Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | vagCD/VapC-VagC |
Location | 4033664..4034301 | Replicon | chromosome |
Accession | NZ_CP092460 | ||
Organism | Dickeya fangzhongdai strain AP6 |
Toxin (Protein)
Gene name | vagD | Uniprot ID | - |
Locus tag | FXN80_RS17870 | Protein ID | WP_161129963.1 |
Coordinates | 4033664..4034074 (-) | Length | 137 a.a. |
Antitoxin (Protein)
Gene name | vagC | Uniprot ID | - |
Locus tag | FXN80_RS17875 | Protein ID | WP_161129964.1 |
Coordinates | 4034071..4034301 (-) | Length | 77 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
FXN80_RS17840 (FXN80_17840) | 4028835..4029737 | + | 903 | WP_161129957.1 | LysR substrate-binding domain-containing protein | - |
FXN80_RS17845 (FXN80_17845) | 4029867..4030205 | - | 339 | WP_161129958.1 | carboxymuconolactone decarboxylase family protein | - |
FXN80_RS17850 (FXN80_17850) | 4030222..4030791 | - | 570 | WP_161129959.1 | TetR/AcrR family transcriptional regulator | - |
FXN80_RS17855 (FXN80_17855) | 4030981..4031538 | - | 558 | WP_161129960.1 | OsmC family protein | - |
FXN80_RS17860 (FXN80_17860) | 4031924..4032391 | + | 468 | WP_161129961.1 | GNAT family N-acetyltransferase | - |
FXN80_RS17865 (FXN80_17865) | 4032525..4033505 | - | 981 | WP_161129962.1 | restriction endonuclease | - |
FXN80_RS17870 (FXN80_17870) | 4033664..4034074 | - | 411 | WP_161129963.1 | PIN domain-containing protein | Toxin |
FXN80_RS17875 (FXN80_17875) | 4034071..4034301 | - | 231 | WP_161129964.1 | type II toxin-antitoxin system VapB family antitoxin | Antitoxin |
FXN80_RS17880 (FXN80_17880) | 4035371..4036534 | - | 1164 | WP_161129965.1 | tyrosine-type recombinase/integrase | - |
FXN80_RS17890 (FXN80_17890) | 4036929..4038182 | - | 1254 | WP_121480525.1 | glutamate-5-semialdehyde dehydrogenase | - |
FXN80_RS17895 (FXN80_17895) | 4038193..4039296 | - | 1104 | WP_038919997.1 | glutamate 5-kinase | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 137 a.a. Molecular weight: 14408.36 Da Isoelectric Point: 4.5355
>T236202 WP_161129963.1 NZ_CP092460:c4034074-4033664 [Dickeya fangzhongdai]
VNRTYMLDTRFCAFILREQPEAVLGRLEQAVLRGHRIVISAVTWAELSQAAREDSPATQALADAFCASLDAVLPWDRAAV
DATTEIKAALAATGTPLGPNDAAIAGHAIAAGAVLVTRNGEEFERVPGLILQDWAG
VNRTYMLDTRFCAFILREQPEAVLGRLEQAVLRGHRIVISAVTWAELSQAAREDSPATQALADAFCASLDAVLPWDRAAV
DATTEIKAALAATGTPLGPNDAAIAGHAIAAGAVLVTRNGEEFERVPGLILQDWAG
Download Length: 411 bp
>T236202 NZ_LR213452:c2686129-2685755 [Shigella flexneri]
ATGAAAACATTATCCGACACACATGTACGGGAGGTATCTCGCTGCCCGTCTCCCGTCACCATCTGGCAGACACTGCTCAT
CCGACTGCTGGACCAGCATTATGGCCTCACACTGAATGACACACCGTTTGTCGATGAACGTGTGATTGAGCAGCATATTG
AGGCAGGCATTTCACTGTGTGATGCAGTTAATTTTCTCGTGGAAAAATACGCGCTGGTGCGTACCGACCAGCCGGGATTC
AGCACCTGTCCCCGCTCTCAGTTAATAAACAGTATTGATATCCTCCGGGCTCGCCGGGCGACCGGCCTGATGACCCGCGA
CAATTACAGAACGGTAAATAACATTACCCTGGGTAAGTATCCGGAGGCGAAATGA
ATGAAAACATTATCCGACACACATGTACGGGAGGTATCTCGCTGCCCGTCTCCCGTCACCATCTGGCAGACACTGCTCAT
CCGACTGCTGGACCAGCATTATGGCCTCACACTGAATGACACACCGTTTGTCGATGAACGTGTGATTGAGCAGCATATTG
AGGCAGGCATTTCACTGTGTGATGCAGTTAATTTTCTCGTGGAAAAATACGCGCTGGTGCGTACCGACCAGCCGGGATTC
AGCACCTGTCCCCGCTCTCAGTTAATAAACAGTATTGATATCCTCCGGGCTCGCCGGGCGACCGGCCTGATGACCCGCGA
CAATTACAGAACGGTAAATAACATTACCCTGGGTAAGTATCCGGAGGCGAAATGA
Antitoxin
Download Length: 77 a.a. Molecular weight: 8634.83 Da Isoelectric Point: 4.7863
>AT236202 WP_161129964.1 NZ_CP092460:c4034301-4034071 [Dickeya fangzhongdai]
MRTVSIFKNGNNRAIRLPRDLDFEGVSELEIVREGDCIILRPVRPAWSSFALMDRAGPEFMAEREVVISDNGRGEQ
MRTVSIFKNGNNRAIRLPRDLDFEGVSELEIVREGDCIILRPVRPAWSSFALMDRAGPEFMAEREVVISDNGRGEQ
Download Length: 231 bp
>AT236202 NZ_LR213452:c2686550-2686176 [Shigella flexneri]
GTGTCAGACAAACTCTCCGGGATAACTCATCCCGATGACAATCACGACCGCCCCTGGTGGGGGCTTCCCTGCACAGTGAG
GCCCTGTTTTGGCGCTCGTCTGGTGCAAGAGGGTAACCGCCTGTATTACCTTGCCGACCGCGCCGGTATCAGAGGCCGCT
TCAGCGACGCAGATGCATACCATCTGGACCAGGCCTTTCCGCTGCTGATGAAACAACTGGAACTCATGCTCACCAGCGGT
GAACTGAATCCCCGATATCAGCATACCGTCACGCTGTATGCAAAAGGGCTGACCTGCGAAGCCGACACCCTCGGCTCCTG
TGGTTACGTTTATCTGGCTGTTTATCCGACACCAGCACCCGCAACCACCTCATAA
GTGTCAGACAAACTCTCCGGGATAACTCATCCCGATGACAATCACGACCGCCCCTGGTGGGGGCTTCCCTGCACAGTGAG
GCCCTGTTTTGGCGCTCGTCTGGTGCAAGAGGGTAACCGCCTGTATTACCTTGCCGACCGCGCCGGTATCAGAGGCCGCT
TCAGCGACGCAGATGCATACCATCTGGACCAGGCCTTTCCGCTGCTGATGAAACAACTGGAACTCATGCTCACCAGCGGT
GAACTGAATCCCCGATATCAGCATACCGTCACGCTGTATGCAAAAGGGCTGACCTGCGAAGCCGACACCCTCGGCTCCTG
TGGTTACGTTTATCTGGCTGTTTATCCGACACCAGCACCCGCAACCACCTCATAA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Structures
Toxin
Source | ID | Structure |
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Antitoxin
Source | ID | Structure |
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