Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2130768..2131036 Replicon chromosome
Accession NZ_CP092533
Organism Escherichia coli strain DS566-1

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2130896..2130998 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2130768..2131036 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MKD47_RS10140 2127321..2127983 - 663 WP_000944258.1 exodeoxyribonuclease X -
MKD47_RS10145 2128007..2128663 - 657 WP_000011664.1 carbon-nitrogen hydrolase family protein YobB -
MKD47_RS10150 2128765..2128995 - 231 WP_000916763.1 DNA polymerase III subunit theta -
MKD47_RS10155 2129134..2129508 + 375 WP_000168747.1 CopC domain-containing protein YobA -
MKD47_RS10160 2129512..2130384 + 873 WP_000879311.1 copper homeostasis membrane protein CopD -
MKD47_RS10165 2130397..2130738 + 342 WP_000984819.1 YebY family protein -
- 2130768..2131036 - 269 - - Antitoxin
- 2130896..2130998 + 103 - - Toxin
MKD47_RS10170 2131133..2131789 + 657 WP_000812744.1 protein-serine/threonine phosphatase -
MKD47_RS10175 2131790..2131981 - 192 WP_024186842.1 YebW family protein -
MKD47_RS10180 2132086..2132322 - 237 WP_001295499.1 YebV family protein -
MKD47_RS10185 2132441..2133880 - 1440 WP_024186841.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T236402 NZ_CP092533:2130896-2130998 [Escherichia coli]
GCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 269 bp

>AT236402 NZ_CP092533:c2131036-2130768 [Escherichia coli]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCTCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References