Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/CC2985(antitoxin)
Location 3396311..3396855 Replicon chromosome
Accession NZ_CP092436
Organism Rhizobium sp. K102

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag MHI61_RS22825 Protein ID WP_239792895.1
Coordinates 3396311..3396601 (-) Length 97 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag MHI61_RS22830 Protein ID WP_239790665.1
Coordinates 3396604..3396855 (-) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MHI61_RS22795 (MHI61_22800) 3391525..3392628 - 1104 WP_038686176.1 ABC transporter permease -
MHI61_RS22800 (MHI61_22805) 3392636..3394147 - 1512 WP_239790661.1 ABC transporter ATP-binding protein -
MHI61_RS22805 (MHI61_22810) 3394236..3395228 - 993 WP_064693372.1 BMP family ABC transporter substrate-binding protein -
MHI61_RS22810 (MHI61_22815) 3395387..3395584 + 198 WP_239790663.1 hypothetical protein -
MHI61_RS22815 (MHI61_22820) 3395646..3395963 - 318 WP_038686170.1 hypothetical protein -
MHI61_RS22825 (MHI61_22830) 3396311..3396601 - 291 WP_239792895.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
MHI61_RS22830 (MHI61_22835) 3396604..3396855 - 252 WP_239790665.1 type II toxin-antitoxin system ParD family antitoxin Antitoxin
MHI61_RS22835 (MHI61_22840) 3397071..3397271 + 201 Protein_3327 KTSC domain-containing protein -
MHI61_RS22840 (MHI61_22845) 3397604..3397828 + 225 WP_239790666.1 CrpP-related protein -
MHI61_RS22845 (MHI61_22850) 3397825..3399129 - 1305 WP_004673542.1 nicotinate phosphoribosyltransferase -
MHI61_RS22850 (MHI61_22855) 3399297..3399641 - 345 WP_239790667.1 hypothetical protein -
MHI61_RS22855 (MHI61_22860) 3399729..3400688 - 960 WP_239790668.1 glyoxylate/hydroxypyruvate reductase A -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-92)

Antitoxin

Antitoxin ParD

(3-70)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 11046.57 Da        Isoelectric Point: 6.6059

>T236090 WP_239792895.1 NZ_CP092436:c3396601-3396311 [Rhizobium sp. K102]
MGFRITEQAEEDIVGIAETGIRLFGSAHARRYHDELYAIFDLIAANPRMARERHEISPPMRIHPFKAHLVVYTIAEGDNV
LIVRIRHGHEDWSSQV

Download         Length: 291 bp

>T236090 NZ_LR135298:45704-46054 [Enterococcus faecium]
ATGGTGAGAAAACCTAGACAAGGCGATATTCTATTATTGAATACAGCACCTCGATCTGGACACGAACAGACAGGTAAAAG
ACCTTATATTGTTTTAAGTCATGATATTATTGCGGATTATAGTAACGTTGTTACAGTTGCTCCAATTTCTAGTACAACTA
GAAACTATCCGCTATATGTAAATATAAACTCAGAATATGAAATGAAGACAACAGGAAAAGTATTATTAGATCAACTAACG
ACAATTGATTATGAAGCCAGAGAGTGTATTTTTTTGGAAAAAGCGCATGATAGTTTAGTTGAGGAGTTATTGATGAAAGT
TAGAACAGTTTTTCAAAAAGTAAGCAAATAA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9396.49 Da        Isoelectric Point: 8.4694

>AT236090 WP_239790665.1 NZ_CP092436:c3396855-3396604 [Rhizobium sp. K102]
MATMNVSLPDPMKDWVEAQTKTGRYANASDYVRDLIRKDQERNDKIAAMQRYVDEGLKSGVGSRSKDELFEAARARLESS
RGN

Download         Length: 252 bp

>AT236090 NZ_LR135298:45447-45710 [Enterococcus faecium]
ATGGAAATGTTACCTATAAAAAAATGGGGAAATAGTAATGGCCTTAGATTGCCAAAGTATATTATGGAATATCTTGGAAT
TCATACAGAAGACAAAGTGAAGATAATACAAGAAGAAGTAAACGGTCAGAAGCGGCTAATTATCGAAGCGGCTAATATAG
AAAATGAATTAACAATTGAACAGTTATTTGAAAATTACACTGATGAAAGAAATCATGTGACGATTCAAAATTTAGGTGAA
GCAGTAGGTAATGAAAAATGGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References