Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | unclassified/Polyketide_cyc2(toxin) |
| Location | 4992411..4993076 | Replicon | chromosome |
| Accession | NZ_CP092423 | ||
| Organism | Mycobacterium lentiflavum strain ATCC 51985 | ||
Toxin (Protein)
| Gene name | novel[antitoxin] | Uniprot ID | - |
| Locus tag | MJO58_RS23140 | Protein ID | WP_090606268.1 |
| Coordinates | 4992411..4992884 (-) | Length | 158 a.a. |
Antitoxin (Protein)
| Gene name | novel[toxin] | Uniprot ID | - |
| Locus tag | MJO58_RS23145 | Protein ID | WP_239721117.1 |
| Coordinates | 4992888..4993076 (-) | Length | 63 a.a. |
Genomic Context
Location: 4987414..4988646 (1233 bp)
Type: Others
Protein ID: WP_239721112.1
Type: Others
Protein ID: WP_239721112.1
Location: 4988648..4990174 (1527 bp)
Type: Others
Protein ID: WP_239721114.1
Type: Others
Protein ID: WP_239721114.1
Location: 4990212..4990697 (486 bp)
Type: Others
Protein ID: WP_090606260.1
Type: Others
Protein ID: WP_090606260.1
Location: 4997225..4997755 (531 bp)
Type: Others
Protein ID: WP_259608725.1
Type: Others
Protein ID: WP_259608725.1
Location: 4990702..4991136 (435 bp)
Type: Others
Protein ID: WP_090606263.1
Type: Others
Protein ID: WP_090606263.1
Location: 4991192..4992430 (1239 bp)
Type: Others
Protein ID: WP_239721116.1
Type: Others
Protein ID: WP_239721116.1
Location: 4992411..4992884 (474 bp)
Type: Toxin
Protein ID: WP_090606268.1
Type: Toxin
Protein ID: WP_090606268.1
Location: 4992888..4993076 (189 bp)
Type: Antitoxin
Protein ID: WP_239721117.1
Type: Antitoxin
Protein ID: WP_239721117.1
Location: 4993219..4995603 (2385 bp)
Type: Others
Protein ID: WP_239721118.1
Type: Others
Protein ID: WP_239721118.1
Location: 4995600..4997180 (1581 bp)
Type: Others
Protein ID: WP_239721119.1
Type: Others
Protein ID: WP_239721119.1
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Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| MJO58_RS23115 (MJO58_23065) | 4987414..4988646 | + | 1233 | WP_239721112.1 | acetyl-CoA acetyltransferase | - |
| MJO58_RS23120 (MJO58_23070) | 4988648..4990174 | + | 1527 | WP_239721114.1 | carotenoid oxygenase family protein | - |
| MJO58_RS23125 (MJO58_23075) | 4990212..4990697 | + | 486 | WP_090606260.1 | VOC family protein | - |
| MJO58_RS23130 (MJO58_23080) | 4990702..4991136 | - | 435 | WP_090606263.1 | hypothetical protein | - |
| MJO58_RS23135 (MJO58_23085) | 4991192..4992430 | - | 1239 | WP_239721116.1 | cyclopropane-fatty-acyl-phospholipid synthase family protein | - |
| MJO58_RS23140 (MJO58_23090) | 4992411..4992884 | - | 474 | WP_090606268.1 | SRPBCC family protein | Toxin |
| MJO58_RS23145 (MJO58_23095) | 4992888..4993076 | - | 189 | WP_239721117.1 | antitoxin | Antitoxin |
