Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1953313..1953458 Replicon chromosome
Accession NZ_CP092753
Organism Klebsiella pneumoniae strain bat17

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1953349..1953451 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1953313..1953458 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MKZ44_RS09595 (MKZ44_09595) 1948443..1950503 + 2061 WP_004151449.1 oligopeptidase B -
MKZ44_RS09600 (MKZ44_09600) 1950507..1951166 - 660 WP_002911407.1 exodeoxyribonuclease X -
MKZ44_RS09605 (MKZ44_09605) 1951245..1951475 - 231 WP_002911406.1 DNA polymerase III subunit theta -
MKZ44_RS09610 (MKZ44_09610) 1951588..1951962 + 375 WP_004151448.1 CopC domain-containing protein YobA -
MKZ44_RS09615 (MKZ44_09615) 1951966..1952835 + 870 WP_004151447.1 copper homeostasis membrane protein CopD -
MKZ44_RS09620 (MKZ44_09620) 1952852..1953190 + 339 WP_002911404.1 YebY family protein -
- 1953313..1953458 - 146 - - Antitoxin
- 1953349..1953451 + 103 - - Toxin
MKZ44_RS09625 (MKZ44_09625) 1953826..1953969 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
MKZ44_RS09630 (MKZ44_09630) 1954074..1955042 - 969 WP_004151446.1 VirK/YbjX family protein -
MKZ44_RS09635 (MKZ44_09635) 1955199..1955852 + 654 WP_002911396.1 protein-serine/threonine phosphatase -
MKZ44_RS09640 (MKZ44_09640) 1955849..1956040 - 192 WP_002911395.1 YebW family protein -
MKZ44_RS09645 (MKZ44_09645) 1956138..1956377 - 240 WP_002911393.1 YebV family protein -
MKZ44_RS09650 (MKZ44_09650) 1956493..1957926 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T237071 NZ_CP092753:1953349-1953451 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT237071 NZ_CP092753:c1953458-1953313 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References