Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | vapBC/PIN(toxin) |
| Location | 124953..125644 | Replicon | chromosome |
| Accession | NZ_CP092423 | ||
| Organism | Mycobacterium lentiflavum strain ATCC 51985 | ||
Toxin (Protein)
| Gene name | vapC | Uniprot ID | - |
| Locus tag | MJO58_RS00610 | Protein ID | WP_239721677.1 |
| Coordinates | 124953..125393 (-) | Length | 147 a.a. |
Antitoxin (Protein)
| Gene name | vapB | Uniprot ID | - |
| Locus tag | MJO58_RS00615 | Protein ID | WP_239721679.1 |
| Coordinates | 125390..125644 (-) | Length | 85 a.a. |
Genomic Context
Location: 122249..122857 (609 bp)
Type: Others
Protein ID: WP_239721672.1
Type: Others
Protein ID: WP_239721672.1
Location: 123084..124028 (945 bp)
Type: Others
Protein ID: WP_239721674.1
Type: Others
Protein ID: WP_239721674.1
Location: 125851..126705 (855 bp)
Type: Others
Protein ID: WP_239721680.1
Type: Others
Protein ID: WP_239721680.1
Location: 120899..121282 (384 bp)
Type: Others
Protein ID: WP_239723475.1
Type: Others
Protein ID: WP_239723475.1
Location: 121322..121618 (297 bp)
Type: Others
Protein ID: Protein_113
Type: Others
Protein ID: Protein_113
Location: 121672..122148 (477 bp)
Type: Others
Protein ID: WP_239721671.1
Type: Others
Protein ID: WP_239721671.1
Location: 124289..124783 (495 bp)
Type: Others
Protein ID: WP_239721675.1
Type: Others
Protein ID: WP_239721675.1
Location: 124953..125393 (441 bp)
Type: Toxin
Protein ID: WP_239721677.1
Type: Toxin
Protein ID: WP_239721677.1
Location: 125390..125644 (255 bp)
Type: Antitoxin
Protein ID: WP_239721679.1
Type: Antitoxin
Protein ID: WP_239721679.1
Location: 126718..128001 (1284 bp)
Type: Others
Protein ID: WP_239721682.1
Type: Others
Protein ID: WP_239721682.1
Location: 128013..129842 (1830 bp)
Type: Others
Protein ID: WP_239721684.1
Type: Others
Protein ID: WP_239721684.1
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Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| MJO58_RS00580 (MJO58_00580) | 120899..121282 | - | 384 | WP_239723475.1 | DUF4267 domain-containing protein | - |
| MJO58_RS00585 (MJO58_00585) | 121322..121618 | - | 297 | Protein_113 | NIPSNAP family protein | - |
| MJO58_RS00590 (MJO58_00590) | 121672..122148 | - | 477 | WP_239721671.1 | DUF1772 domain-containing protein | - |
| MJO58_RS00595 (MJO58_00595) | 122249..122857 | + | 609 | WP_239721672.1 | TetR/AcrR family transcriptional regulator | - |
| MJO58_RS00600 (MJO58_00600) | 123084..124028 | + | 945 | WP_239721674.1 | NADP-dependent oxidoreductase | - |
| MJO58_RS00605 (MJO58_00605) | 124289..124783 | - | 495 | WP_239721675.1 | MarR family transcriptional regulator | - |
| MJO58_RS00610 (MJO58_00610) | 124953..125393 | - | 441 | WP_239721677.1 | type II toxin-antitoxin system VapC family toxin | Toxin |
