Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2012384..2012529 Replicon chromosome
Accession NZ_CP092786
Organism Klebsiella pneumoniae strain XH1508

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2012420..2012522 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2012384..2012529 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ML259_RS09865 (ML259_09865) 2007514..2009574 + 2061 WP_004151449.1 oligopeptidase B -
ML259_RS09870 (ML259_09870) 2009578..2010237 - 660 WP_002911407.1 exodeoxyribonuclease X -
ML259_RS09875 (ML259_09875) 2010316..2010546 - 231 WP_002911406.1 DNA polymerase III subunit theta -
ML259_RS09880 (ML259_09880) 2010659..2011033 + 375 WP_004151448.1 CopC domain-containing protein YobA -
ML259_RS09885 (ML259_09885) 2011037..2011906 + 870 WP_062955019.1 copper homeostasis membrane protein CopD -
ML259_RS09890 (ML259_09890) 2011923..2012261 + 339 WP_002911404.1 YebY family protein -
- 2012384..2012529 - 146 - - Antitoxin
- 2012420..2012522 + 103 - - Toxin
ML259_RS09895 (ML259_09895) 2012897..2013040 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
ML259_RS09900 (ML259_09900) 2013145..2014113 - 969 WP_004151446.1 VirK/YbjX family protein -
ML259_RS09905 (ML259_09905) 2014270..2014923 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
ML259_RS09910 (ML259_09910) 2014920..2015111 - 192 WP_002911395.1 YebW family protein -
ML259_RS09915 (ML259_09915) 2015209..2015448 - 240 WP_002911393.1 YebV family protein -
ML259_RS09920 (ML259_09920) 2015564..2016997 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T237147 NZ_CP092786:2012420-2012522 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT237147 NZ_CP092786:c2012529-2012384 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References