Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) rlegTA/AbiEii-AbiEi
Location 3627905..3629424 Replicon chromosome
Accession NZ_CP092382
Organism Xanthomonas oryzae strain PXO339

Toxin (Protein)


Gene name rlegT Uniprot ID A0A0K0GMB6
Locus tag MJJ08_RS17030 Protein ID WP_011259680.1
Coordinates 3627905..3628828 (-) Length 308 a.a.

Antitoxin (Protein)


Gene name rlegA Uniprot ID A0A854CLN1
Locus tag MJJ08_RS17035 Protein ID WP_011409027.1
Coordinates 3628825..3629424 (-) Length 200 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MJJ08_RS17005 (MJJ08_16980) 3624098..3624630 + 533 Protein_3257 methyltransferase domain-containing protein -
MJJ08_RS17010 (MJJ08_16985) 3624647..3625135 - 489 WP_069959937.1 hypothetical protein -
MJJ08_RS17015 (MJJ08_16990) 3625230..3626195 + 966 Protein_3259 IS1595-like element ISXo5 family transposase -
MJJ08_RS17020 (MJJ08_16995) 3626647..3626889 - 243 WP_011409025.1 hypothetical protein -
MJJ08_RS17025 (MJJ08_17000) 3627355..3627825 + 471 WP_228329666.1 helix-turn-helix domain-containing protein -
MJJ08_RS17030 (MJJ08_17005) 3627905..3628828 - 924 WP_011259680.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein Toxin
MJJ08_RS17035 (MJJ08_17010) 3628825..3629424 - 600 WP_011409027.1 type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein Antitoxin
MJJ08_RS17040 (MJJ08_17015) 3629789..3630079 + 291 WP_228329665.1 FaeA/PapI family transcriptional regulator -
MJJ08_RS17045 (MJJ08_17020) 3630111..3630686 + 576 WP_011409029.1 BrxE family protein -
MJJ08_RS17050 (MJJ08_17025) 3630668..3631699 - 1032 WP_042465093.1 IS630 family transposase -
MJJ08_RS17055 (MJJ08_17030) 3632198..3632488 + 291 WP_011409031.1 hypothetical protein -
MJJ08_RS17060 (MJJ08_17035) 3632469..3632936 + 468 WP_181718264.1 hypothetical protein -
MJJ08_RS17070 (MJJ08_17045) 3633206..3633742 + 537 WP_011409032.1 lipocalin family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Nucleotidyl transferase AbiEii toxin, Type IV TA system

(41-269)

Antitoxin

Transcriptional regulator, AbiEi antitoxin

(7-52)


Sequences

Toxin        


Download         Length: 308 a.a.        Molecular weight: 34114.16 Da        Isoelectric Point: 5.4588

>T236027 WP_011259680.1 NZ_CP092382:c3628828-3627905 [Xanthomonas oryzae]
MNEPDKSRRTVAASVRARLLNKARAERLDFNLLLTRYALERVLYRLSVSEQQGQFLLKGALLFDIWFDIPHRPTHDADLL
GFGSTEIPHLEDLFRRISQIASDDGIVFQADSVKAAEIRKEANYAGVRVTMIGLLDGARCTVQIDIGFGDAVTPGPDNVQ
YPVILDGMPQPQLRVYPRYTVVAEKLEAMVKLGILNSRMKDYFDLWVLAGHSDFDGAVLATAIRATFECRGTAIPPGAPL
GLTDEFGLDEQKTKQWQAFLRKNTLEPMPLTTVIEALREFVLPVLAALAAGEGFDRQWRAGAGWDAA

Download         Length: 924 bp

>T236027 NZ_LR135192:92941-93282 [Enterococcus faecium]
ATGACTGAAGAAAAAAATTACATTCCTAAAAAGGGAGATATTGTTTGGATTGATTTTGATCCTTCTGCAGGAAAAGAGAT
TCAAAAGCGGCGTCCTGGATTAGTTGTTTCTAGATACGAGTTTAATCGCAAAACAATGTTTGCAGTTATTTGTCCGATTA
CCTCTACTATAAGAAATTTTCCGACACGCTATTCATTACCTACCGAATTAGACACTACTGGACAAATACTTATTTCTCAA
TTGAAGTCGCTCGATTTCAATGAGAGAAAACTTAAAAAAATTGAATCCTTACCTTTACAAGATATGGCGAAAATCGATCA
AATGATTGAATATATATTTTAA

Antitoxin


Download         Length: 200 a.a.        Molecular weight: 22037.74 Da        Isoelectric Point: 10.1240

>AT236027 WP_011409027.1 NZ_CP092382:c3629424-3628825 [Xanthomonas oryzae]
MDTTVDKLLELVRTRGLLRPHDLAPLGIPRVALTRAVRRGQLERVGRGLYGLVARPVSAHGTLAEVARRVPKGVVCLLSA
LRVHDLTTQAPFEVWLAIDNKAAAPKLDYPPLRLVRFSGPALSEGVEEHVVDGVPVHVTSVAKTVADCFKYRNKIGIDVA
LEALREAWVARRMTSDEIWHYAKIDRVANVMRPYLESLA

Download         Length: 600 bp

>AT236027 NZ_LR135192:92711-92941 [Enterococcus faecium]
ATGCTTATTACAAAATCTAGATTACAAGGAAGTTCTGTAGTGATTACTTTGCCTTCTGATAACGGAAAGAAGCCTTCGGA
AAATAAAGAATATATAGTTATCTATTCTGATGATGGAACAATTACTTTGGTTCCAAAAATTGAAGATCCATTTAGTGGTG
GAGAAGAAGCGGAGTATTACGAAAAAGATGAATGGGAAGATTTGTCTCCTGAAGGAAGAGAGATTTTATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0K0GMB6

Antitoxin

Source ID Structure
AlphaFold DB A0A854CLN1

References