Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /RES-TIGR02293
Location 2093811..2094694 Replicon chromosome
Accession NZ_CP092827
Organism Pseudomonas sp. LS.1a

Toxin (Protein)


Gene name - Uniprot ID -
Locus tag MKK04_RS09625 Protein ID WP_063915058.1
Coordinates 2094257..2094694 (+) Length 146 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID -
Locus tag MKK04_RS09620 Protein ID WP_063915059.1
Coordinates 2093811..2094260 (+) Length 150 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MKK04_RS09600 (MKK04_09600) 2089136..2090452 - 1317 WP_207833838.1 hypothetical protein -
MKK04_RS09605 (MKK04_09605) 2090661..2091875 + 1215 WP_207833836.1 sugar transporter -
MKK04_RS09610 (MKK04_09610) 2092031..2092954 - 924 WP_207833828.1 LysR family transcriptional regulator -
MKK04_RS09615 (MKK04_09615) 2093058..2093711 + 654 WP_063915060.1 oxygen-insensitive NAD(P)H nitroreductase -
MKK04_RS09620 (MKK04_09620) 2093811..2094260 + 450 WP_063915059.1 DUF2384 domain-containing protein Antitoxin
MKK04_RS09625 (MKK04_09625) 2094257..2094694 + 438 WP_063915058.1 RES family NAD+ phosphorylase Toxin
MKK04_RS09630 (MKK04_09630) 2094702..2095856 - 1155 WP_207833826.1 aminotransferase class V-fold PLP-dependent enzyme -
MKK04_RS09635 (MKK04_09635) 2096052..2096978 - 927 WP_063915056.1 LysR family transcriptional regulator -
MKK04_RS09640 (MKK04_09640) 2097119..2098348 + 1230 WP_063915055.1 acyl-CoA dehydrogenase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

RES domain

(3-137)

Antitoxin

Antitoxin Xre-like, helix-turn-helix domain

(33-91)


Sequences

Toxin        


Download         Length: 146 a.a.        Molecular weight: 15997.24 Da        Isoelectric Point: 5.1199

>T237216 WP_063915058.1 NZ_CP092827:2094257-2094694 [Pseudomonas sp. LS.1a]
VILWRISAYADLSGTGGLRISGRWHQAGRPVVYAATSPAGAMLEVLVHLEIDPEDFPSTMRLLRIELPDTVSQAQLPVLQ
PGWSSQTELTRGLGNRFLDECSALLLPVPSAIMPSTTNYLFNPRHPQANSARLEVEDFTPDSRLF

Download         Length: 438 bp

>T237216 NZ_LR796240:c2520226-2519933 [Treponema socranskii subsp. buccale]
ATGGAAAAATTGACTGAATTTGATATGGCAGAATATCTTGATACCGAAGAATTACAAAAAGGCTATCTTGACTATAATGC
CAAAGAGGGGACACCTGAAGATTTACTCCGTGCAATAAACGCAGTGGCAAGGGCAAGGGGAATGACAAAGACGGCAAAGG
AAGCGGGCATTACAAGAGATGGGCTTTACAAGGCACTTGCCCCCGAAGCGAACCCCGCTTTTTCAACGGTGTTTAACATT
CTCCACGCTATCGGTTATACACTCACGCCTACACCGATAGCAAAAACGATGTAA

Antitoxin


Download         Length: 150 a.a.        Molecular weight: 16990.56 Da        Isoelectric Point: 6.3405

>AT237216 WP_063915059.1 NZ_CP092827:2093811-2094260 [Pseudomonas sp. LS.1a]
MLAEVLRDNGYHEYRARLHALLEIPELASDFEIHTRITHGFAATWLVKLTELGVFTPVERDQIIPLRTLKSRIERDQPLT
VEESDRLFRSAHITAMAEAVFGEAGKAKRWLSKPKERFSGLTPMQMLTTQQGTTQVEEMLLQIAEGFGL

Download         Length: 450 bp

>AT237216 NZ_LR796240:c2520518-2520210 [Treponema socranskii subsp. buccale]
GTGTATAAGGTATTACAGACAGAAACATATAAGAAATGGTTTAAAAAACTCCGTGATGAAAGAGCGAAATTCGCCATAGG
TCAAAGAATTGCAAGAATGACAGTTGGCAATTTCGGGGATTCCAAGACGGTAGGCGGTGGAGTTTTTGAGCTGAGGATAG
ATGTAGGAAAAGGCTACAGAGTTTATTTTACGAACAATGGAAAGCAGATTGTAATACTTCTTGTAGGCGGTGATAAATCA
ACACAAGATGAGGATATAAAGACCGCCAAGAAAATGGCAGGGGGTATCGATTATGGAAAAATTGACTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References