Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2113195..2113340 Replicon chromosome
Accession NZ_CP092536
Organism Klebsiella pneumoniae strain 2021CK-00720

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2113231..2113333 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2113195..2113340 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
UPHL_RS10055 2108325..2110385 + 2061 WP_004151449.1 oligopeptidase B -
UPHL_RS10060 2110389..2111048 - 660 WP_002911407.1 exodeoxyribonuclease X -
UPHL_RS10065 2111127..2111357 - 231 WP_002911406.1 DNA polymerase III subunit theta -
UPHL_RS10070 2111470..2111844 + 375 WP_004151448.1 CopC domain-containing protein YobA -
UPHL_RS10075 2111848..2112717 + 870 WP_004175431.1 copper homeostasis membrane protein CopD -
UPHL_RS10080 2112734..2113072 + 339 WP_002911404.1 YebY family protein -
- 2113195..2113340 - 146 - - Antitoxin
- 2113231..2113333 + 103 - - Toxin
UPHL_RS10085 2113708..2113851 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
UPHL_RS10090 2113956..2114924 - 969 WP_004151446.1 VirK/YbjX family protein -
UPHL_RS10095 2115081..2115734 + 654 WP_004891053.1 protein-serine/threonine phosphatase -
UPHL_RS10100 2115731..2115922 - 192 WP_002911395.1 YebW family protein -
UPHL_RS10105 2116020..2116259 - 240 WP_002911393.1 YebV family protein -
UPHL_RS10110 2116375..2117808 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T236456 NZ_CP092536:2113231-2113333 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT236456 NZ_CP092536:c2113340-2113195 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References