1275738 (204 bp)
Type: Others
Protein ID: WP_006751843.1
Location: 1276200..1276463 (264 bp)
Type: Others
Protein ID: WP_006751842.1
Location: 1276867..1277133 (267 bp)
Type: Others
Protein ID: Protein_1134
Location: 1277137..1277652 (516 bp)
Type: Others
Protein ID: WP_269018414.1
Location: 1278214..1278462 (249 bp)
Type: Others
Protein ID: WP_175699185.1
Location: 1271301..1272527 (1227 bp)
Type: Others
Protein ID: WP_269018411.1
Location: 1276758..1276871 (114 bp)
Type: Others
Protein ID: Protein_1133
Location: 1277663..1278076 (414 bp)
Type: Others
Protein ID: WP_269018415.1
Location: 1278486..1279649 (1164 bp)
Type: Others
Protein ID: WP_229063860.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
MK974_RS21665 (MK974_21645)1269707..1270576+870WP_011658910.1LysR substrate-binding domain-containing protein-
MK974_RS21670 (MK974_21650)1271301..1272527-1227WP_269018411.1acyltransferase-
MK974_RS21675 (MK974_21655)1272754..1273956+1203WP_269018412.1glycosyltransferase family 87 protein-
MK974_RS21680 (MK974_21660)1274204..1274440+237WP_269018413.1DNA-binding proteinAntitoxin
MK974_RS21685 (MK974_21665)1274427..1274843+417WP_006753827.1type II toxin-antitoxin system VapC family toxinToxin
MK974_RS21690 (MK974_21670)1275057..1275251+195WP_244098807.1hypothetical protein-
MK974_RS21695 (MK974_21675)1275535..1275738+204WP_006751843.1cold-shock protein-
MK974_RS21700 (MK974_21680)1276200..1276463+264WP_006751842.1translation initiation factor IF-1-
MK974_RS21705 (MK974_21685)1276758..1276871-114Protein_11334-hydroxy-2-oxovalerate aldolase-
MK974_RS21710 (MK974_21690)1276867..1277133+267Protein_1134FAD-binding protein-
MK974_RS21715 (MK974_21695)1277137..1277652+516WP_269018414.1transferase hexapeptide repeat family protein-
MK974_RS21720 (MK974_21700)1277663..1278076-414WP_269018415.1hypothetical protein-
MK974_RS21725 (MK974_21705)1278214..1278462+249WP_175699185.1hypothetical protein-
MK974_RS21730 (MK974_21710)1278486..1279649-1164WP_229063860.1MFS transporter-

Associated MGEs


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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(3-130)

Antitoxin


No domain identified.



Sequences


Toxin        


Download         Length: 139 a.a.        Molecular weight: 15295.49 Da        Isoelectric Point: 6.9900

>T237252 WP_006753827.1 NZ_CP092844:1274427-1274843 [Burkholderia ambifaria]
VFLIDTNVISEIRKGKRTNRGVRAFFRQAEADASPLYLSVVTVAELRRGVDLIRHRGDHPQASALEAWMATILSGYASNI
LPVDIETAQMWGHLRVPDPAHALDHLIAATALINDLTVVTRNVDDFARTGVRLLNPFD

Download         Length: 417 bp

>T237252 NZ_LR822061:2482914-2483021 [Staphylococcus aureus]
ATGTTCAATTTATTAATTAACATCATGACTTCAGCTTTAAGCGGCTGTCTTGTTGCGTTTTTTGCACATTGGTTACGAAC
GCGCAACAATAAAAAAGGTGACAAATAA

Antitoxin


Download         Length: 79 a.a.        Molecular weight: 8633.70 Da        Isoelectric Point: 6.4632

>AT237252 WP_269018413.1 NZ_CP092844:1274204-1274440 [Burkholderia ambifaria]
MANLLVRNVDDSIVQSLREQAAANGRSAEAEHRAILAAALGRPKRRTFAHVLMSMPDVGEDADFQRVQDSGEVRRVFD

Download         Length: 237 bp

>AT237252 NZ_LR822061:c2483098-2483038 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins


Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures


Toxin

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Source
ID
Structure
No matching records found


Antitoxin

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Source
ID
Structure
No matching records found

References