Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | pemK-mazE/MazF(toxin) |
| Location | 1510843..1511481 | Replicon | chromosome |
| Accession | NZ_CP092831 | ||
| Organism | Paenibacillus peoriae strain ZBSF16 | ||
Toxin (Protein)
| Gene name | pemK | Uniprot ID | H6CFY1 |
| Locus tag | MLD56_RS06750 | Protein ID | WP_007429335.1 |
| Coordinates | 1511131..1511481 (+) | Length | 117 a.a. |
Antitoxin (Protein)
| Gene name | mazE | Uniprot ID | H6CFY0 |
| Locus tag | MLD56_RS06745 | Protein ID | WP_007429334.1 |
| Coordinates | 1510843..1511124 (+) | Length | 94 a.a. |
Genomic Context
Location: 1507066..1507697 (632 bp)
Type: Others
Protein ID: Protein_1278
Type: Others
Protein ID: Protein_1278
Location: 1507808..1509085 (1278 bp)
Type: Others
Protein ID: WP_029516342.1
Type: Others
Protein ID: WP_029516342.1
Location: 1509355..1510551 (1197 bp)
Type: Others
Protein ID: WP_029516343.1
Type: Others
Protein ID: WP_029516343.1
Location: 1510843..1511124 (282 bp)
Type: Antitoxin
Protein ID: WP_007429334.1
Type: Antitoxin
Protein ID: WP_007429334.1
Location: 1511131..1511481 (351 bp)
Type: Toxin
Protein ID: WP_007429335.1
Type: Toxin
Protein ID: WP_007429335.1
Location: 1511661..1513883 (2223 bp)
Type: Others
Protein ID: WP_029516344.1
Type: Others
Protein ID: WP_029516344.1
Location: 1514267..1514791 (525 bp)
Type: Others
Protein ID: WP_029516345.1
Type: Others
Protein ID: WP_029516345.1
Location: 1513988..1514122 (135 bp)
Type: Others
Protein ID: WP_007429337.1
Type: Others
Protein ID: WP_007429337.1
Location: 1515181..1516056 (876 bp)
Type: Others
Protein ID: WP_029516346.1
Type: Others
Protein ID: WP_029516346.1
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Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| MLD56_RS06730 (MLD56_06730) | 1507066..1507697 | + | 632 | Protein_1278 | LysE family transporter | - |
| MLD56_RS06735 (MLD56_06735) | 1507808..1509085 | + | 1278 | WP_029516342.1 | outer membrane lipoprotein-sorting protein | - |
| MLD56_RS06740 (MLD56_06740) | 1509355..1510551 | + | 1197 | WP_029516343.1 | alanine racemase | - |
| MLD56_RS06745 (MLD56_06745) | 1510843..1511124 | + | 282 | WP_007429334.1 | ribbon-helix-helix protein, CopG family | Antitoxin |
| MLD56_RS06750 (MLD56_06750) | 1511131..1511481 | + | 351 | WP_007429335.1 | type II toxin-antitoxin system PemK/MazF family toxin | Toxin |
| MLD56_RS06755 (MLD56_06755) | 1511661..1513883 | + | 2223 | WP_029516344.1 | Tex family protein | - |
| MLD56_RS06760 (MLD56_06760) | 1513988..1514122 | - | 135 | WP_007429337.1 | cortex morphogenetic protein CmpA | - |
| MLD56_RS06765 (MLD56_06765) | 1514267..1514791 | + | 525 | WP_029516345.1 | SprT family protein | - |
| MLD56_RS06780 (MLD56_06780) | 1515181..1516056 | - | 876 | WP_029516346.1 | Cof-type HAD-IIB family hydrolase | - |
Associated MGEs
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MGE detail | Similar MGEs | Relative position | MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| No matching records found | |||||||
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 117 a.a. Molecular weight: 12822.77 Da Isoelectric Point: 5.6195
>T237242 WP_007429335.1 NZ_CP092831:1511131-1511481 [Paenibacillus peoriae]
MIVKRGDVFFADLSPVVGSEQGGVRPVLIIQNDIGNRFSPTVIVAAITAQIQKAKLPTHVEIDAATHGFDRDSVVLLEQI
RTIDKQRLTDKITHLDEETMRKVSDSLQISLGLIDF
MIVKRGDVFFADLSPVVGSEQGGVRPVLIIQNDIGNRFSPTVIVAAITAQIQKAKLPTHVEIDAATHGFDRDSVVLLEQI
RTIDKQRLTDKITHLDEETMRKVSDSLQISLGLIDF
Download Length: 351 bp
>T237242 NZ_LR822060:2785446-2785682 [Staphylococcus aureus]
ATGAATAACCGCGAACAAATCGAACAGTCCGTTATAAGTGCTAGTGCGTATAACGGCAATGACACAGAGGGATTACTAAA
AGAGATTGAAGACGTGTATAAGAAAGCACAAGCGTTTGATGAAATACTTGAGGGAATGACAAATGCTATTCAACATTCAG
TTAAAGAAGGTATTGAACTTGATGAAGCAGTAGGGATTATGGCAGGTCAAGTTGTCTATAAATATGAGGAGGAATAG
ATGAATAACCGCGAACAAATCGAACAGTCCGTTATAAGTGCTAGTGCGTATAACGGCAATGACACAGAGGGATTACTAAA
AGAGATTGAAGACGTGTATAAGAAAGCACAAGCGTTTGATGAAATACTTGAGGGAATGACAAATGCTATTCAACATTCAG
TTAAAGAAGGTATTGAACTTGATGAAGCAGTAGGGATTATGGCAGGTCAAGTTGTCTATAAATATGAGGAGGAATAG
Antitoxin
Download Length: 94 a.a. Molecular weight: 10636.25 Da Isoelectric Point: 8.5257
>AT237242 WP_007429334.1 NZ_CP092831:1510843-1511124 [Paenibacillus peoriae]
MANLQNTKRIMISLPDHLLQEVDGIVAMENSNRSEFIRQAMKLYVGERKKRYIREAMQRGYMEMAKINLTMASEAFHAEE
DANSTLGRTVSGV
MANLQNTKRIMISLPDHLLQEVDGIVAMENSNRSEFIRQAMKLYVGERKKRYIREAMQRGYMEMAKINLTMASEAFHAEE
DANSTLGRTVSGV
Download Length: 282 bp
>AT237242 NZ_LR822060:2785687-2785869 [Staphylococcus aureus]
ATGAGCATTAGTGTAGGAGACAAGGTTTTTAATCCAGAAACAAATTCAACTTTAGAAATTGTACAACTTGTTGGCGATAT
TAGAGACACGCATTACAAGTTATCTGACGGATCTATTATTAGTCTTATAGACTTTGTTGTTAAACCAATTCATTTAATCA
AGGAGGCACAGGAAAATGACTAA
ATGAGCATTAGTGTAGGAGACAAGGTTTTTAATCCAGAAACAAATTCAACTTTAGAAATTGTACAACTTGTTGGCGATAT
TAGAGACACGCATTACAAGTTATCTGACGGATCTATTATTAGTCTTATAGACTTTGTTGTTAAACCAATTCATTTAATCA
AGGAGGCACAGGAAAATGACTAA