Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pmenTA/darT(toxin)
Location 884651..885396 Replicon chromosome
Accession NZ_CP092380
Organism Xanthomonas oryzae strain GD1358

Toxin (Protein)


Gene name pmenT Uniprot ID -
Locus tag MJJ09_RS04280 Protein ID WP_199285672.1
Coordinates 885067..885396 (-) Length 110 a.a.

Antitoxin (Protein)


Gene name pmenA Uniprot ID -
Locus tag MJJ09_RS04275 Protein ID WP_011407754.1
Coordinates 884651..885070 (-) Length 140 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MJJ09_RS04255 (MJJ09_04250) 880943..881269 - 327 Protein_800 hypothetical protein -
MJJ09_RS04260 (MJJ09_04255) 881571..882805 + 1235 Protein_801 ISL3 family transposase -
MJJ09_RS04265 (MJJ09_04260) 882843..883481 - 639 WP_011407753.1 phosphate phosphatase -
MJJ09_RS04270 (MJJ09_04265) 883634..884599 - 966 Protein_803 IS5-like element ISXo1 family transposase -
MJJ09_RS04275 (MJJ09_04270) 884651..885070 - 420 WP_011407754.1 macro domain-containing protein Antitoxin
MJJ09_RS04280 (MJJ09_04275) 885067..885396 - 330 WP_199285672.1 DUF4433 domain-containing protein Toxin
MJJ09_RS04285 (MJJ09_04280) 885499..886816 + 1318 Protein_806 IS701-like element ISXo15 family transposase -
MJJ09_RS04290 (MJJ09_04285) 886860..887195 - 336 WP_011407757.1 DarT ssDNA thymidine ADP-ribosyltransferase family protein -
MJJ09_RS04295 (MJJ09_04290) 887527..888453 - 927 WP_011257932.1 Grx4 family monothiol glutaredoxin -
MJJ09_RS04300 (MJJ09_04295) 888499..889290 + 792 WP_011407758.1 polysaccharide deacetylase family protein -
MJJ09_RS04310 (MJJ09_04305) 889592..890263 - 672 WP_011407759.1 class I SAM-dependent methyltransferase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside IScluster/Tn - - 881571..886816 5245


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

ssDNA thymidine ADP-ribosyltransferase, DarT

(3-108)

Antitoxin

Macro domain

(18-130)


Sequences

Toxin        


Download         Length: 110 a.a.        Molecular weight: 13145.86 Da        Isoelectric Point: 7.1160

>T236014 WP_199285672.1 NZ_CP092380:c885396-885067 [Xanthomonas oryzae]
MHHVAERRWPFLFTDSHAYCQLASFYSDLSDLDKIDWPLLQARDFRRDPDDPAKFERYQAEALIHRHLPLDGLRGIVCHT
DGLKQTIERQLQERNLKLPVHTRTDWYFR

Download         Length: 330 bp

>T236014 NZ_LR135170:430167-430508 [Enterococcus faecium]
GTGTCAGAAGAAAGAATTTATATTCCTAAAAAAGGTGATATTGTATGGATTGATTTTGATCCCTCCGTAGGAAAAGAAAT
TCAAAAAAGACGACCAGGACTAGTCGTCTCTCGTTATGAATTTAACCGTAAAACAATGTTTTCGGTCATATGTCCAATTA
CTTCCACTATAAAGAATTTACCGACACGTTACTCATTACCTGAAGAGCTAGATATAAAAGGACAAGTAATTATTTCACAA
TTAAAATCTCTTGATTTTAAGGAACGAAAACTCAAAAAAATAGAAAACTTACCATTGCAAGACATGGCTAAAATTGATCA
GATTATACAGTATATGTTTTAA

Antitoxin


Download         Length: 140 a.a.        Molecular weight: 15607.02 Da        Isoelectric Point: 6.4733

>AT236014 WP_011407754.1 NZ_CP092380:c885070-884651 [Xanthomonas oryzae]
MITFTQGNLLESGAEALVNTVNTVGVMGKGIALMFKERFKENFLRYAAACKDNQVRIGKIFVTEVNELDGPRWIINFPTK
QHWRGDSRIEWITEGLQDLHRFLIENKVKSIAIPPLGAGNGGLDWAEVRPLIEEVLGNL

Download         Length: 420 bp

>AT236014 NZ_LR135170:429937-430167 [Enterococcus faecium]
ATGCTTGTTACAAAATCTAGATTACAAGGAAGTTCTGTAGTGGTAACTTTACCTTCTGATAACGGAAAGAAACCTTCAGA
AAACCAAGAATATATCGTTGTGTATTCTGATGATGGAACAATTACGTTAGTTCCAAAAATTGAAGATCCATTTAGTGGTG
GGGAAGAGGCCGAGTATTATGAGAAAGACGAATGGGAAGATTTAACTCCTGAAGGGAGAGAAATTTTATAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References