236013

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 225872..226222 Replicon chromosome
Accession NZ_CP092380
Organism Xanthomonas oryzae strain GD1358

Toxin (Protein)


Gene name EcnB Uniprot ID G7TLC7
Locus tag MJJ09_RS01065 Protein ID WP_011257368.1
Coordinates 226088..226222 (+) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID G7TLC8
Locus tag MJJ09_RS01060 Protein ID WP_011407410.1
Coordinates 225872..226024 (+) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MJJ09_RS01035 (MJJ09_01030) 222143..222826 - 684 WP_011257363.1 dTMP kinase -
MJJ09_RS01040 (MJJ09_01035) 223306..223848 - 543 Protein_195 GTPase -
MJJ09_RS01045 (MJJ09_01040) 223845..224309 - 465 Protein_196 hypothetical protein -
MJJ09_RS01050 (MJJ09_01045) 224301..224519 - 219 Protein_197 hypothetical protein -
MJJ09_RS01055 (MJJ09_01050) 224841..225764 + 924 WP_011407409.1 arginase -
MJJ09_RS01060 (MJJ09_01055) 225872..226024 + 153 WP_011407410.1 entericidin A/B family lipoprotein Antitoxin
MJJ09_RS01065 (MJJ09_01060) 226088..226222 + 135 WP_011257368.1 entericidin A/B family lipoprotein Toxin
MJJ09_RS01070 (MJJ09_01065) 226466..226675 + 210 WP_011407411.1 CsbD family protein -
MJJ09_RS01075 (MJJ09_01070) 226844..228133 + 1290 WP_069959696.1 tryptophan--tRNA ligase -
MJJ09_RS01080 (MJJ09_01075) 228264..229208 + 945 WP_027704118.1 MBL fold metallo-hydrolase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4457.33 Da        Isoelectric Point: 10.2040

>T236013 WP_011257368.1 NZ_CP092380:226088-226222 [Xanthomonas oryzae]
MKRAIVLLVLSMLSVGLLSGCNTVAGAGKDVKGAGEKVEDAARK

Download         Length: 135 bp

>T236013 NZ_LR135170:190854-191120 [Enterococcus faecium]
ATGAGTAACTATACAGTCGCAATCAAAAACTCTGCGAAAGTGGATTTAAGAAAAATCAAGCAATCGAATTTAAAGAAACA
ATTTGAAGAAGTGATTCAGACATTGAAGGAAGATCCATATATGCCCACGCAGTCTTTTGAAAAGCTGAGACCTACACATG
AAGGCAGATACTCACGCAGGCTGAATAGACAGCACCGAGTGGTTTACAAAGTTGATGAGGAAAATAAAGTTGTGGAAATT
TATTCTGCCTGGACACATTATGAGTGA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5046.99 Da        Isoelectric Point: 8.7942

>AT236013 WP_011407410.1 NZ_CP092380:225872-226024 [Xanthomonas oryzae]
MKRLLTLMVLGLFSAGVMTGCNTVAGAGKDLQGAGGKVEKTAEKCSDGKC

Download         Length: 153 bp

>AT236013 NZ_LR135170:190591-190854 [Enterococcus faecium]
ATGGCTAATACAACGATGAATCCTAGCACAGCTCGTAAAAATTTTTATCAGTTATTGAAAGAGGTAAATGAAAATCATAC
TGAAATCGAGATTATTAGTGATCGTAGTGGAAACAATGCTGTATTGATTGGGCTAGAAGACTGGAGAGCGATTCAAGAAA
CCCTTTTTCTTGAGCAAACAGGTACTTTAGATAAAGTACGAGACCGCGAAAAAGACGACAGTGGCTTTACGAATATCGAT
AATATTGATTGGGAAGCTCTTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0C5UG40

Antitoxin

Source ID Structure
AlphaFold DB A0A0C5V759

References