Detailed information of TA system
Overview
TA module
| Type | IV | Classification (family/domain) | abiEi-abiEii/AbiEii-AbiEi |
| Location | 945081..946554 | Replicon | chromosome |
| Accession | NZ_CP092776 | ||
| Organism | Mycoplasmopsis bovis strain L15762 | ||
Toxin (Protein)
| Gene name | abiEi | Uniprot ID | - |
| Locus tag | L8F44_RS04170 | Protein ID | WP_152028827.1 |
| Coordinates | 945688..946554 (+) | Length | 289 a.a. |
Antitoxin (Protein)
| Gene name | abiEii | Uniprot ID | - |
| Locus tag | L8F44_RS04165 | Protein ID | WP_152028826.1 |
| Coordinates | 945081..945695 (+) | Length | 205 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| L8F44_RS04130 (L8F44_04105) | 940082..940360 | + | 279 | WP_226066048.1 | hypothetical protein | - |
| L8F44_RS04135 (L8F44_04110) | 940381..941082 | - | 702 | WP_226690170.1 | variable surface lipoprotein | - |
| L8F44_RS04140 (L8F44_04115) | 941237..942133 | - | 897 | WP_255802112.1 | variable surface lipoprotein | - |
| L8F44_RS04145 (L8F44_04120) | 942573..942725 | - | 153 | Protein_790 | variable surface lipoprotein | - |
| L8F44_RS04150 (L8F44_04125) | 942924..943484 | - | 561 | WP_255802113.1 | variable surface lipoprotein | - |
| L8F44_RS04155 (L8F44_04130) | 943909..944094 | - | 186 | Protein_792 | variable surface lipoprotein | - |
| L8F44_RS04160 (L8F44_04135) | 944269..944898 | - | 630 | WP_255802114.1 | variable surface lipoprotein | - |
| L8F44_RS04165 (L8F44_04140) | 945081..945695 | + | 615 | WP_152028826.1 | type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein | Antitoxin |
| L8F44_RS04170 (L8F44_04145) | 945688..946554 | + | 867 | WP_152028827.1 | nucleotidyl transferase AbiEii/AbiGii toxin family protein | Toxin |
| L8F44_RS04175 (L8F44_04150) | 946669..947475 | + | 807 | WP_255802115.1 | variable surface lipoprotein | - |
| L8F44_RS04180 (L8F44_04155) | 947773..948051 | + | 279 | WP_226066048.1 | hypothetical protein | - |
| L8F44_RS04185 (L8F44_04160) | 948072..948731 | - | 660 | WP_226088677.1 | variable surface lipoprotein | - |
| L8F44_RS04190 (L8F44_04165) | 949016..949765 | + | 750 | WP_013456123.1 | tyrosine-type recombinase/integrase | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 289 a.a. Molecular weight: 33522.63 Da Isoelectric Point: 6.5024
>T237126 WP_152028827.1 NZ_CP092776:945688-946554 [Mycoplasmopsis bovis]
MNKNKLISLCHKIADENNANFNVVLIQYFMESILRRISKSNERDNFVFKGGFLLSNIMGLDKRATMDIDLELIKTQKISA
SKILEKFKSILNADDIDGIRYHILKYTDIRKEHKYSGINISVLCQIENIKQVISIDIASGDVITPKEIVYEYKSIFSNQD
FSILAYNIETMLSEKLETIFSFGHLNTRFKDFYDVYVIYTFKKKDIDINRLKDACYNTFKNRNSEFNIQQLLELITNIAF
NPLMNERKKYISQIANQQEIDFKAITNSIIELLELIKAEELTNNDEI
MNKNKLISLCHKIADENNANFNVVLIQYFMESILRRISKSNERDNFVFKGGFLLSNIMGLDKRATMDIDLELIKTQKISA
