236763

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) ygfYX/Cpta(toxin)
Location 3379587..3380256 Replicon chromosome
Accession NZ_CP092630
Organism Shewanella xiamenensis strain CQ-Y1

Toxin (Protein)


Gene name ygfX Uniprot ID -
Locus tag MKD32_RS14880 Protein ID WP_240292332.1
Coordinates 3379587..3380027 (-) Length 147 a.a.

Antitoxin (Protein)


Gene name ygfY Uniprot ID -
Locus tag MKD32_RS14885 Protein ID WP_139122633.1
Coordinates 3380008..3380256 (-) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MKD32_RS14855 (MKD32_14855) 3375001..3375474 - 474 WP_055646698.1 SoxR reducing system RseC family protein -
MKD32_RS14860 (MKD32_14860) 3375486..3376418 - 933 WP_240292331.1 MucB/RseB C-terminal domain-containing protein -
MKD32_RS14865 (MKD32_14865) 3376431..3377042 - 612 WP_037427581.1 RseA family anti-sigma factor -
MKD32_RS14870 (MKD32_14870) 3377084..3377662 - 579 WP_037415584.1 RNA polymerase sigma factor RpoE -
MKD32_RS14875 (MKD32_14875) 3377852..3379465 + 1614 WP_037415581.1 L-aspartate oxidase -
MKD32_RS14880 (MKD32_14880) 3379587..3380027 - 441 WP_240292332.1 hypothetical protein Toxin
MKD32_RS14885 (MKD32_14885) 3380008..3380256 - 249 WP_139122633.1 succinate dehydrogenase assembly factor 2 Antitoxin
MKD32_RS14890 (MKD32_14890) 3380341..3381249 - 909 WP_069455412.1 transcriptional activator NhaR -
MKD32_RS14895 (MKD32_14895) 3381344..3381730 - 387 WP_037415577.1 hypothetical protein -
MKD32_RS14900 (MKD32_14900) 3381733..3382902 - 1170 WP_037415576.1 Na+/H+ antiporter NhaA -
MKD32_RS14905 (MKD32_14905) 3383020..3383814 - 795 WP_037415574.1 thymidylate synthase -
MKD32_RS14910 (MKD32_14910) 3383814..3384620 - 807 WP_037415571.1 prolipoprotein diacylglyceryl transferase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(5-134)

Antitoxin

Flavinator of succinate dehydrogenase

(7-77)


Sequences

Toxin        


Download         Length: 147 a.a.        Molecular weight: 16860.72 Da        Isoelectric Point: 7.6899

>T236763 WP_240292332.1 NZ_CP092630:c3380027-3379587 [Shewanella xiamenensis]
VAELRHSFSVKASFDQRLSLVVFVCVCSTSLLLWPETDTAVLHGLRAIFAVLILGFLCSQLWQLRKWHCRFELNGQGDGW
LSTGEAFHVLPRTWVTPFICLVYYQSADRLHLLPLWADMFSDTDYRHLCRLLLKVKTQAVSQHELL

Download         Length: 441 bp

>T236763 NZ_LR738720:c741231-740386 [Streptococcus suis]
ATGAACAAAGCTAAATTAACAGCACTCTGTCATAAAATATCAAAGAATACTGGTTTAACCTTTAATTCCGTGATGACCTA
TTACTTCCTAGAAGTCATTTTGAAAAAATTAAGTCAAAGTTCTTATTCAAATCACTACATCTTCAAAGGAGGATTCCTAC
TGTCGAATGTCATCGGAGTTGAATCTCGTAGCACTGTTGATATTGACTTTTTATTCCATCAAATAACACTCTCAGAAGAA
ACTGTTAAGCAGCAACTCAAGGAAATTTTAGCAGATTCCGAAGAAGGTATCTCTTTTGTGATTCAATCAATCACAGCTAT
TAAAGAAAGTGATGACTATGGTGGCTATCGAGCAACCATTTTGTGCCAACTTGAGAATATTAAACAAGTTATTCATTTGG
ATATTGCGACAGGTGATGTTGTAACTCCTCAGCCGATTACATACGACTATAAAGCTATTTTTGATGAAGACAATTTTCCA
ATCATTGCTTATACAATTGAAACAATTCTAGCTGAGAAACTTCAAACCATCTATTCACGCAACTTCTTGAACAGTAGAAG
CAAAGATTTTTACGATGTTTATATTCTTTCAAAACTGAAGAAAGAAGACATTGACTTCATTCAATTGAAAAATGCCTGTC
AGAGAACATTTTCATATCGCGAAACAGAACTCGATTTTGAAAAGATTATTGAACTACTCGAAAGGTTCAAATCTGACCCT
ATTCAGAATAAACAATGGCAAAATTATTCAAAAAAATATAGCTATACAAAGGGGATTTCACTTGCAGATGTTCTTGATGA
GATGATTCGTTTTATAACAGTTCTCATTTCTATAAATTCTGATTAA

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9627.21 Da        Isoelectric Point: 4.3440

>AT236763 WP_139122633.1 NZ_CP092630:c3380256-3380008 [Shewanella xiamenensis]
MELMNIARVRWACRRGMLELDVLFQPFVENVYQDLSDEDKALFIRLLECEDPELFAWFMGHEVCPDPELARMVVQVRGRA
AP

Download         Length: 249 bp

>AT236763 NZ_LR738720:c741818-741228 [Streptococcus suis]
ATGTCAAAAAAAGAGATTCTACTCGATTTTATAGAAAAGAACAATGGAATTGTCACAAACAAAGATTGTAAAGCACTAGG
TATTCCAACAATATATCTGACAAGACTAGAGAAAGAAGGCATTATCTTCCGAGTTGAAAAAGGTATTTTCCTAACCCAAA
ACGGAGACTATGATGAATACTACTTCTTTCAATATCGTTTTCCTAAGGCTATTTTCTCTTATATTTCGGCACTGTATCTA
CAACAGTTTACAGATGAAATTCCACAATATTTTGATGTGACAGTTCCTAGAGGCTACCGCTTTAATACTCCTCCAGCCAA
TCTAAATATTCACTTTGTCTCTAAAGAATACAGCGAGCTGGGAATGACTACTGTACCTACTCCTATGGGAAACAACGTAA
GGGTATATGATTTTGAACGTATTATTTGTGATTTTGTAATACATCGAGAAAAGATTGATTCCGAACTCTTTGTCAAGACA
CTTCAATCTTATGGGAACTATCCTAAAAAAAATCTAGCAAAACTCTATGAATATGCGACAAAAATGAATACTTTAGAAAA
AGTTAAACAAACTCTGGAGGTTCTAATATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References