Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1930525..1930670 Replicon chromosome
Accession NZ_CP092589
Organism Klebsiella pneumoniae strain EFN 299

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1930561..1930663 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1930525..1930670 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MKT41_RS09450 (MKT41_09450) 1925655..1927715 + 2061 WP_004151449.1 oligopeptidase B -
MKT41_RS09455 (MKT41_09455) 1927719..1928378 - 660 WP_002911407.1 exodeoxyribonuclease X -
MKT41_RS09460 (MKT41_09460) 1928457..1928687 - 231 WP_002911406.1 DNA polymerase III subunit theta -
MKT41_RS09465 (MKT41_09465) 1928800..1929174 + 375 WP_004151448.1 CopC domain-containing protein YobA -
MKT41_RS09470 (MKT41_09470) 1929178..1930047 + 870 WP_004189267.1 copper homeostasis membrane protein CopD -
MKT41_RS09475 (MKT41_09475) 1930064..1930402 + 339 WP_004189269.1 YebY family protein -
- 1930525..1930670 - 146 - - Antitoxin
- 1930561..1930663 + 103 - - Toxin
MKT41_RS09480 (MKT41_09480) 1931037..1931180 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
MKT41_RS09485 (MKT41_09485) 1931285..1932253 - 969 WP_004151446.1 VirK/YbjX family protein -
MKT41_RS09490 (MKT41_09490) 1932410..1933063 + 654 WP_004189273.1 protein-serine/threonine phosphatase -
MKT41_RS09495 (MKT41_09495) 1933060..1933251 - 192 WP_002911395.1 YebW family protein -
MKT41_RS09500 (MKT41_09500) 1933349..1933588 - 240 WP_002911393.1 YebV family protein -
MKT41_RS09505 (MKT41_09505) 1933704..1935137 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T236714 NZ_CP092589:1930561-1930663 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT236714 NZ_CP092589:c1930670-1930525 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References