Detailed information of TA system TA236067

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): parDE/ParE-RHH
• Location: 6411240..6411799
• Replicon: chromosome
• Accession: NZ_CP092417
• Organism: Endozoicomonas sp. SCSIO W0465

Toxin (Protein)

• Gene name: parE
• Uniprot ID: -
• Locus tag: MJO57_RS28815
• Protein ID: WP_252020685.1
• Coordinates: 6411240..6411560 (-)
• Length: 107 a.a.

Antitoxin (Protein)

• Gene name: parD
• Uniprot ID: -
• Locus tag: MJO57_RS28820
• Protein ID: WP_252020687.1
• Coordinates: 6411557..6411799 (-)
• Length: 81 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
MJO57_RS28785 (MJO57_28665)	6408103..6408585	-	483	WP_252020675.1	hypothetical protein	-
MJO57_RS28790 (MJO57_28670)	6408619..6409710	-	1092	WP_252020677.1	hypothetical protein	-
MJO57_RS28795 (MJO57_28675)	6409686..6410108	-	423	WP_252020679.1	hypothetical protein	-
MJO57_RS28800 (MJO57_28680)	6410048..6410296	-	249	WP_066017877.1	hypothetical protein	-
MJO57_RS28805 (MJO57_28685)	6410299..6410706	-	408	WP_252020681.1	3TM-type holin	-
MJO57_RS28810 (MJO57_28690)	6410699..6411097	-	399	WP_252020683.1	M15 family metallopeptidase	-
MJO57_RS28815 (MJO57_28695)	6411240..6411560	-	321	WP_252020685.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
MJO57_RS28820 (MJO57_28700)	6411557..6411799	-	243	WP_252020687.1	type II toxin-antitoxin system ParD family antitoxin	Antitoxin
MJO57_RS28825 (MJO57_28705)	6411874..6412401	-	528	WP_252020689.1	hypothetical protein	-
MJO57_RS28830 (MJO57_28710)	6412482..6412655	-	174	WP_252020691.1	hypothetical protein	-
MJO57_RS28835 (MJO57_28715)	6412676..6412945	-	270	WP_252020694.1	Ref family recombination enhancement nuclease	-
MJO57_RS28840 (MJO57_28720)	6412956..6413360	-	405	WP_252020696.1	hypothetical protein	-
MJO57_RS28845 (MJO57_28725)	6413393..6413893	-	501	WP_252020698.1	DUF1367 family protein	-
MJO57_RS28850 (MJO57_28730)	6413893..6414465	-	573	WP_252020700.1	hypothetical protein	-
MJO57_RS28855 (MJO57_28735)	6414398..6414940	-	543	WP_252020702.1	hypothetical protein	-
MJO57_RS28860 (MJO57_28740)	6415014..6416528	-	1515	WP_252020703.1	IS66 family transposase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	-	6376127..6421801	45674

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (5-92)

Antitoxin

• Antitoxin ParD (1-78)

Sequences

Toxin

Protein

• Length: 107 a.a.
• Molecular weight: 12583.48 Da
• Isoelectric Point: 10.0365

>T236067 WP_252020685.1 NZ_CP092417:c6411560-6411240 [Endozoicomonas sp. SCSIO W0465]
MNTFELTWKAVSDLKDIARYTIKRWGRLQRNHYLKQLDDTFHRLAESPMTGKPCDNIRPGYRKFPQGSHIVFYRQIGLTH
IQVVRILHKSMDVEQHLTTDLDSKCQ

Nucleotide

• Length: 321 bp

>T236067 NZ_LR135255:147256-147597 [Enterococcus faecium]
ATGACTGAAGAAAAAAATTACATTCCTAAAAAGGGAGATATTGTTTGGATTGATTTTGATCCTTCTGCAGGAAAAGAGAT
TCAAAAGCGGCGTCCTGGATTAGTTGTTTCTAGATACGAGTTTAATCGCAAAACAATGTTTGCAGTTATTTGTCCGATTA
CCTCTACTATAAGAAATTTTCCGACACGCTATTCATTACCTACCGAATTAGACACTACTGGACAAATACTTATTTCTCAA
TTGAAGTCGCTCGATTTCAATGAGAGAAAACTTAAAAAAATTGAATCCTTACCTTTACAAGATATGGCGAAAATCGATCA
AATGATTGAATATATATTTTAA

Antitoxin

Protein

• Length: 81 a.a.
• Molecular weight: 8961.84 Da
• Isoelectric Point: 4.0533

>AT236067 WP_252020687.1 NZ_CP092417:c6411799-6411557 [Endozoicomonas sp. SCSIO W0465]
MSRNTSITLGDHFDGFIASQIESGRYGSASEVVRAALRLLENRENKLTILRNLLIEGEQSEAADYDYQSLIDEVDSELPE

Nucleotide

• Length: 243 bp

>AT236067 NZ_LR135255:147026-147256 [Enterococcus faecium]
ATGCTTATTACAAAATCTAGATTACAAGGAAGTTCTGTAGTGATTACTTTGCCTTCTGATAACGGAAAGAAGCCTTCGGA
AAATAAAGAATATATAGTTATCTATTCTGATGATGGAACAATTACTTTGGTTCCAAAAATTGAAGATCCATTTAGTGGTG
GAGAAGAAGCGGAGTATTACGAAAAAGATGAATGGGAAGATTTGTCTCCTGAAGGAAGAGAGATTTTATAA