| MJO58_RS00615 (MJO58_00615) | 125390..125644 | - | 255 | WP_239721679.1 | antitoxin | Antitoxin |
| MJO58_RS00620 (MJO58_00620) | 125851..126705 | + | 855 | WP_239721680.1 | thioesterase family protein | - |
| MJO58_RS00625 (MJO58_00625) | 126718..128001 | - | 1284 | WP_239721682.1 | hypothetical protein | - |
| MJO58_RS00630 (MJO58_00630) | 128013..129842 | - | 1830 | WP_239721684.1 | S8 family peptidase | - |
Associated MGEs
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MGE detail | Similar MGEs | Relative position | MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| No matching records found | |||||||
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 147 a.a. Molecular weight: 15690.89 Da Isoelectric Point: 6.3699
>T236075 WP_239721677.1 NZ_CP092423:c125393-124953 [Mycobacterium lentiflavum]
MKIVDANVLLYAVNSAAEHHNASRRWLDNALSGADTVGLAWVPLLAFVRLTTKIGLFPAPLHPADAMRQVEQWCGAPGAV
VIGPTERHPQQLGGLLSHIGTGGNLVNDAHLAALALEHRAGIVSYDNDFGRFDGVRWDTPDTLLMP
MKIVDANVLLYAVNSAAEHHNASRRWLDNALSGADTVGLAWVPLLAFVRLTTKIGLFPAPLHPADAMRQVEQWCGAPGAV
VIGPTERHPQQLGGLLSHIGTGGNLVNDAHLAALALEHRAGIVSYDNDFGRFDGVRWDTPDTLLMP
Download Length: 441 bp
>T236075 NZ_LR135278:2302406-2302672 [Enterococcus faecium]
ATGAGTAACTATACAGTCGCAATCAAAAACTCTGCGAAAGTGGATTTAAGAAAAATCAAGCAAACGAATTTAAAGAAACA
ATTTGAAGAAGTGATTCAGACATTGAAGGAAGATCCATATATGCCCACGCAGTCTTTTGAAAAGCTGAGACCTACACATG
AAGGCAGATACTCACGCAGGCTGAATAGACAGCATCGAGTGGTTTACAAAGTTGATGAGGAAAATAAAGTTGTAGAAATT
TATTCTGCCTGGACACATTATGAGTGA
ATGAGTAACTATACAGTCGCAATCAAAAACTCTGCGAAAGTGGATTTAAGAAAAATCAAGCAAACGAATTTAAAGAAACA
ATTTGAAGAAGTGATTCAGACATTGAAGGAAGATCCATATATGCCCACGCAGTCTTTTGAAAAGCTGAGACCTACACATG
AAGGCAGATACTCACGCAGGCTGAATAGACAGCATCGAGTGGTTTACAAAGTTGATGAGGAAAATAAAGTTGTAGAAATT
TATTCTGCCTGGACACATTATGAGTGA
Antitoxin
Download Length: 85 a.a. Molecular weight: 9349.56 Da Isoelectric Point: 7.0161
>AT236075 WP_239721679.1 NZ_CP092423:c125644-125390 [Mycobacterium lentiflavum]
VRTTVTLDDDTLALVRRRMRERGVSFKQALNDAIRDGAHGRPAPTPFETTVADLGVPAVNLDRALQLAAELEDEELLRRQ
RRGA
VRTTVTLDDDTLALVRRRMRERGVSFKQALNDAIRDGAHGRPAPTPFETTVADLGVPAVNLDRALQLAAELEDEELLRRQ
RRGA
Download Length: 255 bp
>AT236075 NZ_LR135278:2302143-2302406 [Enterococcus faecium]
ATGGCTAATACAACGATGAATCCTAGCACTGCTCGTAAAAATTTTTATCAGTTATTGAAAGAGGTAAATGAAAATCATAC
TGAAATCGAGATTATTAGTGATCGTAGTGGAAACAATGCTGTATTGATTGGGCTGGAAGACTGGAGAGCGATTCAAGAAA
CCCTTTTTCTTGAGCAAACAGGTACTTTAGATAAAGTACGAGACCGCGAAAAAGACGACAGTAGCTTTACGAATATCGAT
GATATTGATTGGGAAGCTCTTTGA
ATGGCTAATACAACGATGAATCCTAGCACTGCTCGTAAAAATTTTTATCAGTTATTGAAAGAGGTAAATGAAAATCATAC
TGAAATCGAGATTATTAGTGATCGTAGTGGAAACAATGCTGTATTGATTGGGCTGGAAGACTGGAGAGCGATTCAAGAAA
CCCTTTTTCTTGAGCAAACAGGTACTTTAGATAAAGTACGAGACCGCGAAAAAGACGACAGTAGCTTTACGAATATCGAT
GATATTGATTGGGAAGCTCTTTGA