236060

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type VII Classification (family/domain) HepT-MntA/HepT(toxin)
Location 1203152..1203971 Replicon chromosome
Accession NZ_CP092417
Organism Endozoicomonas sp. SCSIO W0465

Toxin (Protein)


Gene name hepT Uniprot ID -
Locus tag MJO57_RS05180 Protein ID WP_252023482.1
Coordinates 1203152..1203574 (-) Length 141 a.a.

Antitoxin (Protein)


Gene name mntA Uniprot ID -
Locus tag MJO57_RS05185 Protein ID WP_252023484.1
Coordinates 1203567..1203971 (-) Length 135 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MJO57_RS05145 (MJO57_05115) 1198729..1199262 + 534 WP_252023473.1 hypothetical protein -
MJO57_RS05150 (MJO57_05120) 1199432..1199764 - 333 Protein_1017 DUF6444 domain-containing protein -
MJO57_RS05155 (MJO57_05125) 1199820..1201478 + 1659 WP_252017470.1 transposase -
MJO57_RS05160 (MJO57_05130) 1201635..1202063 + 429 WP_252023475.1 hypothetical protein -
MJO57_RS05165 (MJO57_05135) 1202129..1202344 - 216 WP_252023477.1 DUF3368 domain-containing protein -
MJO57_RS05170 (MJO57_05140) 1202437..1202679 - 243 WP_252023479.1 hypothetical protein -
MJO57_RS05175 (MJO57_05145) 1202799..1203035 - 237 WP_252023480.1 UPF0175 family protein -
MJO57_RS05180 (MJO57_05150) 1203152..1203574 - 423 WP_252023482.1 DUF86 domain-containing protein Toxin
MJO57_RS05185 (MJO57_05155) 1203567..1203971 - 405 WP_252023484.1 nucleotidyltransferase domain-containing protein Antitoxin
MJO57_RS05190 (MJO57_05160) 1204086..1204229 - 144 WP_252023486.1 DUF433 domain-containing protein -
MJO57_RS05195 (MJO57_05165) 1204965..1207082 - 2118 WP_252023488.1 alpha-galactosidase -
MJO57_RS05200 (MJO57_05170) 1207173..1208534 - 1362 WP_252023490.1 melibiose:sodium transporter MelB -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Ribonuclease HepT-like

(13-130)

Antitoxin

Polymerase beta, nucleotidyltransferase

(21-98)


Sequences

Toxin        


Download         Length: 141 a.a.        Molecular weight: 15883.20 Da        Isoelectric Point: 6.0781

>T236060 WP_252023482.1 NZ_CP092417:c1203574-1203152 [Endozoicomonas sp. SCSIO W0465]
MNDIILNKYSIIQRCIARINEEYKGHESELATNYTQQDSIILNIQRACQAAQDMANYVIKLKKLGIPQNARESFQLLNDH
GLVSAPLTVSMIKMVGFRNIAVHEYQKLNIAILKSVIENHVDEINGFAEEVMCSFNNDGQ

Download         Length: 423 bp

>T236060 NZ_LR135244:17181-17531 [Enterococcus faecium]
ATGGTGAGAAAACCTAGACAAGGCGATATTCTATTATTGAATACAGCACCTCGATCTGGACACGAACAGACAGGTAAAAG
ACCTTATATTGTTTTAAGTCATGATATTATTGCGGATTATAGTAACGTTGTTACAGTTGCTCCAATTTCTAGTACAACTA
GAAACTATCCGCTATATGTAAATATAAACTCAGAATATGAAATGAAGACAACAGGAAAAGTATTATTAGATCAACTAACG
ACAATTGATTATGAAGCCAGAGAGTGTATTTTTTTGGAAAAAGCGCATGATAGTTTAGTTGAGGAGTTATTGATGAAAGT
TAGAACAGTTTTTCAAAAAGTAAGCAAATAA

Antitoxin


Download         Length: 135 a.a.        Molecular weight: 15274.40 Da        Isoelectric Point: 4.1765

>AT236060 WP_252023484.1 NZ_CP092417:c1203971-1203567 [Endozoicomonas sp. SCSIO W0465]
MEPLCKAVIVSFLRQAYGDLLQGILLFGSHANGTANKESDIDLGILIDGMADPVELWENAQTLASQVNTNIDLIDLRAAT
TVLQHEVINTGLWLWQQDTLTCDLFELQVMSLYQQLQYDRREILDDLKRRLRNE

Download         Length: 405 bp

>AT236060 NZ_LR135244:16924-17187 [Enterococcus faecium]
ATGGAAATGTTACCTATAAAAAAATGGGGAAATAGTAATGGCCTTAGATTGCCAAAGTATATTATGGAATATCTTGGAAT
TCATACAGAAGACAAAGTGAAGATAATACAAGAAGAAGTAAACGGTCAGAAGCGGCTAATTATCGAAGCGGCTAATATAG
AAAATGAATTAACAATTGAACAGTTATTTGAAAATTACACTGATGAAAGAAATCATGTGACGATTCAAAATTTAGGTGAA
GCAGTAGGTAATGAAAAATGGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References