Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/ParE-RHH
Location 235129..235676 Replicon chromosome
Accession NZ_CP092370
Organism Flavobacterium sp. CBA20B-1

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag MG290_RS01130 Protein ID WP_264562096.1
Coordinates 235129..235428 (-) Length 100 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag MG290_RS01135 Protein ID WP_264562097.1
Coordinates 235428..235676 (-) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MG290_RS01110 (MG290_01110) 231096..231860 + 765 WP_264562092.1 peroxide stress protein YaaA -
MG290_RS01115 (MG290_01115) 231954..232232 + 279 WP_264562093.1 hypothetical protein -
MG290_RS01120 (MG290_01120) 232528..232701 - 174 WP_264562094.1 hypothetical protein -
MG290_RS01125 (MG290_01125) 233755..235050 + 1296 WP_264562095.1 group II intron reverse transcriptase/maturase -
MG290_RS01130 (MG290_01130) 235129..235428 - 300 WP_264562096.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
MG290_RS01135 (MG290_01135) 235428..235676 - 249 WP_264562097.1 type II toxin-antitoxin system ParD family antitoxin Antitoxin
MG290_RS01140 (MG290_01140) 236199..236543 - 345 WP_264562098.1 SdpI family protein -
MG290_RS01145 (MG290_01145) 236609..237067 - 459 WP_264562099.1 hypothetical protein -
MG290_RS01150 (MG290_01150) 237069..238424 - 1356 WP_264562100.1 lysophospholipase -
MG290_RS01155 (MG290_01155) 238430..239008 - 579 WP_264562101.1 YIP1 family protein -
MG290_RS01160 (MG290_01160) 239012..239284 - 273 WP_257498579.1 DUF2089 domain-containing protein -
MG290_RS01165 (MG290_01165) 239413..240339 - 927 WP_264562102.1 EamA family transporter -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-92)

Antitoxin

Antitoxin ParD

(4-72)


Sequences

Toxin        


Download         Length: 100 a.a.        Molecular weight: 12113.75 Da        Isoelectric Point: 6.4878

>T235989 WP_264562096.1 NZ_CP092370:c235428-235129 [Flavobacterium sp. CBA20B-1]
MGYKISHEANRDIENIWLYTYENWSLEQADRYINLIIDEIEYLAENPKSGKDYGHLRKGYFRSQIKSHFIFYKISLKREE
IEIIRVLHQRMDIESRLTE

Download         Length: 300 bp

>T235989 NZ_LR134529:c1852631-1852323 [Bartonella vinsonii]
ATGGTAGTTATTCATAAAACTATAGAATTTGATACTTGGCTTAAGAAACTCAAAGATAAAAGCGCTAAAGCTATTATTCT
TCAACGTGTTGTACGATTGAAACAAGGTCTTTTAGGTGATGTTAAATTTTTTCATGGCATAGGTGAATTACGTATTCACT
ATGGTGCTGGTTACAGAGTTTATTTTACCCAAAAAGGCTCTGAGTTTATCCTTTTGTTATGCGGTGGAGATAAATCAACG
CAGAAAAAAGATATTGAACAAGCGTTAAAGTTAAAAGAGGAGTACAGTGATGAAAACTACACCATTTAA

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9558.00 Da        Isoelectric Point: 10.3361

>AT235989 WP_264562097.1 NZ_CP092370:c235676-235428 [Flavobacterium sp. CBA20B-1]
MAKNTSILLGDYFDNFISRQIKTGKYSSASEVVRAALRMFEYEESKRTELIKELKKGEKSGFVKNFDRKELLNSLHQKHL
SK

Download         Length: 249 bp

>AT235989 NZ_LR134529:c1852342-1852061 [Bartonella vinsonii]
ATGAAAACTACACCATTTAAACCAGAGGAATATCTTGAAACCACTGAGGAACAACAAATATTTCTCAATGAAGCCTTCAA
AACTGGTGATGCTGCACATATAGCGGATGCCCTTGGTATCGTTGCTAGAGCCCAAAATATGAGTACTTTAGCAAAAGAAA
CCAATCGCGAACGTAGTGGTTTATATCGCTCCTTAAGTAAAACAGGTGACCCTAAACTTTCTACTTTAGTTGCTGTGCTC
TCTGCCCTTAATTTGCAATTAAGCGTAGAATCTACTTCATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References