Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) rlegTA/AbiEii-AbiEi
Location 700903..702422 Replicon chromosome
Accession NZ_CP092379
Organism Xanthomonas oryzae strain GIV

Toxin (Protein)


Gene name rlegT Uniprot ID A0A0K0GMB6
Locus tag MJJ06_RS03575 Protein ID WP_011259680.1
Coordinates 701499..702422 (+) Length 308 a.a.

Antitoxin (Protein)


Gene name rlegA Uniprot ID A0A854CLN1
Locus tag MJJ06_RS03570 Protein ID WP_011409027.1
Coordinates 700903..701502 (+) Length 200 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MJJ06_RS03535 (MJJ06_03535) 696585..697121 - 537 WP_011409032.1 lipocalin family protein -
MJJ06_RS03545 (MJJ06_03545) 697391..697858 - 468 WP_181718264.1 hypothetical protein -
MJJ06_RS03550 (MJJ06_03550) 697839..698129 - 291 WP_011409031.1 hypothetical protein -
MJJ06_RS03555 (MJJ06_03555) 698628..699659 + 1032 WP_042465093.1 IS630 family transposase -
MJJ06_RS03560 (MJJ06_03560) 699641..700216 - 576 WP_011409029.1 BrxE family protein -
MJJ06_RS03565 (MJJ06_03565) 700248..700568 - 321 WP_011409028.1 FaeA/PapI family transcriptional regulator -
MJJ06_RS03570 (MJJ06_03570) 700903..701502 + 600 WP_011409027.1 type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein Antitoxin
MJJ06_RS03575 (MJJ06_03575) 701499..702422 + 924 WP_011259680.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein Toxin
MJJ06_RS03580 (MJJ06_03580) 702502..702972 - 471 WP_228329666.1 helix-turn-helix domain-containing protein -
MJJ06_RS03585 (MJJ06_03585) 703438..703680 + 243 WP_011409025.1 hypothetical protein -
MJJ06_RS03590 (MJJ06_03590) 704132..705097 - 966 Protein_681 IS1595-like element ISXo5 family transposase -
MJJ06_RS03595 (MJJ06_03595) 705192..705680 + 489 WP_011409022.1 hypothetical protein -
MJJ06_RS03600 (MJJ06_03600) 705697..706229 - 533 Protein_683 methyltransferase domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Nucleotidyl transferase AbiEii toxin, Type IV TA system

(41-269)

Antitoxin

Transcriptional regulator, AbiEi antitoxin

(7-52)


Sequences

Toxin        


Download         Length: 308 a.a.        Molecular weight: 34114.16 Da        Isoelectric Point: 5.4588

>T236008 WP_011259680.1 NZ_CP092379:701499-702422 [Xanthomonas oryzae]
MNEPDKSRRTVAASVRARLLNKARAERLDFNLLLTRYALERVLYRLSVSEQQGQFLLKGALLFDIWFDIPHRPTHDADLL
GFGSTEIPHLEDLFRRISQIASDDGIVFQADSVKAAEIRKEANYAGVRVTMIGLLDGARCTVQIDIGFGDAVTPGPDNVQ
YPVILDGMPQPQLRVYPRYTVVAEKLEAMVKLGILNSRMKDYFDLWVLAGHSDFDGAVLATAIRATFECRGTAIPPGAPL
GLTDEFGLDEQKTKQWQAFLRKNTLEPMPLTTVIEALREFVLPVLAALAAGEGFDRQWRAGAGWDAA

Download         Length: 924 bp

>T236008 NZ_LR134538:c1539836-1539567 [Corynebacterium diphtheriae]
GTGACCTCTTGGGCGATTGAGTTTTCTCCGCGTGCTGCTAAAGAGCTCCGGAAGCTTGGCCGGCCAGTTCAAAAGCACAT
TGTTGCGTATCTTCGAGAAATTTCTACTCTGCCCAATCCGCAAATGCGTGGTAAGGCGTTAACTGGCAACTGGGCAGGTT
TTTGGCGTTGGCGTGTGGGGGATTACCGCCTCGTTGCAGCTATTGAAGATGATCGTGTTGTCGTCGTCGTTGTTTCCATT
GGTCACCGATCTCAGGTTTACGAGGACTAA

Antitoxin


Download         Length: 200 a.a.        Molecular weight: 22037.74 Da        Isoelectric Point: 10.1240

>AT236008 WP_011409027.1 NZ_CP092379:700903-701502 [Xanthomonas oryzae]
MDTTVDKLLELVRTRGLLRPHDLAPLGIPRVALTRAVRRGQLERVGRGLYGLVARPVSAHGTLAEVARRVPKGVVCLLSA
LRVHDLTTQAPFEVWLAIDNKAAAPKLDYPPLRLVRFSGPALSEGVEEHVVDGVPVHVTSVAKTVADCFKYRNKIGIDVA
LEALREAWVARRMTSDEIWHYAKIDRVANVMRPYLESLA

Download         Length: 600 bp

>AT236008 NZ_LR134538:c1540050-1539817 [Corynebacterium diphtheriae]
ATGAGCAATCCTGTTATTAGCCTACGTATCGGGGCGAGTGAAAAAGAGCGGCTTGATGAGCTATCACGGCGTACCGGCCG
GTCAGGATCTTTTTACATACGAGAAGCCTTAGAAAAACATCTTGACGAGCTTGAGTACGTCTATGGCGTTCGCAGCGAGT
ACGAAGCTATCCGACGCGGAGAGCTAGAGACAATCAGCTTGGACGAGGTAGAGCGTGACCTCTTGGGCGATTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0K0GMB6

Antitoxin

Source ID Structure
AlphaFold DB A0A854CLN1

References