Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) rlegTA/AbiEii-AbiEi
Location 3144441..3145960 Replicon chromosome
Accession NZ_CP092380
Organism Xanthomonas oryzae strain GD1358

Toxin (Protein)


Gene name rlegT Uniprot ID A0A0K0GMB6
Locus tag MJJ09_RS14575 Protein ID WP_011259680.1
Coordinates 3144441..3145364 (-) Length 308 a.a.

Antitoxin (Protein)


Gene name rlegA Uniprot ID A0A854CLN1
Locus tag MJJ09_RS14580 Protein ID WP_011409027.1
Coordinates 3145361..3145960 (-) Length 200 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MJJ09_RS14550 (MJJ09_14520) 3140634..3141166 + 533 Protein_2776 methyltransferase domain-containing protein -
MJJ09_RS14555 (MJJ09_14525) 3141183..3141671 - 489 WP_069959937.1 hypothetical protein -
MJJ09_RS14560 (MJJ09_14530) 3141766..3142731 + 966 Protein_2778 IS1595-like element ISXo5 family transposase -
MJJ09_RS14565 (MJJ09_14535) 3143183..3143425 - 243 WP_011409025.1 hypothetical protein -
MJJ09_RS14570 (MJJ09_14540) 3143891..3144361 + 471 WP_228329666.1 helix-turn-helix domain-containing protein -
MJJ09_RS14575 (MJJ09_14545) 3144441..3145364 - 924 WP_011259680.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein Toxin
MJJ09_RS14580 (MJJ09_14550) 3145361..3145960 - 600 WP_011409027.1 type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein Antitoxin
MJJ09_RS14585 (MJJ09_14555) 3146325..3146615 + 291 WP_228329665.1 FaeA/PapI family transcriptional regulator -
MJJ09_RS14590 (MJJ09_14560) 3146647..3147222 + 576 WP_011409029.1 BrxE family protein -
MJJ09_RS14595 (MJJ09_14565) 3147204..3148235 - 1032 WP_042465093.1 IS630 family transposase -
MJJ09_RS14600 (MJJ09_14570) 3148734..3149024 + 291 WP_011409031.1 hypothetical protein -
MJJ09_RS14605 (MJJ09_14575) 3149005..3149472 + 468 WP_181718264.1 hypothetical protein -
MJJ09_RS14615 (MJJ09_14585) 3149742..3150278 + 537 WP_011409032.1 lipocalin family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Nucleotidyl transferase AbiEii toxin, Type IV TA system

(41-269)

Antitoxin

Transcriptional regulator, AbiEi antitoxin

(7-52)


Sequences

Toxin        


Download         Length: 308 a.a.        Molecular weight: 34114.16 Da        Isoelectric Point: 5.4588

>T236016 WP_011259680.1 NZ_CP092380:c3145364-3144441 [Xanthomonas oryzae]
MNEPDKSRRTVAASVRARLLNKARAERLDFNLLLTRYALERVLYRLSVSEQQGQFLLKGALLFDIWFDIPHRPTHDADLL
GFGSTEIPHLEDLFRRISQIASDDGIVFQADSVKAAEIRKEANYAGVRVTMIGLLDGARCTVQIDIGFGDAVTPGPDNVQ
YPVILDGMPQPQLRVYPRYTVVAEKLEAMVKLGILNSRMKDYFDLWVLAGHSDFDGAVLATAIRATFECRGTAIPPGAPL
GLTDEFGLDEQKTKQWQAFLRKNTLEPMPLTTVIEALREFVLPVLAALAAGEGFDRQWRAGAGWDAA

Download         Length: 924 bp

>T236016 NZ_LR135174:536749-537090 [Enterococcus faecium]
GTGTCAGAAGAAAGAATTTATATTCCTAAAAAAGGTGATATTGTATGGATTGATTTTGATCCCTCCGTAGGAAAAGAAAT
TCAAAAAAGACGACCAGGACTAGTCGTCTCTCGTTATGAATTTAACCGTAAAACAATGTTTTCGGTCATATGTCCAATTA
CTTCCACTATAAAGAATTTACCGACACGTTACTCATTACCTGAAGAGCTAGATATAAAAGGACAAGTAATTATTACACAA
TTAAAATCTCTTGATTTTAAGGAACGAAAACTCAAAAAAATAGAAAACTTACCATTGCAAGACATGGCTAAAATTGATCA
GATTATACAGTATATGTTTTAA

Antitoxin


Download         Length: 200 a.a.        Molecular weight: 22037.74 Da        Isoelectric Point: 10.1240

>AT236016 WP_011409027.1 NZ_CP092380:c3145960-3145361 [Xanthomonas oryzae]
MDTTVDKLLELVRTRGLLRPHDLAPLGIPRVALTRAVRRGQLERVGRGLYGLVARPVSAHGTLAEVARRVPKGVVCLLSA
LRVHDLTTQAPFEVWLAIDNKAAAPKLDYPPLRLVRFSGPALSEGVEEHVVDGVPVHVTSVAKTVADCFKYRNKIGIDVA
LEALREAWVARRMTSDEIWHYAKIDRVANVMRPYLESLA

Download         Length: 600 bp

>AT236016 NZ_LR135174:536519-536749 [Enterococcus faecium]
ATGCTTGTTACAAAATCTAGATTACAAGGAAGTTCTGTAGTGGTAACTTTACCTTCTGATAACGGAAAGAAACCTTCAGA
AAACCAAGAATATATCGTTGTGTATTCTGATGATGGAACAATTACGTTAGTTCCAAAAATTGAAGATCCATTTAGTGGTG
GGGAAGAGGCCGAGTATTATGAGAAAGACGAATGGGAAGATTTAACTCCTGAAGGGAGAGAAATTTTATAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0K0GMB6

Antitoxin

Source ID Structure
AlphaFold DB A0A854CLN1

References