Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | /BrnT(toxin) |
| Location | 6813838..6814321 | Replicon | chromosome |
| Accession | NZ_CP092417 | ||
| Organism | Endozoicomonas sp. SCSIO W0465 | ||
Toxin (Protein)
| Gene name | - | Uniprot ID | - |
| Locus tag | MJO57_RS30805 | Protein ID | WP_252021272.1 |
| Coordinates | 6814049..6814321 (-) | Length | 91 a.a. |
Antitoxin (Protein)
| Gene name | - | Uniprot ID | - |
| Locus tag | MJO57_RS30800 | Protein ID | WP_252021270.1 |
| Coordinates | 6813838..6814059 (-) | Length | 74 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| MJO57_RS32980 | 6809635..6809769 | + | 135 | WP_256492856.1 | hypothetical protein | - |
| MJO57_RS30785 (MJO57_30655) | 6809827..6810420 | - | 594 | WP_252021264.1 | AAA family ATPase | - |
| MJO57_RS30790 (MJO57_30660) | 6810417..6812621 | - | 2205 | WP_252021266.1 | glycosyltransferase family 2 protein | - |
| MJO57_RS30795 (MJO57_30665) | 6812761..6813582 | - | 822 | WP_252021268.1 | UTP--glucose-1-phosphate uridylyltransferase GalU | - |
| MJO57_RS30800 (MJO57_30670) | 6813838..6814059 | - | 222 | WP_252021270.1 | BrnA antitoxin family protein | Antitoxin |
| MJO57_RS30805 (MJO57_30675) | 6814049..6814321 | - | 273 | WP_252021272.1 | BrnT family toxin | Toxin |
| MJO57_RS30810 (MJO57_30680) | 6814480..6815400 | - | 921 | WP_252021282.1 | nucleotide sugar dehydrogenase | - |
| MJO57_RS30815 (MJO57_30685) | 6815583..6815906 | - | 324 | WP_252021285.1 | transposase | - |
| MJO57_RS30820 (MJO57_30690) | 6815955..6816881 | + | 927 | WP_252021287.1 | transposase | - |
| MJO57_RS30825 (MJO57_30695) | 6816931..6817611 | + | 681 | WP_252021289.1 | transposase | - |
| MJO57_RS30830 (MJO57_30700) | 6817616..6818677 | - | 1062 | WP_252021291.1 | ISNCY family transposase | - |
| MJO57_RS30835 (MJO57_30705) | 6818817..6819086 | - | 270 | Protein_6129 | UDP-glucose 6-dehydrogenase | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 91 a.a. Molecular weight: 10423.83 Da Isoelectric Point: 7.8857
>T236068 WP_252021272.1 NZ_CP092417:c6814321-6814049 [Endozoicomonas sp. SCSIO W0465]
MGKTRFEYDIAKSHANRDKHGIDFDEATALWEDSNLVCLPSTVKTDELRLLFIGQIKSKHWTAIATQRGECLRIISVRRS
RKNEVDLYES
MGKTRFEYDIAKSHANRDKHGIDFDEATALWEDSNLVCLPSTVKTDELRLLFIGQIKSKHWTAIATQRGECLRIISVRRS
RKNEVDLYES
Download Length: 273 bp
>T236068 NZ_LR135256:125570-126433 [Enterococcus faecium]
ATGGCAAATATAGTCAATTTTACTGACAAACAATTTGAGAATCGCTTAAATGATAATTTAGAAGAATTGATTCAAGGAAA
AAAAGCGGTTGAATCGCCAACCGCTTTTTTACTTGGTGGGCAACCAGGGTCAGGGAAAACCAGTTTGCGATCAGCAATTT
TTGAAGAAACACAAGGGAATGTTATTGTCATTGATAATGATACCTTTAAACAACAGCACCCTAATTTTGATGAACTAGTG
