Detailed information of TA system TA237221

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/ParE-RelB
• Location: 4431712..4432228
• Replicon: chromosome
• Accession: NZ_CP092827
• Organism: Pseudomonas sp. LS.1a

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: MKK04_RS20475
• Protein ID: WP_241105932.1
• Coordinates: 4431712..4431999 (-)
• Length: 96 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: MKK04_RS20480
• Protein ID: WP_207838200.1
• Coordinates: 4431989..4432228 (-)
• Length: 80 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
MKK04_RS20465 (MKK04_20465)	4429425..4430675	+	1251	WP_087502863.1	ribonucleotide-diphosphate reductase subunit beta	-
MKK04_RS20470 (MKK04_20470)	4430876..4431412	+	537	WP_241105931.1	Bro-N domain-containing protein	-
MKK04_RS20475 (MKK04_20475)	4431712..4431999	-	288	WP_241105932.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
MKK04_RS20480 (MKK04_20480)	4431989..4432228	-	240	WP_207838200.1	type II toxin-antitoxin system RelB/DinJ family antitoxin	Antitoxin
MKK04_RS20485 (MKK04_20485)	4432584..4433480	-	897	WP_241105933.1	LysR family transcriptional regulator	-
MKK04_RS20490 (MKK04_20490)	4433654..4435690	-	2037	WP_233688339.1	pyridoxamine 5'-phosphate oxidase family protein	-
MKK04_RS20495 (MKK04_20495)	4435718..4436347	-	630	WP_207838193.1	glutathione S-transferase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (5-77)

Antitoxin

• RelB antitoxin/Antitoxin DinJ (1-69)

Sequences

Toxin

Protein

• Length: 96 a.a.
• Molecular weight: 11288.09 Da
• Isoelectric Point: 10.0714

>T237221 WP_241105932.1 NZ_CP092827:c4431999-4431712 [Pseudomonas sp. LS.1a]
MTYSLDFDSRALKEWKKLGDTVRQQFKKKLAEVLLNPRIEANRLHSLPDCYKIKLRSSGYRLVYQVIDQEIVVFVVAVDR
RERDQAYKKAAERLE

Nucleotide

• Length: 288 bp

>T237221 NZ_LR813084:c872514-872134 [Delftia tsuruhatensis]
ATGAATCCCGTTCTGGTCGATACCTCGGTCTGGATCGATCACTTCAGGCAGGGCAATCCTCACCTGGCGCAGTTGCTGCA
GCAAGACATGGCGCTCATGCATCCCCTGGTGCTGGGTGAACTGGCTTGCGGCACGCCACCGGCACGCGCACGCACGCTCG
CGGACCTTCAGCGGCTCAAGCCTGCCCGACAGGCCAGCATGCGCGAAGTGCTGGCCTTGATAGAGCGCGAGCAACTCTTT
GGTCTGGGCTGCGGTCTGGTGGACATCACGCTCCTGGCCTCGGCACTCATGTCTTCAGGCGCCAGCCTGTGGTCGCGAGA
CAAACGCCTGCACGCGCTGGCCCAGCGGTTTGGCATTGCCTGCCGGAGCGTCTTGCCGTAG

Antitoxin

Protein

• Length: 80 a.a.
• Molecular weight: 9111.51 Da
• Isoelectric Point: 4.8411

>AT237221 WP_207838200.1 NZ_CP092827:c4432228-4431989 [Pseudomonas sp. LS.1a]
MASINIRVDDELKARAYKELERLGVTPSELMRQALQYVAERGKLPFRPVLMTEDDEDLIATVKERLASPQRVRVQLDDL

Nucleotide

• Length: 240 bp

>AT237221 NZ_LR813084:c872714-872511 [Delftia tsuruhatensis]
ATGAGAACCACGGTCACCATCGACGACGCCTTGTACGAGGAAGCGCTGGAGCTGGCGGAGCCAGAAATGGACAAGGCCGA
CCTGTTTCGCGAAGCCATCAAGACGTTCGTGAGAGTGCAGGCGGCCAAGCGTCTGGCCGCGCTGGGAGGCTCCGCACCGG
ACATGCGGGAGATTCCCCGTCGCCCACAGGGCATCGAGCCATGA