Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 3500968..3501484 Replicon chromosome
Accession NZ_CP092827
Organism Pseudomonas sp. LS.1a

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag MKK04_RS16015 Protein ID WP_241105666.1
Coordinates 3500968..3501249 (-) Length 94 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag MKK04_RS16020 Protein ID WP_063913757.1
Coordinates 3501239..3501484 (-) Length 82 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MKK04_RS15995 (MKK04_15995) 3496636..3497877 - 1242 WP_241106811.1 Zn-dependent hydrolase -
MKK04_RS16000 (MKK04_16000) 3497907..3499211 - 1305 WP_233687995.1 MFS transporter -
MKK04_RS16005 (MKK04_16005) 3499503..3500411 + 909 WP_063913754.1 LysR family transcriptional regulator -
MKK04_RS16010 (MKK04_16010) 3500500..3500895 + 396 WP_241105665.1 hypothetical protein -
MKK04_RS16015 (MKK04_16015) 3500968..3501249 - 282 WP_241105666.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
MKK04_RS16020 (MKK04_16020) 3501239..3501484 - 246 WP_063913757.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
MKK04_RS16025 (MKK04_16025) 3501638..3502744 - 1107 WP_241105667.1 alkene reductase -
MKK04_RS16030 (MKK04_16030) 3502775..3503968 - 1194 WP_241105668.1 MFS transporter -
MKK04_RS16035 (MKK04_16035) 3504351..3505268 + 918 WP_241105669.1 LysR substrate-binding domain-containing protein -
MKK04_RS16040 (MKK04_16040) 3505361..3506158 + 798 WP_207836255.1 SDR family oxidoreductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-83)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(10-74)


Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 10918.80 Da        Isoelectric Point: 10.7594

>T237217 WP_241105666.1 NZ_CP092827:c3501249-3500968 [Pseudomonas sp. LS.1a]
MTYKLEFLPSAMKEWGKLGQTVREQIKKKLAERLQSPKVQADALRDLPNHYKIKLKASGYRLVYRVEDERIVVVVVSVGK
RERSEVYRSAQKR

Download         Length: 282 bp

>T237217 NZ_LR796240:c2520518-2520210 [Treponema socranskii subsp. buccale]
GTGTATAAGGTATTACAGACAGAAACATATAAGAAATGGTTTAAAAAACTCCGTGATGAAAGAGCGAAATTCGCCATAGG
TCAAAGAATTGCAAGAATGACAGTTGGCAATTTCGGGGATTCCAAGACGGTAGGCGGTGGAGTTTTTGAGCTGAGGATAG
ATGTAGGAAAAGGCTACAGAGTTTATTTTACGAACAATGGAAAGCAGATTGTAATACTTCTTGTAGGCGGTGATAAATCA
ACACAAGATGAGGATATAAAGACCGCCAAGAAAATGGCAGGGGGTATCGATTATGGAAAAATTGACTGA

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 8779.16 Da        Isoelectric Point: 4.2103

>AT237217 WP_063913757.1 NZ_CP092827:c3501484-3501239 [Pseudomonas sp. LS.1a]
MQNIFADVAVSVSELKKNPSAVMTGAAGMPVAVLNHNRVMGYMVPAELYEAMMERLEDLELSELAKSRLGEQGVPVSLDD
L

Download         Length: 246 bp

>AT237217 NZ_LR796240:c2520226-2519933 [Treponema socranskii subsp. buccale]
ATGGAAAAATTGACTGAATTTGATATGGCAGAATATCTTGATACCGAAGAATTACAAAAAGGCTATCTTGACTATAATGC
CAAAGAGGGGACACCTGAAGATTTACTCCGTGCAATAAACGCAGTGGCAAGGGCAAGGGGAATGACAAAGACGGCAAAGG
AAGCGGGCATTACAAGAGATGGGCTTTACAAGGCACTTGCCCCCGAAGCGAACCCCGCTTTTTCAACGGTGTTTAACATT
CTCCACGCTATCGGTTATACACTCACGCCTACACCGATAGCAAAAACGATGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References