| MJO58_RS23150 (MJO58_23100) | 4993219..4995603 | - | 2385 | WP_239721118.1 | cation-translocating P-type ATPase | - |
| MJO58_RS23155 (MJO58_23105) | 4995600..4997180 | - | 1581 | WP_239721119.1 | serine hydrolase | - |
| MJO58_RS23160 (MJO58_23110) | 4997225..4997755 | + | 531 | WP_259608725.1 | G/U mismatch-specific DNA glycosylase | - |
Associated MGEs
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MGE detail | Similar MGEs | Relative position | MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| No matching records found | |||||||
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 158 a.a. Molecular weight: 17034.65 Da Isoelectric Point: 9.5157
>T236076 WP_090606268.1 NZ_CP092423:c4992884-4992411 [Mycobacterium lentiflavum]
MAKLSGSIDVPLSPEQAWKHASDLSRYQDWLSIHRVWRSKLPDDLQKGTIIESIVEVKGMLNRIKWTIVHYKPPEAMTLN
GDGVGGVKVKLLAKVKPKDDGSVVSFDVHLGGPALFGPIGMIVAAALRSDIDESLERFVTVFTAPDPGRNGHGGAGR
MAKLSGSIDVPLSPEQAWKHASDLSRYQDWLSIHRVWRSKLPDDLQKGTIIESIVEVKGMLNRIKWTIVHYKPPEAMTLN
GDGVGGVKVKLLAKVKPKDDGSVVSFDVHLGGPALFGPIGMIVAAALRSDIDESLERFVTVFTAPDPGRNGHGGAGR
Download Length: 474 bp
>T236076 NZ_LR135278:2642089-2642430 [Enterococcus faecium]
GTGTCAGAAGAAAGAATTTATATTCCTAAAAAAGGTGATATTGTATGGATTGATTTTGATCCCTCCGTAGGAAAAGAAAT
TCAAAAAAGACGACCAGGACTAGTCGTCTCTCGTTATGAATTTAACCGTAAAACAATGTTTTCGGTCATATGTCCAATTA
CTTCCACTATAAAGAATTTACCGACACGTTACTCATTACCTGAAGAGCTAGATATAAAAGGACAAGTAATTATTACACAA
TTAAAATCTCTTGATTTTAAGGAACGAAAACTCAAAAAAATAGAAAACTTACCATTGCAAGACATGGCTAAAATTGATCA
GATTATACAGTATATGTTTTAA
GTGTCAGAAGAAAGAATTTATATTCCTAAAAAAGGTGATATTGTATGGATTGATTTTGATCCCTCCGTAGGAAAAGAAAT
TCAAAAAAGACGACCAGGACTAGTCGTCTCTCGTTATGAATTTAACCGTAAAACAATGTTTTCGGTCATATGTCCAATTA
CTTCCACTATAAAGAATTTACCGACACGTTACTCATTACCTGAAGAGCTAGATATAAAAGGACAAGTAATTATTACACAA
TTAAAATCTCTTGATTTTAAGGAACGAAAACTCAAAAAAATAGAAAACTTACCATTGCAAGACATGGCTAAAATTGATCA
GATTATACAGTATATGTTTTAA
Antitoxin
Download Length: 63 a.a. Molecular weight: 6684.32 Da Isoelectric Point: 4.3939
>AT236076 WP_239721117.1 NZ_CP092423:c4993076-4992888 [Mycobacterium lentiflavum]
MGFLDKAKDLLAQNADKVETAIDKAGEFVDDKTEGKYSDTIHKVAEEAKKAAASQAQGDQQD
MGFLDKAKDLLAQNADKVETAIDKAGEFVDDKTEGKYSDTIHKVAEEAKKAAASQAQGDQQD
Download Length: 189 bp
>AT236076 NZ_LR135278:2641859-2642089 [Enterococcus faecium]
ATGCTTGTTACAAAATCTAGATTACAAGGAAGTTCTGTAGTGGTAACTTTACCTTCTGATAACGGAAAGAAACCTTCAGA
AAACCAAGAATATATCGTTGTGTATTCTGATGATGGAACAATTACGTTAGTTCCAAAAATTGAAGATCCATTTAGTGGTG
GGGAAGAGGCCGAGTATTATGAGAAAGACGAATGGGAAGATTTAACTCCTGAAGGGAGAGAAATTTTATAG
ATGCTTGTTACAAAATCTAGATTACAAGGAAGTTCTGTAGTGGTAACTTTACCTTCTGATAACGGAAAGAAACCTTCAGA
AAACCAAGAATATATCGTTGTGTATTCTGATGATGGAACAATTACGTTAGTTCCAAAAATTGAAGATCCATTTAGTGGTG
GGGAAGAGGCCGAGTATTATGAGAAAGACGAATGGGAAGATTTAACTCCTGAAGGGAGAGAAATTTTATAG