236019

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 1154680..1155030 Replicon chromosome
Accession NZ_CP092381
Organism Xanthomonas oryzae strain HN2011

Toxin (Protein)


Gene name EcnB Uniprot ID G7TLC7
Locus tag MJJ07_RS05410 Protein ID WP_011257368.1
Coordinates 1154896..1155030 (+) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID G7TLC8
Locus tag MJJ07_RS05405 Protein ID WP_011407410.1
Coordinates 1154680..1154832 (+) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MJJ07_RS05380 (MJJ07_05365) 1150960..1151643 - 684 WP_011257363.1 dTMP kinase -
MJJ07_RS05385 (MJJ07_05370) 1152123..1152665 - 543 Protein_1033 GTPase -
MJJ07_RS05390 (MJJ07_05375) 1152662..1153117 - 456 Protein_1034 hypothetical protein -
MJJ07_RS05395 (MJJ07_05380) 1153109..1153327 - 219 Protein_1035 hypothetical protein -
MJJ07_RS05400 (MJJ07_05385) 1153649..1154572 + 924 WP_011407409.1 arginase -
MJJ07_RS05405 (MJJ07_05390) 1154680..1154832 + 153 WP_011407410.1 entericidin A/B family lipoprotein Antitoxin
MJJ07_RS05410 (MJJ07_05395) 1154896..1155030 + 135 WP_011257368.1 entericidin A/B family lipoprotein Toxin
MJJ07_RS05415 (MJJ07_05400) 1155271..1155480 + 210 WP_011407411.1 CsbD family protein -
MJJ07_RS05420 (MJJ07_05405) 1155649..1156938 + 1290 WP_069959696.1 tryptophan--tRNA ligase -
MJJ07_RS05425 (MJJ07_05410) 1157069..1158013 + 945 WP_113195610.1 MBL fold metallo-hydrolase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4457.33 Da        Isoelectric Point: 10.2040

>T236019 WP_011257368.1 NZ_CP092381:1154896-1155030 [Xanthomonas oryzae]
MKRAIVLLVLSMLSVGLLSGCNTVAGAGKDVKGAGEKVEDAARK

Download         Length: 135 bp

>T236019 NZ_LR135179:174759-175025 [Enterococcus faecium]
ATGAGTAACTATACAGTCGCAATCAAAAACTCTGCGAAAGTGGATTTAAGAAAAATCAAGCAATCGAATTTAAAGAAACA
ATTTGAAGAAGTGATTCAGACATTGAAGGAAGATCCATATATGCCCACGCAGTCTTTTGAAAAGCTGAGACCTACACATG
AAGGCAGATACTCACGCAGGCTGAATAGACAGCATCGAGTGGTTTACAAAGTTGATGAGGAAAATAAAGTTGTGGAAATT
TATTCTGCCTGGACACATTATGAGTGA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5046.99 Da        Isoelectric Point: 8.7942

>AT236019 WP_011407410.1 NZ_CP092381:1154680-1154832 [Xanthomonas oryzae]
MKRLLTLMVLGLFSAGVMTGCNTVAGAGKDLQGAGGKVEKTAEKCSDGKC

Download         Length: 153 bp

>AT236019 NZ_LR135179:174496-174759 [Enterococcus faecium]
ATGGCTAATACAACGATGAATCCTAGCACAGCTCGTAAAAATTTTTATCAGTTATTGAAAGAGGTAAATGAAAATCATAC
TGAAATCGAGATTATTAGTGATCGTAGTGGAAACAATGCTGTATTGATTGGGCTAGAAGACTGGAGAGCGATTCAAGAAA
CCCTTTTTCTTGAGCAAACAGGTACTTTAGATAAAGTACGAGACCGCGAAAAAGACGACAGTGGCTTTACGAATATCGAT
GATATTGATTGGGAAGCTCTTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0C5UG40

Antitoxin

Source ID Structure
AlphaFold DB A0A0C5V759

References