Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) rlegTA/AbiEii-AbiEi
Location 4098199..4099718 Replicon chromosome
Accession NZ_CP092381
Organism Xanthomonas oryzae strain HN2011

Toxin (Protein)


Gene name rlegT Uniprot ID A0A0K0GMB6
Locus tag MJJ07_RS19165 Protein ID WP_011259680.1
Coordinates 4098199..4099122 (-) Length 308 a.a.

Antitoxin (Protein)


Gene name rlegA Uniprot ID A0A854CLN1
Locus tag MJJ07_RS19170 Protein ID WP_011409027.1
Coordinates 4099119..4099718 (-) Length 200 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MJJ07_RS19140 (MJJ07_19105) 4094392..4094924 + 533 Protein_3663 methyltransferase domain-containing protein -
MJJ07_RS19145 (MJJ07_19110) 4094941..4095429 - 489 WP_011409022.1 hypothetical protein -
MJJ07_RS19150 (MJJ07_19115) 4095524..4096489 + 966 Protein_3665 IS1595-like element ISXo5 family transposase -
MJJ07_RS19155 (MJJ07_19120) 4096941..4097183 - 243 WP_011409025.1 hypothetical protein -
MJJ07_RS19160 (MJJ07_19125) 4097649..4098119 + 471 WP_228383551.1 helix-turn-helix domain-containing protein -
MJJ07_RS19165 (MJJ07_19130) 4098199..4099122 - 924 WP_011259680.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein Toxin
MJJ07_RS19170 (MJJ07_19135) 4099119..4099718 - 600 WP_011409027.1 type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein Antitoxin
MJJ07_RS19175 (MJJ07_19140) 4100083..4100373 + 291 WP_228329665.1 FaeA/PapI family transcriptional regulator -
MJJ07_RS19180 (MJJ07_19145) 4100405..4100980 + 576 WP_011409029.1 BrxE family protein -
MJJ07_RS19185 (MJJ07_19150) 4100962..4101993 - 1032 WP_042465093.1 IS630 family transposase -
MJJ07_RS19190 (MJJ07_19155) 4102492..4102782 + 291 WP_011409031.1 hypothetical protein -
MJJ07_RS19195 (MJJ07_19160) 4102763..4103230 + 468 WP_181718264.1 hypothetical protein -
MJJ07_RS19205 (MJJ07_19170) 4103500..4104036 + 537 WP_011409032.1 lipocalin family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 4097649..4107096 9447


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Nucleotidyl transferase AbiEii toxin, Type IV TA system

(41-269)

Antitoxin

Transcriptional regulator, AbiEi antitoxin

(7-52)


Sequences

Toxin        


Download         Length: 308 a.a.        Molecular weight: 34114.16 Da        Isoelectric Point: 5.4588

>T236022 WP_011259680.1 NZ_CP092381:c4099122-4098199 [Xanthomonas oryzae]
MNEPDKSRRTVAASVRARLLNKARAERLDFNLLLTRYALERVLYRLSVSEQQGQFLLKGALLFDIWFDIPHRPTHDADLL
GFGSTEIPHLEDLFRRISQIASDDGIVFQADSVKAAEIRKEANYAGVRVTMIGLLDGARCTVQIDIGFGDAVTPGPDNVQ
YPVILDGMPQPQLRVYPRYTVVAEKLEAMVKLGILNSRMKDYFDLWVLAGHSDFDGAVLATAIRATFECRGTAIPPGAPL
GLTDEFGLDEQKTKQWQAFLRKNTLEPMPLTTVIEALREFVLPVLAALAAGEGFDRQWRAGAGWDAA

Download         Length: 924 bp

>T236022 NZ_LR135181:216410-216676 [Enterococcus faecium]
ATGAGTAACTATACAGTCGCAATCAAAAACTCTGCGAAAGTGGATTTAAGAAAAATCAAGCAAACGAATTTAAAGAAACA
ATTTGAAGAAGTGATTCAGACATTGAAGGAAGATCCATATATGCCCACGCAGTCTTTTGAAAAGCTGAGACCTACACATG
AAGGCAGATACTCACGCAGGCTGAATAGACAGCATCGAGTGGTTTACAAAGTTGATGAGGAAAATAAAGTTGTAGAAATT
TATTCTGCCTGGACACATTATGAGTGA

Antitoxin


Download         Length: 200 a.a.        Molecular weight: 22037.74 Da        Isoelectric Point: 10.1240

>AT236022 WP_011409027.1 NZ_CP092381:c4099718-4099119 [Xanthomonas oryzae]
MDTTVDKLLELVRTRGLLRPHDLAPLGIPRVALTRAVRRGQLERVGRGLYGLVARPVSAHGTLAEVARRVPKGVVCLLSA
LRVHDLTTQAPFEVWLAIDNKAAAPKLDYPPLRLVRFSGPALSEGVEEHVVDGVPVHVTSVAKTVADCFKYRNKIGIDVA
LEALREAWVARRMTSDEIWHYAKIDRVANVMRPYLESLA

Download         Length: 600 bp

>AT236022 NZ_LR135181:216147-216410 [Enterococcus faecium]
ATGGCTAATACAACGATGAATCCTAGCACTGCTCGTAAAAATTTTTATCAGTTATTGAAAGAGGTAAATGAAAATCATAC
TGAAATCGAGATTATTAGTGATCGTAGTGGAAACAATGCTGTATTGATTGGGCTGGAAGACTGGAGAGCGATTCAAGAAA
CCCTTTTTCTTGAGCAAACAGGTACTTTAGATAAAGTACGAGACCGCGAAAAAGACGACAGTAGCTTTACGAATATCGAT
GATATTGATTGGGAAGCTCTTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0K0GMB6

Antitoxin

Source ID Structure
AlphaFold DB A0A854CLN1

References