236011

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 3670578..3670928 Replicon chromosome
Accession NZ_CP092379
Organism Xanthomonas oryzae strain GIV

Toxin (Protein)


Gene name EcnB Uniprot ID G7TLC7
Locus tag MJJ06_RS17465 Protein ID WP_011257368.1
Coordinates 3670578..3670712 (-) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID G7TLC8
Locus tag MJJ06_RS17470 Protein ID WP_011407410.1
Coordinates 3670776..3670928 (-) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MJJ06_RS17450 (MJJ06_17435) 3667595..3668539 - 945 WP_027704118.1 MBL fold metallo-hydrolase -
MJJ06_RS17455 (MJJ06_17440) 3668670..3669959 - 1290 WP_069959696.1 tryptophan--tRNA ligase -
MJJ06_RS17460 (MJJ06_17445) 3670128..3670337 - 210 WP_011407411.1 CsbD family protein -
MJJ06_RS17465 (MJJ06_17450) 3670578..3670712 - 135 WP_011257368.1 entericidin A/B family lipoprotein Toxin
MJJ06_RS17470 (MJJ06_17455) 3670776..3670928 - 153 WP_011407410.1 entericidin A/B family lipoprotein Antitoxin
MJJ06_RS17475 (MJJ06_17460) 3671036..3671959 - 924 WP_011407409.1 arginase -
MJJ06_RS17480 (MJJ06_17465) 3672281..3672499 + 219 Protein_3338 hypothetical protein -
MJJ06_RS17485 (MJJ06_17470) 3672491..3672946 + 456 Protein_3339 hypothetical protein -
MJJ06_RS17490 (MJJ06_17475) 3672943..3673485 + 543 Protein_3340 GTPase -
MJJ06_RS17495 (MJJ06_17480) 3673965..3674648 + 684 WP_011257363.1 dTMP kinase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4457.33 Da        Isoelectric Point: 10.2040

>T236011 WP_011257368.1 NZ_CP092379:c3670712-3670578 [Xanthomonas oryzae]
MKRAIVLLVLSMLSVGLLSGCNTVAGAGKDVKGAGEKVEDAARK

Download         Length: 135 bp

>T236011 NZ_LR135169:173814-174080 [Enterococcus faecium]
ATGAGTAACTATACAGTCGCAATCAAAAACTCTGCGAAAGTGGATTTAAGAAAAATCAAGCAATCGAATTTAAAGAAACA
ATTTGAAGAAGTGATTCAGACATTGAAGGAAGATCCATATATGCCCACGCAGTCTTTTGAAAAGCTGAGACCTACACATG
AAGGCAGATACTCACGCAGGCTGAATAGACAGCATCGAGTGGTTTACAAAGTTGATGAGGAAAATAAAGTTGTGGAAATT
TATTCTGCCTGGACACATTATGAGTGA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5046.99 Da        Isoelectric Point: 8.7942

>AT236011 WP_011407410.1 NZ_CP092379:c3670928-3670776 [Xanthomonas oryzae]
MKRLLTLMVLGLFSAGVMTGCNTVAGAGKDLQGAGGKVEKTAEKCSDGKC

Download         Length: 153 bp

>AT236011 NZ_LR135169:173551-173814 [Enterococcus faecium]
ATGGCTAATACAACGATGAATCCTAGCACAGCTCGTAAAAATTTTTATCAGTTATTGAAAGAGGTAAATGAAAATCATAC
TGAAATCGAGATTATTAGTGATCGTAGTGGAAACAATGCTGTATTGATTGGGCTAGAAGACTGGAGAGCGATTCAAGAAA
CCCTTTTTCTTGAGCAAACAGGTACTTTAGATAAAGTACGAGACCGCGAAAAAGACGACAGTGGCTTTACGAATATCGAT
GATATTGATTGGGAAGCTCTTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0C5UG40

Antitoxin

Source ID Structure
AlphaFold DB A0A0C5V759

References