236025

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pmenTA/darT(toxin)
Location 1318305..1319050 Replicon chromosome
Accession NZ_CP092382
Organism Xanthomonas oryzae strain PXO339

Toxin (Protein)


Gene name pmenT Uniprot ID -
Locus tag MJJ08_RS06345 Protein ID WP_199285672.1
Coordinates 1318721..1319050 (-) Length 110 a.a.

Antitoxin (Protein)


Gene name pmenA Uniprot ID -
Locus tag MJJ08_RS06340 Protein ID WP_011407754.1
Coordinates 1318305..1318724 (-) Length 140 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MJJ08_RS06320 (MJJ08_06320) 1314594..1314920 - 327 Protein_1203 hypothetical protein -
MJJ08_RS06325 (MJJ08_06325) 1315222..1316457 + 1236 WP_011257570.1 ISL3-like element ISXoo13 family transposase -
MJJ08_RS06330 (MJJ08_06330) 1316495..1317175 - 681 WP_011257926.1 phosphate phosphatase -
MJJ08_RS06340 (MJJ08_06340) 1318305..1318724 - 420 WP_011407754.1 macro domain-containing protein Antitoxin
MJJ08_RS06345 (MJJ08_06345) 1318721..1319050 - 330 WP_199285672.1 DUF4433 domain-containing protein Toxin
MJJ08_RS06350 (MJJ08_06350) 1319153..1320472 + 1320 WP_155296575.1 IS701-like element ISXo15 family transposase -
MJJ08_RS06355 (MJJ08_06355) 1320516..1320851 - 336 WP_011407757.1 DarT ssDNA thymidine ADP-ribosyltransferase family protein -
MJJ08_RS06360 (MJJ08_06360) 1321183..1322109 - 927 WP_011257932.1 Grx4 family monothiol glutaredoxin -
MJJ08_RS06365 (MJJ08_06365) 1322155..1322946 + 792 WP_011407758.1 polysaccharide deacetylase family protein -
MJJ08_RS06375 (MJJ08_06375) 1323248..1323919 - 672 WP_011407759.1 class I SAM-dependent methyltransferase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside IScluster/Tn - - 1315222..1320472 5250


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

ssDNA thymidine ADP-ribosyltransferase, DarT

(3-108)

Antitoxin

Macro domain

(18-130)


Sequences

Toxin        


Download         Length: 110 a.a.        Molecular weight: 13145.86 Da        Isoelectric Point: 7.1160

>T236025 WP_199285672.1 NZ_CP092382:c1319050-1318721 [Xanthomonas oryzae]
MHHVAERRWPFLFTDSHAYCQLASFYSDLSDLDKIDWPLLQARDFRRDPDDPAKFERYQAEALIHRHLPLDGLRGIVCHT
DGLKQTIERQLQERNLKLPVHTRTDWYFR

Download         Length: 330 bp

>T236025 NZ_LR135191:187233-187499 [Enterococcus faecium]
ATGAGTAACTATACAGTCGCAATCAAAAACTCTGCGAAAGTGGATTTAAGAAAAATCAAGCAAACGAATTTAAAGAAACA
ATTTGAAGAAGTGATTCAGACATTGAAGGAAGATCCATATATGCCCACGCAGTCTTTTGAAAAGCTGAGACCTACACATG
AAGGCAGATACTCACGCAGGCTGAATAGACAGCATCGAGTGGTTTACAAAGTTGATGAGGAAAATAAAGTTGTAGAAATT
TATTCTGCCTGGACACATTATGAGTGA

Antitoxin


Download         Length: 140 a.a.        Molecular weight: 15607.02 Da        Isoelectric Point: 6.4733

>AT236025 WP_011407754.1 NZ_CP092382:c1318724-1318305 [Xanthomonas oryzae]
MITFTQGNLLESGAEALVNTVNTVGVMGKGIALMFKERFKENFLRYAAACKDNQVRIGKIFVTEVNELDGPRWIINFPTK
QHWRGDSRIEWITEGLQDLHRFLIENKVKSIAIPPLGAGNGGLDWAEVRPLIEEVLGNL

Download         Length: 420 bp

>AT236025 NZ_LR135191:186970-187233 [Enterococcus faecium]
ATGGCTAATACAACGATGAATCCTAGCACTGCTCGTAAAAATTTTTATCAGTTATTGAAAGAGGTAAATGAAAATCATAC
TGAAATCGAGATTATTAGTGATCGTAGTGGAAACAATGCTGTATTGATTGGGCTGGAAGACTGGAGAGCGATTCAAGAAA
CCCTTTTTCTTGAGCAAACAGGTACTTTAGATAAAGTACGAGACCGCGAAAAAGACGACAGTAGCTTTACGAATATCGAT
GATATTGATTGGGAAGCTCTTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References