Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2011656..2011801 Replicon chromosome
Accession NZ_CP092793
Organism Klebsiella pneumoniae strain XH1507

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2011692..2011794 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2011656..2011801 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ML258_RS09850 (ML258_09850) 2006786..2008846 + 2061 WP_004151449.1 oligopeptidase B -
ML258_RS09855 (ML258_09855) 2008850..2009509 - 660 WP_002911407.1 exodeoxyribonuclease X -
ML258_RS09860 (ML258_09860) 2009588..2009818 - 231 WP_002911406.1 DNA polymerase III subunit theta -
ML258_RS09865 (ML258_09865) 2009931..2010305 + 375 WP_004151448.1 CopC domain-containing protein YobA -
ML258_RS09870 (ML258_09870) 2010309..2011178 + 870 WP_062955019.1 copper homeostasis membrane protein CopD -
ML258_RS09875 (ML258_09875) 2011195..2011533 + 339 WP_002911404.1 YebY family protein -
- 2011656..2011801 - 146 - - Antitoxin
- 2011692..2011794 + 103 - - Toxin
ML258_RS09880 (ML258_09880) 2012169..2012312 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
ML258_RS09885 (ML258_09885) 2012417..2013385 - 969 WP_004151446.1 VirK/YbjX family protein -
ML258_RS09890 (ML258_09890) 2013542..2014195 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
ML258_RS09895 (ML258_09895) 2014192..2014383 - 192 WP_002911395.1 YebW family protein -
ML258_RS09900 (ML258_09900) 2014481..2014720 - 240 WP_002911393.1 YebV family protein -
ML258_RS09905 (ML258_09905) 2014836..2016269 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T237176 NZ_CP092793:2011692-2011794 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT237176 NZ_CP092793:c2011801-2011656 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References