Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) KacT-ataR/DUF1778(antitoxin)
Location 152348..153153 Replicon chromosome
Accession NZ_CP092373
Organism Pantoea sp. Z09

Toxin (Protein)


Gene name KacT Uniprot ID -
Locus tag MC269_RS00685 Protein ID WP_239953386.1
Coordinates 152348..152875 (-) Length 176 a.a.

Antitoxin (Protein)


Gene name ataR Uniprot ID -
Locus tag MC269_RS00690 Protein ID WP_239953387.1
Coordinates 152863..153153 (-) Length 97 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MC269_RS00665 147839..148759 + 921 WP_239953382.1 AraC family transcriptional regulator -
MC269_RS00670 148833..149957 + 1125 WP_239953383.1 GNAT family N-acetyltransferase -
MC269_RS00675 149954..151786 - 1833 WP_239953384.1 ABC transporter ATP-binding protein -
MC269_RS00680 151850..152356 + 507 WP_239953385.1 GNAT family N-acetyltransferase -
MC269_RS00685 152348..152875 - 528 WP_239953386.1 GNAT family N-acetyltransferase Toxin
MC269_RS00690 152863..153153 - 291 WP_239953387.1 DUF1778 domain-containing protein Antitoxin
MC269_RS00695 153356..153547 - 192 WP_239953388.1 hypothetical protein -
MC269_RS00700 153699..155090 + 1392 WP_239953389.1 MFS transporter -
MC269_RS00705 155203..156366 + 1164 WP_239953390.1 HD-GYP domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(82-152)

Antitoxin

Vibrio phage ICP1, Orf50

(9-84)


Sequences

Toxin        


Download         Length: 176 a.a.        Molecular weight: 19214.26 Da        Isoelectric Point: 8.4502

>T235991 WP_239953386.1 NZ_CP092373:c152875-152348 [Pantoea sp. Z09]
MEAVTLKIIRFSPQLPLNSANFSCGRPALDDFLKKHLAAQHQQNVLKAYLLVTDDPVAEVLGYYTLSGGSYARSAMTRTF
QKQAAPYHETACIILSRLAVDKRIAGKGFGTQLVLDALRVAWHAADAVGIYAVMVEAKDEEAAGFYREAMNFIPLKTDDG
KLKFFFPVASIASLL

Download         Length: 528 bp

>T235991 NZ_LR134531:1294027-1294335 [Pragia fontium]
ATGCAATATGCCGTTTATCGTCATGCTGGAAACAGTAAAGATTATCCCTATTTATTGAATATACAGAGCGACTTAATTGG
TGCGCTTAATACTCGGTTAGTCATTCCACTTTTTCCACTAAATCGATTTACAGGAAACAGACCGCAACATCTGTGTCCTG
TACTCCACATTGAAAATAGTGATTTTTTAGTGATGACCCATGAAATGGCCAGCGTAAGACAAACGATGCTTGGTGAAGTT
GTTTGTCACGTTGATCATCACAGGGACGAGATTAAAGCGGCGATTGATTTTTTAATTGATGGCTTTTGA

Antitoxin


Download         Length: 97 a.a.        Molecular weight: 11160.49 Da        Isoelectric Point: 7.2074

>AT235991 WP_239953387.1 NZ_CP092373:c153153-152863 [Pantoea sp. Z09]
MGASAKSERMELRISPHDKQEIEQAAQLSRVSVSQFIADSARERAEQIINEHKRIQLTEASYRAVMEALENPPEPNERLR
RAADLSRKDSTWEWKR

Download         Length: 291 bp

>AT235991 NZ_LR134531:1293782-1294024 [Pragia fontium]
ATGTCAGTAACCCATGCCAAAACAACTAAAAAGACAGTGAGTGTCACTTTAGATCCCGATTTATATCAACGGGCTCGCGA
TATGGGCATTAACCTCTCAGCATTATTAACTCAGGCCGTTGAGCAGCAATTGCAGGCGGCATCAAGGGCTCAGTGGCAAC
GAGATAATCAGCAGGCAATGGAAGAGCTCAATCGTATTACTGAACGGTGTGGGCTGCTCTCTGATGAATATCGAGCGTTT
TAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References