Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 2019673..2019818 | Replicon | chromosome |
| Accession | NZ_CP092717 | ||
| Organism | Klebsiella pneumoniae strain HvKp-su1 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 2019709..2019811 (+) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 2019673..2019818 (-) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| MKX18_RS09910 (MKX18_09910) | 2014803..2016863 | + | 2061 | WP_004151449.1 | oligopeptidase B | - |
| MKX18_RS09915 (MKX18_09915) | 2016867..2017526 | - | 660 | WP_002911407.1 | exodeoxyribonuclease X | - |
| MKX18_RS09920 (MKX18_09920) | 2017605..2017835 | - | 231 | WP_002911406.1 | DNA polymerase III subunit theta | - |
| MKX18_RS09925 (MKX18_09925) | 2017948..2018322 | + | 375 | WP_004151448.1 | CopC domain-containing protein YobA | - |
| MKX18_RS09930 (MKX18_09930) | 2018326..2019195 | + | 870 | WP_062955019.1 | copper homeostasis membrane protein CopD | - |
| MKX18_RS09935 (MKX18_09935) | 2019212..2019550 | + | 339 | WP_002911404.1 | YebY family protein | - |
| - | 2019673..2019818 | - | 146 | - | - | Antitoxin |
| - | 2019709..2019811 | + | 103 | - | - | Toxin |
| MKX18_RS09940 (MKX18_09940) | 2020186..2020329 | - | 144 | WP_002911398.1 | Ecr family regulatory small membrane protein | - |
| MKX18_RS09945 (MKX18_09945) | 2020434..2021402 | - | 969 | WP_004151446.1 | VirK/YbjX family protein | - |
| MKX18_RS09950 (MKX18_09950) | 2021559..2022212 | + | 654 | WP_004180432.1 | protein-serine/threonine phosphatase | - |
| MKX18_RS09955 (MKX18_09955) | 2022209..2022400 | - | 192 | WP_002911395.1 | YebW family protein | - |
| MKX18_RS09960 (MKX18_09960) | 2022498..2022737 | - | 240 | WP_002911393.1 | YebV family protein | - |
| MKX18_RS09965 (MKX18_09965) | 2022853..2024286 | - | 1434 | WP_004148845.1 | 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 103 bp
>T237026 NZ_CP092717:2019709-2019811 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
Antitoxin
Download Length: 146 bp
>AT237026 NZ_CP092717:c2019818-2019673 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
