Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/LOTUS_5_Limkain_b1-Phd
Location 815695..816380 Replicon plasmid pRGM101b
Accession NZ_CP092346
Organism Rhizobium gallicum strain M101

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag L2W42_RS27555 Protein ID WP_239602743.1
Coordinates 815695..816117 (-) Length 141 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag L2W42_RS27560 Protein ID WP_239602746.1
Coordinates 816114..816380 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
L2W42_RS27530 (L2W42_27530) 811268..812266 - 999 WP_239602735.1 substrate-binding domain-containing protein -
L2W42_RS27535 (L2W42_27535) 812678..812806 - 129 Protein_795 EamA/RhaT family transporter -
L2W42_RS27540 (L2W42_27540) 812868..813972 - 1105 Protein_796 nucleotidyl transferase AbiEii/AbiGii toxin family protein -
L2W42_RS27545 (L2W42_27545) 813953..814696 - 744 WP_239602738.1 DUF6088 family protein -
L2W42_RS27550 (L2W42_27550) 815012..815542 - 531 WP_239602740.1 hypothetical protein -
L2W42_RS27555 (L2W42_27555) 815695..816117 - 423 WP_239602743.1 type II toxin-antitoxin system VapC family toxin Toxin
L2W42_RS27560 (L2W42_27560) 816114..816380 - 267 WP_239602746.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
L2W42_RS27565 (L2W42_27565) 816586..816750 - 165 Protein_801 nucleotidyl transferase AbiEii/AbiGii toxin family protein -
L2W42_RS27570 (L2W42_27570) 816743..817336 - 594 WP_239602750.1 DUF6088 family protein -
L2W42_RS27575 (L2W42_27575) 817391..817534 + 144 WP_239602753.1 hypothetical protein -
L2W42_RS27580 (L2W42_27580) 817780..817915 - 136 Protein_804 recombinase family protein -
L2W42_RS27585 (L2W42_27585) 818000..819169 - 1170 WP_239602757.1 ATP-binding protein -
L2W42_RS27590 (L2W42_27590) 819315..820220 - 906 WP_239602759.1 EamA family transporter -
L2W42_RS27595 (L2W42_27595) 820761..821012 + 252 WP_239602762.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - htpB 1..2542150 2542150


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-125)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(9-64)


Sequences

Toxin        


Download         Length: 141 a.a.        Molecular weight: 15546.85 Da        Isoelectric Point: 4.6876

>T235939 WP_239602743.1 NZ_CP092346:c816117-815695 [Rhizobium gallicum]
VRLLLDTNVLSEVTKPCPDTRVLEWLDGLDEDRAFISVVSIAEIRRGVALMDSGRKRDALAEWLARDLPQRFEKRVIPVE
EPVALAWGELMALAKRSGRGLSSMDGLIAATAMAHDLTLATRNTRDFEGFGIEIVDPWSS

Download         Length: 423 bp

>T235939 NZ_LR134494:c4684510-4684127 [Serratia quinivorans]
ATGCAAACTTTACCTTTAACCCCGCAACGGGCGGCTTCGTCCTGCCCGTCACCCGTTGAGATATGGCAAAAACTGCTGAC
GCATCTGCTCGAACAACACTATGGTCTGACGCTGAGTGATACTCCATTCAGCAATGAAACCACCATTCGCGAGCATATCG
ACGCTGGGATCTCCCTCAGCGATGCGGTGAACTTTCTGGTGGAGAAGTATGAACTGGTGCGCACTGACCAGCCTGGTTTC
ACCTTAATGGAGCAGTCACCGTTTATCACCCCAATCGATATTCTCCGCGCCAGGCAAGCCACCGGTCTGATGAAGCGCAG
GGGTTATAAAGCTGTGAGTGATATTACCCGTGGCAAAGTGAGTCGGATGGAGCAACACCATTGA

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 9838.11 Da        Isoelectric Point: 7.2053

>AT235939 WP_239602746.1 NZ_CP092346:c816380-816114 [Rhizobium gallicum]
MQPSTHDDKSWTVASAKAKLSEVIERAQSVPQTITRNGKPSVVVVSAEEWHKKTARKGSLAEFLMDSPLRGADLDLERQR
DEPRDLPL

Download         Length: 267 bp

>AT235939 NZ_LR134494:c4684933-4684565 [Serratia quinivorans]
ATGAAATCTGTCGCCTCAGCCGGTATACCACCGGAGGACAATCCGTGCCTGCAATGGGGATTGGATCGCGAAGTTACCCC
CTGCTTTGGTGCGCGTCTGGTGCAGGAAGGCAATCGCCTGCATTTTCTGGCTGACCGTGCGGGATTTAACGGTACATTCA
GTGAGGATGACGCGTTGCGGCTCGACCAGGCATTTCCGCTGATGCTCAAAGAGCTTGAACTCAGGCTGCGCTCAGGTGAG
CTCAATCCTCGCCGTCAGCATTGCGTTACGTTGAACCACAATAGCCTGACCTGCGAAGCCGACACCCTCGGTTCTTACGG
GTATGTTTATATTGCCATTTACCCGATCAACCTGTGCCCATCTGTGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References