Detailed information of TA system TA236009

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relB-parE/ParE-RHH
• Location: 1205891..1206447
• Replicon: chromosome
• Accession: NZ_CP092379
• Organism: Xanthomonas oryzae strain GIV

Toxin (Protein)

• Gene name: parE
• Uniprot ID: -
• Locus tag: MJJ06_RS05730
• Protein ID: WP_229001948.1
• Coordinates: 1206196..1206447 (+)
• Length: 84 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: A0A854CIX2
• Locus tag: MJJ06_RS05725
• Protein ID: WP_011408759.1
• Coordinates: 1205891..1206169 (+)
• Length: 93 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
MJJ06_RS05705 (MJJ06_05710)	1201009..1201566	-	558	WP_011259349.1	DNA-3-methyladenine glycosylase	-
MJJ06_RS05710 (MJJ06_05715)	1201716..1202681	-	966	WP_109181928.1	IS1595-like element ISXo5 family transposase	-
MJJ06_RS05715 (MJJ06_05720)	1203337..1204445	+	1109	Protein_1094	IS256 family transposase	-
MJJ06_RS05720 (MJJ06_05725)	1205351..1205695	+	345	WP_199285675.1	hypothetical protein	-
MJJ06_RS05725 (MJJ06_05730)	1205891..1206169	+	279	WP_011408759.1	CopG family ribbon-helix-helix protein	Antitoxin
MJJ06_RS05730 (MJJ06_05735)	1206196..1206447	+	252	WP_229001948.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
MJJ06_RS05735 (MJJ06_05740)	1206708..1206905	+	198	WP_153296741.1	hypothetical protein	-
MJJ06_RS05740 (MJJ06_05745)	1206974..1207228	+	255	WP_223293127.1	hypothetical protein	-
MJJ06_RS05745 (MJJ06_05750)	1207445..1207564	+	120	Protein_1100	IS3 family transposase	-
MJJ06_RS05750	1207533..1207661	+	129	WP_012444694.1	hypothetical protein	-
MJJ06_RS05760 (MJJ06_05760)	1208092..1208493	-	402	WP_011259345.1	H-NS family nucleoid-associated regulatory protein	-
MJJ06_RS05765 (MJJ06_05765)	1208715..1208891	+	177	Protein_1103	DUF3606 domain-containing protein	-
MJJ06_RS05770 (MJJ06_05770)	1209173..1209510	+	338	Protein_1104	ATP-dependent DNA ligase	-
MJJ06_RS05775 (MJJ06_05775)	1209586..1210677	-	1092	WP_041182166.1	ribonuclease D	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (3-81)

Antitoxin

• Ribbon-helix-helix protein, CopG (5-42)

Sequences

Toxin

Protein

• Length: 84 a.a.
• Molecular weight: 9603.92 Da
• Isoelectric Point: 9.9718

>T236009 WP_229001948.1 NZ_CP092379:1206196-1206447 [Xanthomonas oryzae]
MLRLREFLRPKNPDAARRAGEAIRRGVQALGAHPRMGRLIEDLSEQYREWLIDFGDSGYVARYRFDGDTVTILAVRHQKE
AGY

Nucleotide

• Length: 252 bp

>T236009 NZ_LR134538:1874090-1874353 [Corynebacterium diphtheriae]
GTGGCTTGGGAGATTAGTTTTTCTCCTCGGGCGGTGAAGTCGTTTAAGAAGCTCGATACGGGTGAGCAGCGGAGGGTGAG
TAAGTTTCTGCGGGAGGTTGGCGCCCTTGAGGACCCGAGGTTACGAGGTAAGGCATTAACAGCCAATAAGTCGGGTTTGT
GGCGCTGGCGTGTGGGGGACTATCGGATTATTGCTGACATTGTGGACGCGCATGTTGTCGTCGTTGTGGTTGACGTTGGG
CACCGCTCGAAGGTCTACGACTAA

Antitoxin

Protein

• Length: 93 a.a.
• Molecular weight: 10826.11 Da
• Isoelectric Point: 4.9736

>AT236009 WP_011408759.1 NZ_CP092379:1205891-1206169 [Xanthomonas oryzae]
MVTATSIKLDDELKGRVQHLAESRRRTPHWIMREAIEQYVEREEKREALNRDTLKAWDEFQATGLHVTAEEVDKWLASWG
TDDELPPPECHK

Nucleotide

• Length: 279 bp

>AT236009 NZ_LR134538:1873870-1874106 [Corynebacterium diphtheriae]
ATGAGTGGTTCGGTGATTAGCTTGCGTATCGATGACGAGCAGAAGCGGCGTTTGGATGAGCTGTCGCGACGTACGGGGCG
GCCGTGTTCGTTTTATCTTCGGGAAGCGTTGAGTGCACATCTGGCTGATCTGGAGTATGTGTATCGCTTGGAGGAGGAGG
CTGCTCAGGTTCGTCGTGGGGAGTTGGGAACTGTGCCGTTGAGTCAGCTGGAGCGCGAGTGTGGCTTGGGAGATTAG

Structures

Antitoxin

• AlphaFold DB: A0A854CIX2