SKILEKFKSILNADDIDGIRYHILKYTDIRKEHKYSGINISVLCQIENIKQVISIDIASGDVITPKEIVYEYKSIFSNQD
FSILAYNIETMLSEKLETIFSFGHLNTRFKDFYDVYVIYTFKKKDIDINRLKDACYNTFKNRNSEFNIQQLLELITNIAF
NPLMNERKKYISQIANQQEIDFKAITNSIIELLELIKAEELTNNDEI
Download Length: 867 bp
>T237126 NZ_LR778151:c4399204-4398947 [Escherichia coli]
ATGAATTTATCCCGTCAGGAACAACATACCTTACACGTTCTCGCTAAAGGTAGACGTATTGCGCACGTCCGCGATTCTTC
AGGCCGCGTCACTTCCGTTGAATGCTACAGCCGCGAAGGGCTGTTGCTGACCGACTGCACGCTCGCCGTCTTCAAAAAAC
TCAAAACCAAAAAACTTATCAAGTCCGTCAATGGCCAGCCCTATCGAATCAACACCACCGAGCTGAATAAAGTTCGCGCT
CAGCTCGATAATCGCTAA
ATGAATTTATCCCGTCAGGAACAACATACCTTACACGTTCTCGCTAAAGGTAGACGTATTGCGCACGTCCGCGATTCTTC
AGGCCGCGTCACTTCCGTTGAATGCTACAGCCGCGAAGGGCTGTTGCTGACCGACTGCACGCTCGCCGTCTTCAAAAAAC
TCAAAACCAAAAAACTTATCAAGTCCGTCAATGGCCAGCCCTATCGAATCAACACCACCGAGCTGAATAAAGTTCGCGCT
CAGCTCGATAATCGCTAA
Antitoxin
Download Length: 205 a.a. Molecular weight: 24085.79 Da Isoelectric Point: 9.7565
>AT237126 WP_152028826.1 NZ_CP092776:945081-945695 [Mycoplasmopsis bovis]
MEQKNLNSKYYNAIFKLLHKNNGVITYKQLKENNISSIYLTRMIAKGVLIRKAKGIYILSDGHYDEYYFLSKNYKSLIFS
HYSALYLNNIIDIFPHQIDVTVYSGYNAKGIKKHANVYYCDRNKHSIGLSESKTLFGNKVKVYDFERTICDFVKLRKKTD
SEIFSKLISAYIKYENRDKKLYEYAYELGIHKKISEIFELFYE
MEQKNLNSKYYNAIFKLLHKNNGVITYKQLKENNISSIYLTRMIAKGVLIRKAKGIYILSDGHYDEYYFLSKNYKSLIFS
HYSALYLNNIIDIFPHQIDVTVYSGYNAKGIKKHANVYYCDRNKHSIGLSESKTLFGNKVKVYDFERTICDFVKLRKKTD
SEIFSKLISAYIKYENRDKKLYEYAYELGIHKKISEIFELFYE
Download Length: 615 bp
>AT237126 NZ_LR778151:c4398935-4398390 [Escherichia coli]
ATGACAGTACACCACTTCACTTTTCATATCACAGATAAAAGTGATGCCAGTGATATCCGGGAAGTCGAAACCCGCGCATT
TGGCTTCAGCAAAGAAGCCGATTTAGTGGCCTCTTTACTTGAGGATGAAAGCGCGCGCCCCGCGTTATCGCTGCTAGCCC
GATATGAAGGCAAAGCCGTCGGGCATATTTTATTTACCCGGGCAACCTTCAAAGGAGAAATGGATTCACCGTTGATGCAC
ATCCTCGCTCCCCTGGCGGTCATACCGGAATACCAAGGGATGGGCGTGGGAGGACGGTTGATACGCACTGGCATCGAGCA
CCTGAGGTTGATGGGCTGCCAGACGGTTTTTGTTCTCGGCCACGCCACCTATTACCCCCGACATGGGTTCGAACCCTGTG
CCGGAGACAAAGGCTATCCGGCACCTTATCCCATCCCGGAGGAGCACAAAGCCTGCTGGATGATGCAATCACTCACCGCT
CAGCCCATGACCCTGACCGGCCACATCCGGTGCGCAGACCCTGATGAAACCGGAGCACTGACGTGA
ATGACAGTACACCACTTCACTTTTCATATCACAGATAAAAGTGATGCCAGTGATATCCGGGAAGTCGAAACCCGCGCATT
TGGCTTCAGCAAAGAAGCCGATTTAGTGGCCTCTTTACTTGAGGATGAAAGCGCGCGCCCCGCGTTATCGCTGCTAGCCC
GATATGAAGGCAAAGCCGTCGGGCATATTTTATTTACCCGGGCAACCTTCAAAGGAGAAATGGATTCACCGTTGATGCAC
ATCCTCGCTCCCCTGGCGGTCATACCGGAATACCAAGGGATGGGCGTGGGAGGACGGTTGATACGCACTGGCATCGAGCA
CCTGAGGTTGATGGGCTGCCAGACGGTTTTTGTTCTCGGCCACGCCACCTATTACCCCCGACATGGGTTCGAACCCTGTG
CCGGAGACAAAGGCTATCCGGCACCTTATCCCATCCCGGAGGAGCACAAAGCCTGCTGGATGATGCAATCACTCACCGCT
CAGCCCATGACCCTGACCGGCCACATCCGGTGCGCAGACCCTGATGAAACCGGAGCACTGACGTGA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
Structures
Toxin
| Source | ID | Structure |
|---|
Antitoxin
| Source | ID | Structure |
|---|