Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relB-parE/ParE-RHH
Location 3592947..3593503 Replicon chromosome
Accession NZ_CP092381
Organism Xanthomonas oryzae strain HN2011

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag MJJ07_RS16995 Protein ID WP_229001948.1
Coordinates 3592947..3593198 (-) Length 84 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A854CIX2
Locus tag MJJ07_RS17000 Protein ID WP_011408759.1
Coordinates 3593225..3593503 (-) Length 93 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MJJ07_RS16945 (MJJ07_16920) 3588717..3589808 + 1092 WP_113195651.1 ribonuclease D -
MJJ07_RS16950 (MJJ07_16925) 3589884..3590221 - 338 Protein_3238 ATP-dependent DNA ligase -
MJJ07_RS16955 (MJJ07_16930) 3590503..3590679 - 177 Protein_3239 DUF3606 domain-containing protein -
MJJ07_RS16960 (MJJ07_16935) 3590901..3591302 + 402 WP_011259345.1 H-NS family nucleoid-associated regulatory protein -
MJJ07_RS16970 3591733..3591861 - 129 WP_012444694.1 hypothetical protein -
MJJ07_RS16975 (MJJ07_16945) 3591830..3591949 - 120 Protein_3242 IS3 family transposase -
MJJ07_RS16980 (MJJ07_16950) 3592166..3592420 - 255 WP_223293127.1 hypothetical protein -
MJJ07_RS16985 3592489..3592623 - 135 WP_011051575.1 hypothetical protein -
MJJ07_RS16990 (MJJ07_16955) 3592616..3592870 - 255 WP_198912806.1 hypothetical protein -
MJJ07_RS16995 (MJJ07_16960) 3592947..3593198 - 252 WP_229001948.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
MJJ07_RS17000 (MJJ07_16965) 3593225..3593503 - 279 WP_011408759.1 CopG family ribbon-helix-helix protein Antitoxin
MJJ07_RS17005 (MJJ07_16970) 3593699..3594043 - 345 WP_199285675.1 hypothetical protein -
MJJ07_RS17010 (MJJ07_16975) 3594949..3596133 - 1185 WP_011408760.1 IS256-like element IS1113 family transposase -
MJJ07_RS17015 (MJJ07_16980) 3596714..3597679 + 966 WP_109181928.1 IS1595-like element ISXo5 family transposase -
MJJ07_RS17020 (MJJ07_16985) 3597829..3598386 + 558 WP_011259349.1 DNA-3-methyladenine glycosylase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-81)

Antitoxin

Ribbon-helix-helix protein, CopG

(5-42)


Sequences

Toxin        


Download         Length: 84 a.a.        Molecular weight: 9603.92 Da        Isoelectric Point: 9.9718

>T236021 WP_229001948.1 NZ_CP092381:c3593198-3592947 [Xanthomonas oryzae]
MLRLREFLRPKNPDAARRAGEAIRRGVQALGAHPRMGRLIEDLSEQYREWLIDFGDSGYVARYRFDGDTVTILAVRHQKE
AGY

Download         Length: 252 bp

>T236021 NZ_LR135180:51959-52822 [Enterococcus faecium]
ATGGCAAATATAGTCAATTTTACTGACAAACAGTTTGAGAATCGCTTAAATGATAATTTAGAAGAATTGGTTCAAGGAAA
AAAAGCGGTTGAATCGCCAACCGCTTTTTTACTTGGTGGGCAACCAGGGTCAGGAAAAACCAGTTTGCGATCAGCAATTT
TTGAAGAAACACAAGGGAATGTTGTTGTCATTGATAATGATACCTTCAAACAACAGCACCCAAATTTTGACGAATTAGTG
AAACTTTATGAAAAAGACGTGGTAAAACACGTTACCCCTTATTCTAATCGTATGACAGAAGCACTTATTAGCCGTTTAAG
CGATCAAGGCTATAATTTAGTGATTGAAGGAACAGGACGAACAACAGACGTTCCTATTCAAACCGCAACAATGCTTCAAG
CCAAAGGTTATGAAACAAAAATATACGTCATGGCAGTACCGAAAATTGAATCATACTTAGGAACGATTGAACGATATGAA
ACCATGTATGCAGATGATCCAATGACAGCCAGGGCAACACCAAAACAAGCACATGATATTGTGGTTAAAAATTTACCTAA
CAATTTAGAAACCCTTCAAAAAACGGGCTTATTTAGCGATATAAGGCTTTACAATAGAGAAGGAGTGAAACTCTATTCAA
GCTTAGAAACGCCTTCCATTAGTCCGAAAGAGACCTTAGAAAGAGAATTAAATCGTAAAGTATCAGGGAAAGAAATTCAA
CCGACTTTGGAGAGAATAGAGCAAAAAATGGTTCAAAATCAACACCAAGAAACCCCTGAATTTAAAGCAATTCAACAAAA
AATGGAAAGCTTGCAGCCACCTACACCACCAATACCCAAAACACCTAAACTTCCAGGACTTTAA

Antitoxin


Download         Length: 93 a.a.        Molecular weight: 10826.11 Da        Isoelectric Point: 4.9736

>AT236021 WP_011408759.1 NZ_CP092381:c3593503-3593225 [Xanthomonas oryzae]
MVTATSIKLDDELKGRVQHLAESRRRTPHWIMREAIEQYVEREEKREALNRDTLKAWDEFQATGLHVTAEEVDKWLASWG
TDDELPPPECHK

Download         Length: 279 bp

>AT236021 NZ_LR135180:51685-51957 [Enterococcus faecium]
ATGGCAGTTACGTATGAAAAAACTTTTGAAATAGAGATCATTAACGAATTATCGGCAAGCGTTTATAATCGAGTATTAAA
CTATGTTTTGAATCATGAATTAAATAAAAATGACTCTCAATTATTGGAAGTCAATTTATTAAAACAATTAAAGCTTGCAA
AACGTGTAAATCTTTTTGATTATTCTTTAGAAGAATTAAAAGCCGTTCATGAGTATTGGCGGTCAATGAATCGTTACTCA
AAACAAGTTTTGAATAAAGAGAAAGTGGCTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A854CIX2

References