Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | vapBC/LOTUS_5_Limkain_b1-Phd |
Location | 196881..197566 | Replicon | plasmid pRSpK102b |
Accession | NZ_CP092438 | ||
Organism | Rhizobium sp. K102 |
Toxin (Protein)
Gene name | vapC | Uniprot ID | - |
Locus tag | MHI61_RS31555 | Protein ID | WP_239793726.1 |
Coordinates | 196881..197303 (-) | Length | 141 a.a. |
Antitoxin (Protein)
Gene name | vapB | Uniprot ID | - |
Locus tag | MHI61_RS31560 | Protein ID | WP_239793727.1 |
Coordinates | 197300..197566 (-) | Length | 89 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
MHI61_RS31535 (MHI61_31540) | 192840..194192 | + | 1353 | WP_239793723.1 | LLM class flavin-dependent oxidoreductase | - |
MHI61_RS31540 (MHI61_31545) | 194203..195054 | + | 852 | WP_239793724.1 | ABC transporter permease | - |
MHI61_RS31545 (MHI61_31550) | 195090..196073 | + | 984 | WP_239793725.1 | ABC transporter substrate-binding protein | - |
MHI61_RS31550 (MHI61_31555) | 196083..196852 | + | 770 | Protein_191 | ABC transporter ATP-binding protein | - |
MHI61_RS31555 (MHI61_31560) | 196881..197303 | - | 423 | WP_239793726.1 | type II toxin-antitoxin system VapC family toxin | Toxin |
MHI61_RS31560 (MHI61_31565) | 197300..197566 | - | 267 | WP_239793727.1 | type II toxin-antitoxin system Phd/YefM family antitoxin | Antitoxin |
MHI61_RS31565 (MHI61_31570) | 197637..199451 | - | 1815 | WP_239793728.1 | chloride channel protein | - |
MHI61_RS31570 (MHI61_31575) | 199657..200094 | + | 438 | WP_239793729.1 | helix-turn-helix domain-containing protein | - |
MHI61_RS31575 (MHI61_31580) | 200119..200907 | - | 789 | WP_239793730.1 | ABC transporter ATP-binding protein | - |
MHI61_RS31580 (MHI61_31585) | 200904..201956 | - | 1053 | WP_239793731.1 | iron ABC transporter permease | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
- | inside | Non-Mobilizable plasmid | - | - | 1..405132 | 405132 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 141 a.a. Molecular weight: 15823.14 Da Isoelectric Point: 5.0179
>T236094 WP_239793726.1 NZ_CP092438:c197303-196881 [Rhizobium sp. K102]
VRLLLDTNVLSEVTRPNPDMRVLAWLDQLDEDRSFISIVSIAEIRRGVALMDERRKRDALAEWLARELPQRFERRIIPVD
EPVASAWGDLMGRAKRSGRGLSSMDGLIAATAAAHDLTLATRNTRDFEGFGIELIDPWIV
VRLLLDTNVLSEVTRPNPDMRVLAWLDQLDEDRSFISIVSIAEIRRGVALMDERRKRDALAEWLARELPQRFERRIIPVD
EPVASAWGDLMGRAKRSGRGLSSMDGLIAATAAAHDLTLATRNTRDFEGFGIELIDPWIV
Download Length: 423 bp
>T236094 NZ_LR135309:26633-26983 [Enterococcus faecium]
ATGGTGAGAAAACCTAGACAAGGCGATATTCTATTATTGAATACAGCACCTCGATCTGGACACGAACAGACAGGTAAAAG
ACCTTATATTGTTTTAAGTCATGATATTATTGCGGATTATAGTAACGTTGTTACAGTTGCTCCAATTTCTAGTACAACTA
GAAACTATCCGCTATATGTAAATATAAACTCAGAATATGAAATGAAGACAACAGGAAAAGTATTATTAGATCAACTAACG
ACAATTGATTATGAAGCCAGAGAGTGTATTTTTTTGGAAAAAGCGCATGATAGTTTAGTTGAGGAGTTATTGATGAAAGT
TAGAACAGTTTTTCAAAAAGTAAGCAAATAA
ATGGTGAGAAAACCTAGACAAGGCGATATTCTATTATTGAATACAGCACCTCGATCTGGACACGAACAGACAGGTAAAAG
ACCTTATATTGTTTTAAGTCATGATATTATTGCGGATTATAGTAACGTTGTTACAGTTGCTCCAATTTCTAGTACAACTA
GAAACTATCCGCTATATGTAAATATAAACTCAGAATATGAAATGAAGACAACAGGAAAAGTATTATTAGATCAACTAACG
ACAATTGATTATGAAGCCAGAGAGTGTATTTTTTTGGAAAAAGCGCATGATAGTTTAGTTGAGGAGTTATTGATGAAAGT
TAGAACAGTTTTTCAAAAAGTAAGCAAATAA
Antitoxin
Download Length: 89 a.a. Molecular weight: 9720.87 Da Isoelectric Point: 5.1617
>AT236094 WP_239793727.1 NZ_CP092438:c197566-197300 [Rhizobium sp. K102]
MQPSRQGDESWTVASAKAKLSEVIERAQSAPQTITRNGKPSVVVVSAEEWQRKTARKGTLAEFLMSSPLRGADLDLERQG
DEPRDPEL
MQPSRQGDESWTVASAKAKLSEVIERAQSAPQTITRNGKPSVVVVSAEEWQRKTARKGTLAEFLMSSPLRGADLDLERQG
DEPRDPEL
Download Length: 267 bp
>AT236094 NZ_LR135309:26376-26639 [Enterococcus faecium]
ATGGAAATGTTACCTATAAAAAAATGGGGAAATAGTAATGGCCTTAGATTGCCAAAGTATATTATGGAATATCTTGGAAT
TCATACAGAAGACAAAGTGAAGATAATACAAGAAGAAGTAAACGGTCAGAAGCGGCTAATTATCGAAGCGGCTAATATAG
AAAATGAATTAACAATTGAACAGTTATTTGAAAATTACACTGATGAAAGAAATCATGTGACGATTCAAAATTTAGGTGAA
GCAGTAGGTAATGAAAAATGGTGA
ATGGAAATGTTACCTATAAAAAAATGGGGAAATAGTAATGGCCTTAGATTGCCAAAGTATATTATGGAATATCTTGGAAT
TCATACAGAAGACAAAGTGAAGATAATACAAGAAGAAGTAAACGGTCAGAAGCGGCTAATTATCGAAGCGGCTAATATAG
AAAATGAATTAACAATTGAACAGTTATTTGAAAATTACACTGATGAAAGAAATCATGTGACGATTCAAAATTTAGGTGAA
GCAGTAGGTAATGAAAAATGGTGA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Structures
Toxin
Source | ID | Structure |
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Antitoxin
Source | ID | Structure |
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