Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 655466..655816 Replicon chromosome
Accession NZ_CP092382
Organism Xanthomonas oryzae strain PXO339

Toxin (Protein)


Gene name EcnB Uniprot ID G7TLC7
Locus tag MJJ08_RS03115 Protein ID WP_011257368.1
Coordinates 655682..655816 (+) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID G7TLC8
Locus tag MJJ08_RS03110 Protein ID WP_011407410.1
Coordinates 655466..655618 (+) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MJJ08_RS03085 (MJJ08_03080) 651746..652429 - 684 WP_011257363.1 dTMP kinase -
MJJ08_RS03090 (MJJ08_03085) 652909..653451 - 543 Protein_595 GTPase -
MJJ08_RS03095 (MJJ08_03090) 653448..653903 - 456 Protein_596 hypothetical protein -
MJJ08_RS03100 (MJJ08_03095) 653895..654113 - 219 Protein_597 hypothetical protein -
MJJ08_RS03105 (MJJ08_03100) 654435..655358 + 924 WP_011407409.1 arginase -
MJJ08_RS03110 (MJJ08_03105) 655466..655618 + 153 WP_011407410.1 entericidin A/B family lipoprotein Antitoxin
MJJ08_RS03115 (MJJ08_03110) 655682..655816 + 135 WP_011257368.1 entericidin A/B family lipoprotein Toxin
MJJ08_RS03120 (MJJ08_03115) 656057..656266 + 210 WP_011407411.1 CsbD family protein -
MJJ08_RS03125 (MJJ08_03120) 656435..657724 + 1290 WP_069959696.1 tryptophan--tRNA ligase -
MJJ08_RS03130 (MJJ08_03125) 657855..658799 + 945 WP_027704118.1 MBL fold metallo-hydrolase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4457.33 Da        Isoelectric Point: 10.2040

>T236024 WP_011257368.1 NZ_CP092382:655682-655816 [Xanthomonas oryzae]
MKRAIVLLVLSMLSVGLLSGCNTVAGAGKDVKGAGEKVEDAARK

Download         Length: 135 bp

>T236024 NZ_LR135182:c108866-108594 [Enterococcus faecium]
ATGAATAACTATTCTGTGATGATTAAAAACTCGGCTAAAGCTGATTTAAAGAAAATCAAACAGTCTAATTTGAAACCTCA
ATTTGAGAAGGTTATTCAGACTTTAAAGGAAGATCCCTATCTCCCTACCCAATCATTTGAGAAGTTAAAACCTACACATG
AAGGTAGGTATTCTAGAAGATTGAATAGACAACACCGGGTTGTTTATAAGGTAGATGAAGATGAACACGTGGTTGAAATT
TATTCAGCAAGGACGCATTACGAGTCACAGTAA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5046.99 Da        Isoelectric Point: 8.7942

>AT236024 WP_011407410.1 NZ_CP092382:655466-655618 [Xanthomonas oryzae]
MKRLLTLMVLGLFSAGVMTGCNTVAGAGKDLQGAGGKVEKTAEKCSDGKC

Download         Length: 153 bp

>AT236024 NZ_LR135182:c109129-108866 [Enterococcus faecium]
ATGGCAAAAACTGTCTTAAATCCTAGCTCAGCACGGAAAAATTTTTATAAGTTGTTGAAAGATGTAAATGAGAATCATAC
GGAAATTGAAATCATTAGTGAGCGCAGTGAAAATAATGCGGTGCTTATTGGTTTGGATGATTGGAAAGCAATCAAAGAAA
CGCTATTACTTGAGCAAATAGGCACTTTGGGTGTTGTTCGTAAGCGAGAAAAAGATGATAGTGGATTTACTAATGTTGAT
GAAATTGATTGGGATAACTTATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0C5UG40

Antitoxin

Source ID Structure
AlphaFold DB A0A0C5V759

References