236020

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pmenTA/darT(toxin)
Location 1811932..1812677 Replicon chromosome
Accession NZ_CP092381
Organism Xanthomonas oryzae strain HN2011

Toxin (Protein)


Gene name pmenT Uniprot ID -
Locus tag MJJ07_RS08640 Protein ID WP_199285672.1
Coordinates 1812348..1812677 (-) Length 110 a.a.

Antitoxin (Protein)


Gene name pmenA Uniprot ID -
Locus tag MJJ07_RS08635 Protein ID WP_011407754.1
Coordinates 1811932..1812351 (-) Length 140 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MJJ07_RS08615 (MJJ07_08605) 1808221..1808547 - 327 Protein_1641 hypothetical protein -
MJJ07_RS08620 (MJJ07_08610) 1808849..1810084 + 1236 WP_011257570.1 ISL3-like element ISXoo13 family transposase -
MJJ07_RS08625 (MJJ07_08615) 1810122..1810778 - 657 WP_075246166.1 phosphate phosphatase -
MJJ07_RS08635 (MJJ07_08625) 1811932..1812351 - 420 WP_011407754.1 macro domain-containing protein Antitoxin
MJJ07_RS08640 (MJJ07_08630) 1812348..1812677 - 330 WP_199285672.1 DUF4433 domain-containing protein Toxin
MJJ07_RS08645 (MJJ07_08635) 1812780..1814099 + 1320 WP_109182117.1 IS701-like element ISXo15 family transposase -
MJJ07_RS08650 (MJJ07_08640) 1814143..1814478 - 336 WP_011407757.1 DarT ssDNA thymidine ADP-ribosyltransferase family protein -
MJJ07_RS08655 (MJJ07_08645) 1814810..1815736 - 927 WP_011257932.1 Grx4 family monothiol glutaredoxin -
MJJ07_RS08660 (MJJ07_08650) 1815782..1816573 + 792 WP_011407758.1 polysaccharide deacetylase family protein -
MJJ07_RS08670 (MJJ07_08660) 1816875..1817546 - 672 WP_011407759.1 class I SAM-dependent methyltransferase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside IScluster/Tn - - 1808849..1814099 5250


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

ssDNA thymidine ADP-ribosyltransferase, DarT

(3-108)

Antitoxin

Macro domain

(18-130)


Sequences

Toxin        


Download         Length: 110 a.a.        Molecular weight: 13145.86 Da        Isoelectric Point: 7.1160

>T236020 WP_199285672.1 NZ_CP092381:c1812677-1812348 [Xanthomonas oryzae]
MHHVAERRWPFLFTDSHAYCQLASFYSDLSDLDKIDWPLLQARDFRRDPDDPAKFERYQAEALIHRHLPLDGLRGIVCHT
DGLKQTIERQLQERNLKLPVHTRTDWYFR

Download         Length: 330 bp

>T236020 NZ_LR135179:473466-473807 [Enterococcus faecium]
GTGTCAGGAGAAAGAATTTATATTCCTAAAAAAGGTGATATTGTATGGATTTATTTTGATCCCTCATTAGGAAAAGAAAT
TCAAAAAAGACGACCAGGACTAGTCGTCTCTCGTTATGAATTTAACCGTAAAACAATGTTTTCGGTCATATGTCCAATTA
CTTCCACTATAAAGAATTTACCGACACGTTACTCATTACCTGAAGAGCTAGATATAAAAGGACAAGTAATTATTTCACAA
TTAAAATCTCTTGATTTTAAGGAACGAAAACTCAAAAAAATAGAAAACTTACCATTGCAAGACATGGCTAAAATTGATCA
GATTATACAGTATATGTTTTAA

Antitoxin


Download         Length: 140 a.a.        Molecular weight: 15607.02 Da        Isoelectric Point: 6.4733

>AT236020 WP_011407754.1 NZ_CP092381:c1812351-1811932 [Xanthomonas oryzae]
MITFTQGNLLESGAEALVNTVNTVGVMGKGIALMFKERFKENFLRYAAACKDNQVRIGKIFVTEVNELDGPRWIINFPTK
QHWRGDSRIEWITEGLQDLHRFLIENKVKSIAIPPLGAGNGGLDWAEVRPLIEEVLGNL

Download         Length: 420 bp

>AT236020 NZ_LR135179:473236-473466 [Enterococcus faecium]
ATGCTTGTTACAAAATCTAGATTACAAGGAAGTTCTGTAGTGGTAACTTTACCTTCTGATAACGGAAAGAAACCTTCAGA
AAACCAAGAATATATCGTTGTGTATTCTGACGATGGTACAATTACGTTAGTTCCAAAAATTGAAGATCCATTTAGTGGTG
GGGAAGAGGCCGAGTATTATGAGAAAGACGAATGGGAAGATTTAACTCCTGAAGGGAGAGAAATTTTATAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References