236761

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/ParE-YefM
Location 384573..385123 Replicon chromosome
Accession NZ_CP092630
Organism Shewanella xiamenensis strain CQ-Y1

Toxin (Protein)


Gene name parE Uniprot ID A0A073KJU4
Locus tag MKD32_RS01835 Protein ID WP_037423263.1
Coordinates 384573..384872 (-) Length 100 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID V1DMX4
Locus tag MKD32_RS01840 Protein ID WP_023266112.1
Coordinates 384881..385123 (-) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MKD32_RS01815 (MKD32_01815) 379945..381132 + 1188 WP_240293458.1 benzoate/H(+) symporter BenE family transporter -
MKD32_RS01820 (MKD32_01820) 381190..381645 - 456 WP_144345218.1 GNAT family N-acetyltransferase -
MKD32_RS01825 (MKD32_01825) 382446..383387 - 942 WP_240292850.1 hypothetical protein -
MKD32_RS01830 (MKD32_01830) 383506..384015 - 510 WP_240292851.1 hypothetical protein -
MKD32_RS01835 (MKD32_01835) 384573..384872 - 300 WP_037423263.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
MKD32_RS01840 (MKD32_01840) 384881..385123 - 243 WP_023266112.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
MKD32_RS01845 (MKD32_01845) 385318..386061 - 744 WP_037423265.1 hypothetical protein -
MKD32_RS01850 (MKD32_01850) 386072..387325 - 1254 WP_037423269.1 beta-ketoacyl-ACP synthase -
MKD32_RS01855 (MKD32_01855) 387326..388051 - 726 WP_037423272.1 3-ketoacyl-ACP reductase FabG2 -
MKD32_RS01860 (MKD32_01860) 388177..388716 - 540 WP_084294839.1 hotdog family protein -
MKD32_RS01865 (MKD32_01865) 388722..389945 - 1224 WP_240292852.1 beta-ketoacyl-[acyl-carrier-protein] synthase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-90)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-55)


Sequences

Toxin        


Download         Length: 100 a.a.        Molecular weight: 11457.26 Da        Isoelectric Point: 9.6274

>T236761 WP_037423263.1 NZ_CP092630:c384872-384573 [Shewanella xiamenensis]
MNNKRYKLSMLAQAHLLKIKDYTLQHVSESQWHKYKESLISGLQMLANHPGLGRSCNDIYPNGFYFPIGKHTAYFTKEDD
FILIVALLGQPQLPQNHLK

Download         Length: 300 bp

>T236761 NZ_LR738720:570310-570492 [Streptococcus suis]
ATGCCTATGACACAAAAAGAAATGGTTAAACTTCTTACCGCCAACGGTTGGACAAAGACCAAAGGCGGTAAAGGGTCACA
CGTTAAACTTGAAAAAGCAGGCGAGCGACCTATAACCATTCCCCACGGTGAAATTAACAAATACACCGAAAGGGGTATCA
AAAAGCAAGCAGGGCTGTTATAA

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 8954.13 Da        Isoelectric Point: 4.7483

>AT236761 WP_023266112.1 NZ_CP092630:c385123-384881 [Shewanella xiamenensis]
MQTLTANDAKRNFGELLLNAQREPIKISKNSKDAVVVMSIHDYEQLEAMKADYLKHCFNAAKEDLAQGNVVDGEDFLNAL

Download         Length: 243 bp

>AT236761 NZ_LR738720:570532-570984 [Streptococcus suis]
ATGCTTGTCACTTATCCAGCTTTATTTTATTATGACGATACAGACGGAGCTAGCGCCCCTTATTTTGTCACTTTCCCAGA
CTTTGAACATTCAGCAACTCAAGGCGAAGATATGGCAAACGCTATGGCAATGGCTAGTGATTGGTTAGGTATTCATCTAG
CTGATTATATTGAGAATGGGCGAGATATTCCCATTCCTACCCCTATTAACACCTTATCTTTAGCAGATAATAACCCTTTC
CATGATGATGAGGATATAGAGCTTATCTATGACCCTAGTAAGTCTTTTATTTCTATGGTTATGGTTGATGTTGCCGAGTA
TTTAGGTAGCCAAGAACCTATAAAGAAGACTCTAACTATCCCACGTTGGGCGGATACTTTAGGGCGTGAGCTAGGATTGA
ATTTCTCACAGACCTTAACAGACGCTATTGCAGATAAGAAAATTCATGCTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A073KJU4

Antitoxin

Source ID Structure
AlphaFold DB V1DMX4

References