Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1953399..1953544 Replicon chromosome
Accession NZ_CP092765
Organism Klebsiella pneumoniae strain bat15

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1953435..1953537 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1953399..1953544 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MKZ43_RS09600 (MKZ43_09600) 1948529..1950589 + 2061 WP_004151449.1 oligopeptidase B -
MKZ43_RS09605 (MKZ43_09605) 1950593..1951252 - 660 WP_002911407.1 exodeoxyribonuclease X -
MKZ43_RS09610 (MKZ43_09610) 1951331..1951561 - 231 WP_002911406.1 DNA polymerase III subunit theta -
MKZ43_RS09615 (MKZ43_09615) 1951674..1952048 + 375 WP_004151448.1 CopC domain-containing protein YobA -
MKZ43_RS09620 (MKZ43_09620) 1952052..1952921 + 870 WP_004151447.1 copper homeostasis membrane protein CopD -
MKZ43_RS09625 (MKZ43_09625) 1952938..1953276 + 339 WP_002911404.1 YebY family protein -
- 1953399..1953544 - 146 - - Antitoxin
- 1953435..1953537 + 103 - - Toxin
MKZ43_RS09630 (MKZ43_09630) 1953912..1954055 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
MKZ43_RS09635 (MKZ43_09635) 1954160..1955128 - 969 WP_004151446.1 VirK/YbjX family protein -
MKZ43_RS09640 (MKZ43_09640) 1955285..1955938 + 654 WP_002911396.1 protein-serine/threonine phosphatase -
MKZ43_RS09645 (MKZ43_09645) 1955935..1956126 - 192 WP_002911395.1 YebW family protein -
MKZ43_RS09650 (MKZ43_09650) 1956224..1956463 - 240 WP_002911393.1 YebV family protein -
MKZ43_RS09655 (MKZ43_09655) 1956579..1958012 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T237110 NZ_CP092765:1953435-1953537 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT237110 NZ_CP092765:c1953544-1953399 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References