AAACTTTATGAAAAAGACGTAGTAAAACACGTTACCCCTTATTCTAATCGCATGACAGAAGCGATCATAAGCCGTTTGAG
CGATCAAGGGTATAATTTGGTGATCGAAGGTACAGGACGAACAACAGACGTTCCTATTCAAACCGCAACAATGCTTCAAG
CCAAAGGTTATGAAACAAAAATGTATGTCATGGCAGTACCTAAAATCAACTCATATTTAGGAACAATTGAACGATATGAA
ACCATGTATGCAGATGATCCAATGACAGCCAGGGCAACACCAAAACAAGCGCATGATATTGTTGTCAAAAACTTACCGAC
CAATTTAGAAACCCTTCATAAAACGGGCTTATTTAGCGATATAAGGCTATATAACAGAGAAGGAGTAAAACTCTATTCAA
GTTTGGAAACACCTTCTATTAGTCCAAAAGAAACCTTAGAAAAAGAATTGAATCGTAAAGTATCAGGGAAAGAAATTCAA
CCGACTTTAGAACGAATAGAGCAAAAAATGGTTCTAAATAAACACCAAGAGACACCTGAATTTAAAGCAATTCAACAAAA
ATTGGAAAGCTTGCAGCCACCTACACCACCAATACCCAAAACACCTAAACTTCCAGGTATTTAA
ATGGCAAATATAGTCAATTTTACTGACAAACAATTTGAGAATCGCTTAAATGATAATTTAGAAGAATTGATTCAAGGAAA
AAAAGCGGTTGAATCGCCAACCGCTTTTTTACTTGGTGGGCAACCAGGGTCAGGGAAAACCAGTTTGCGATCAGCAATTT
TTGAAGAAACACAAGGGAATGTTATTGTCATTGATAATGATACCTTTAAACAACAGCACCCTAATTTTGATGAACTAGTG
AAACTTTATGAAAAAGACGTAGTAAAACACGTTACCCCTTATTCTAATCGCATGACAGAAGCGATCATAAGCCGTTTGAG
CGATCAAGGGTATAATTTGGTGATCGAAGGTACAGGACGAACAACAGACGTTCCTATTCAAACCGCAACAATGCTTCAAG
CCAAAGGTTATGAAACAAAAATGTATGTCATGGCAGTACCTAAAATCAACTCATATTTAGGAACAATTGAACGATATGAA
ACCATGTATGCAGATGATCCAATGACAGCCAGGGCAACACCAAAACAAGCGCATGATATTGTTGTCAAAAACTTACCGAC
CAATTTAGAAACCCTTCATAAAACGGGCTTATTTAGCGATATAAGGCTATATAACAGAGAAGGAGTAAAACTCTATTCAA
GTTTGGAAACACCTTCTATTAGTCCAAAAGAAACCTTAGAAAAAGAATTGAATCGTAAAGTATCAGGGAAAGAAATTCAA
CCGACTTTAGAACGAATAGAGCAAAAAATGGTTCTAAATAAACACCAAGAGACACCTGAATTTAAAGCAATTCAACAAAA
ATTGGAAAGCTTGCAGCCACCTACACCACCAATACCCAAAACACCTAAACTTCCAGGTATTTAA
Antitoxin
Download Length: 74 a.a. Molecular weight: 8423.55 Da Isoelectric Point: 4.7683
>AT236068 WP_252021270.1 NZ_CP092417:c6814059-6813838 [Endozoicomonas sp. SCSIO W0465]
MKAEDIDKKFDSGEDVLEYFDTDNPLRPNLEAKRVNIDFPAWVVNALDKEANAIGISRQALIKTWIVDRIRHP
MKAEDIDKKFDSGEDVLEYFDTDNPLRPNLEAKRVNIDFPAWVVNALDKEANAIGISRQALIKTWIVDRIRHP
Download Length: 222 bp
>AT236068 NZ_LR135256:125296-125568 [Enterococcus faecium]
ATGGCAGTTACGTATGAAAAAACATTTGAAATAGAGATCATTAACGAATTATCGGCAAGCGTTTATAATCGAGTATTAAA
CTATGTTTTGAACCATGAATTAAATAAAAATGACTCTCAATTATTGGAAGTCAATTTATTAAACCAATTAAAGCTTGCAA
AACGTGTAAATCTTTTTGATTATTCTTTAGAAGAATTACAAGCCGTTCATGAGTATTGGCGGTCAATGAATCGTTACTCA
AAACAAGTTTTGAATAAAGAGAAAGTGGCTTAA
ATGGCAGTTACGTATGAAAAAACATTTGAAATAGAGATCATTAACGAATTATCGGCAAGCGTTTATAATCGAGTATTAAA
CTATGTTTTGAACCATGAATTAAATAAAAATGACTCTCAATTATTGGAAGTCAATTTATTAAACCAATTAAAGCTTGCAA
AACGTGTAAATCTTTTTGATTATTCTTTAGAAGAATTACAAGCCGTTCATGAGTATTGGCGGTCAATGAATCGTTACTCA
AAACAAGTTTTGAATAAAGAGAAAGTGGCTTAA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
Structures
Toxin
| Source | ID | Structure |
|---|
Antitoxin
| Source | ID | Structure |
|---|