Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2130789..2131057 Replicon chromosome
Accession NZ_CP092534
Organism Escherichia coli strain DS566

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2130917..2131019 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2130789..2131057 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MKD44_RS10140 2127342..2128004 - 663 WP_000944258.1 exodeoxyribonuclease X -
MKD44_RS10145 2128028..2128684 - 657 WP_000011664.1 carbon-nitrogen hydrolase family protein YobB -
MKD44_RS10150 2128786..2129016 - 231 WP_000916763.1 DNA polymerase III subunit theta -
MKD44_RS10155 2129155..2129529 + 375 WP_000168747.1 CopC domain-containing protein YobA -
MKD44_RS10160 2129533..2130405 + 873 WP_000879311.1 copper homeostasis membrane protein CopD -
MKD44_RS10165 2130418..2130759 + 342 WP_000984819.1 YebY family protein -
- 2130789..2131057 - 269 - - Antitoxin
- 2130917..2131019 + 103 - - Toxin
MKD44_RS10170 2131154..2131810 + 657 WP_000812744.1 protein-serine/threonine phosphatase -
MKD44_RS10175 2131811..2132002 - 192 WP_024186842.1 YebW family protein -
MKD44_RS10180 2132107..2132343 - 237 WP_001295499.1 YebV family protein -
MKD44_RS10185 2132462..2133901 - 1440 WP_024186841.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T236430 NZ_CP092534:2130917-2131019 [Escherichia coli]
GCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 269 bp

>AT236430 NZ_CP092534:c2131057-2130789 [Escherichia coli]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCTCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References