Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 3119749..3119894 Replicon chromosome
Accession NZ_CP092648
Organism Klebsiella pneumoniae strain KP7728

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 3119756..3119858 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 3119749..3119894 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MJ615_RS15295 3115281..3116714 + 1434 WP_064190786.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
MJ615_RS15300 3116830..3117069 + 240 WP_002911393.1 YebV family protein -
MJ615_RS15305 3117167..3117358 + 192 WP_002911395.1 YebW family protein -
MJ615_RS15310 3117355..3118008 - 654 WP_004180432.1 protein-serine/threonine phosphatase -
MJ615_RS15315 3118165..3119133 + 969 WP_074195444.1 VirK/YbjX family protein -
MJ615_RS15320 3119238..3119381 + 144 WP_002911398.1 Ecr family regulatory small membrane protein -
- 3119749..3119894 + 146 - - Antitoxin
- 3119756..3119858 - 103 - - Toxin
MJ615_RS15325 3120017..3120355 - 339 WP_002911404.1 YebY family protein -
MJ615_RS15330 3120372..3121241 - 870 WP_004175431.1 copper homeostasis membrane protein CopD -
MJ615_RS15335 3121245..3121619 - 375 WP_004151448.1 CopC domain-containing protein YobA -
MJ615_RS15340 3121732..3121962 + 231 WP_002911406.1 DNA polymerase III subunit theta -
MJ615_RS15345 3122041..3122700 + 660 WP_002911407.1 exodeoxyribonuclease X -
MJ615_RS15350 3122704..3124764 - 2061 WP_004151449.1 oligopeptidase B -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T236878 NZ_CP092648:c3119858-3119756 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT236878 NZ_CP092648:3119749-3119894 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References