Detailed information of TA system TA235944

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): vapBC/VapC-Phd
• Location: 2373562..2374223
• Replicon: chromosome
• Accession: NZ_CP092348
• Organism: Rhizobium sp. C104

Toxin (Protein)

• Gene name: vapB
• Uniprot ID: -
• Locus tag: MF410_RS12950
• Protein ID: WP_097627533.1
• Coordinates: 2373816..2374223 (+)
• Length: 136 a.a.

Antitoxin (Protein)

• Gene name: vapB
• Uniprot ID: -
• Locus tag: MF410_RS12945
• Protein ID: WP_097627535.1
• Coordinates: 2373562..2373816 (+)
• Length: 85 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
MF410_RS12915 (MF410_12920)	2368795..2369460	+	666	WP_097627543.1	glutathione S-transferase family protein	-
MF410_RS12920 (MF410_12925)	2369567..2370463	-	897	WP_097627541.1	LysR substrate-binding domain-containing protein	-
MF410_RS12925 (MF410_12930)	2370577..2370771	+	195	WP_097627539.1	hypothetical protein	-
MF410_RS12930 (MF410_12935)	2370847..2371317	-	471	WP_239619797.1	GNAT family N-acetyltransferase	-
MF410_RS12935 (MF410_12940)	2371713..2372459	+	747	WP_239619798.1	phosphodiester glycosidase family protein	-
MF410_RS12940 (MF410_12945)	2372807..2373457	+	651	WP_097627763.1	glutathione S-transferase family protein	-
MF410_RS12945 (MF410_12950)	2373562..2373816	+	255	WP_097627535.1	type II toxin-antitoxin system Phd/YefM family antitoxin	Antitoxin
MF410_RS12950 (MF410_12955)	2373816..2374223	+	408	WP_097627533.1	type II toxin-antitoxin system VapC family toxin	Toxin
MF410_RS12955 (MF410_12960)	2374269..2374889	-	621	WP_097627531.1	glutathione S-transferase family protein	-
MF410_RS12960 (MF410_12965)	2375175..2375531	-	357	WP_183777452.1	DUF4406 domain-containing protein	-
MF410_RS12965 (MF410_12970)	2375660..2376415	+	756	WP_097627529.1	DeoR/GlpR family DNA-binding transcription regulator	-
MF410_RS12970 (MF410_12975)	2376526..2377314	+	789	WP_097627761.1	carbon-nitrogen hydrolase family protein	-
MF410_RS12975 (MF410_12980)	2377394..2378405	-	1012	Protein_2350	asparaginase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• PIN domain (2-116)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (2-61)

Sequences

Toxin

Protein

• Length: 136 a.a.
• Molecular weight: 14811.03 Da
• Isoelectric Point: 7.4713

>T235944 WP_097627533.1 NZ_CP092348:2373816-2374223 [Rhizobium sp. C104]
MYLVDTNIVSEARRGTSQAISWLRSVDPLSIHLSALTLGEIMRGIALKQRSDPKAAAHLTEWLRKLRHDHGARILPVTDQ
IAVEWGRIAAIRPRGDIDGLIAATAIVHDLIVVTRNVSDFADTGASVINPWEMSA

Nucleotide

• Length: 408 bp

>T235944 NZ_LR134501:c4706454-4706035 [Nocardiopsis dassonvillei]
GTGAACACCGTCTATCTGGTGGACAGCTCCGCCTGGGTGGAGTACCTGCGCAAGACCGGTTCCGAGACCCACGTCTTCGT
CAGGGAACTCATCGAGCGCGGCGTCCACCTGGCCACGACCGAACCCGTCGCCGCCGAGATCCTGAGCGGGGCGAAGAGCT
CCACCGAGCTCCAGCAGCTGGAACGCCTCACCGACGGCCTGATCCAGCTGTCTCTGGACAACAGGCTCGACTTCCACCAT
TCGGCGGGCATCTACCGTGAGGCCCGCTCCAGGGGTAAGACGATCCGCAAGCTCTACGACTGCCTCATCGCGGCCGTCGC
CCTGCGCACCGACGCGGTCCTCGTGCACTGCGACCGCGACTTCGACCACCTCGCCGAGGTGTTCCCCCGGCTGCGCGTGC
AGCGGCACGACCAGGACTGA

Antitoxin

Protein

• Length: 85 a.a.
• Molecular weight: 9284.39 Da
• Isoelectric Point: 4.7872

>AT235944 WP_097627535.1 NZ_CP092348:2373562-2373816 [Rhizobium sp. C104]
MEWQLQEAKNKFSKVVQKARDEGPQVVTLRGERTAVVLSARDYDALRAGRPTLVDDLLGGPAWDDELANTVEARAASPSR
DVTF

Nucleotide

• Length: 255 bp

>AT235944 NZ_LR134501:c4706672-4706451 [Nocardiopsis dassonvillei]
ATGAGTCGCACAAACATTGACATCGACGACGAACTGGTCACTACCGCCATGGAACGCTTCCAGGTGAGCACCAAGCGCGA
AGCCGTGGACATCGCCCTTCGCCGGGCCGTGGGCACACCTCTCACCAAGGAGTTCCTCCTCAGCCTGGAGGGCATCGGCT
GGGAGGGCGACCTGGAAGAGATGCGCCGCTCCGGCTTCGAGGGCGGGGCGCCCGCCTCGTGA