Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC(toxin)
Location 592344..592987 Replicon plasmid pRGM101b
Accession NZ_CP092346
Organism Rhizobium gallicum strain M101

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag L2W42_RS26460 Protein ID WP_133939282.1
Coordinates 592344..592730 (-) Length 129 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag L2W42_RS26465 Protein ID WP_239602413.1
Coordinates 592730..592987 (-) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
L2W42_RS26440 (L2W42_26440) 587993..589255 - 1263 WP_239603460.1 plasmid replication protein RepC -
L2W42_RS26445 (L2W42_26445) 589406..590452 - 1047 WP_239602411.1 plasmid partitioning protein RepB -
L2W42_RS26450 (L2W42_26450) 590504..591718 - 1215 WP_040116398.1 plasmid partitioning protein RepA -
L2W42_RS26455 (L2W42_26455) 592026..592360 - 335 Protein_578 hypothetical protein -
L2W42_RS26460 (L2W42_26460) 592344..592730 - 387 WP_133939282.1 type II toxin-antitoxin system VapC family toxin Toxin
L2W42_RS26465 (L2W42_26465) 592730..592987 - 258 WP_239602413.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
L2W42_RS26470 (L2W42_26470) 593044..593223 - 180 WP_239602415.1 hypothetical protein -
L2W42_RS26475 (L2W42_26475) 593391..593957 - 567 WP_194732001.1 TetR/AcrR family transcriptional regulator -
L2W42_RS26480 (L2W42_26480) 594270..594746 + 477 WP_239602417.1 2Fe-2S iron-sulfur cluster-binding protein -
L2W42_RS26485 (L2W42_26485) 594743..595726 + 984 WP_239602419.1 xanthine dehydrogenase family protein subunit M -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - htpB 1..2542150 2542150


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(1-124)

Antitoxin

Antitoxin VapB-like

(1-84)


Sequences

Toxin        


Download         Length: 129 a.a.        Molecular weight: 14019.13 Da        Isoelectric Point: 4.3857

>T235938 WP_133939282.1 NZ_CP092346:c592730-592344 [Rhizobium gallicum]
MVIDTSAIVAILRSEPEAATLERTVVANPIRLVPATCVLETRMVLVSRRGEHALAEIDLWLARIEADIVPVDADLVDLAT
QAWLTYGKGRHPAALNFADCFSYALAKRADEPLLFIGEDFSRTDIEAA

Download         Length: 387 bp

>T235938 NZ_LR134494:c4316074-4315652 [Serratia quinivorans]
GTGGCCCAGTGGCGATGTGACGTCCGTATTTCCTGGCGCACCCAGTTATTTTCGCTGCTGACACATGGCGTATTGATCCT
GCTGATCCTGATTTCGCCCTGGCCGGAAGGCTATGGCCCGATCTGGCTGGTGCTACTGACGCTGGTGGTGTTTGAGTGCA
TTCGCAGCCAAAAGCGTATTGCGTCGCGGCAGGGTGAGCTGCGCCTGCTGGAGAACCAACGCCTGGGTTGGCATGGGCAG
GAGTGGCAACTGCTAAAGCAGCCCTGGATGCCACGTTACGGCATTCTGTTGACCTTACAGCCGGTGGGAGGCAAAAAGCG
CCGTCGGCTGTGGCTGGCTTCCGACTCCATGGCTAAAGCCGACTGGCGGCAGTTGCGCCAACGGTTGCTGTATCCGCCCG
CCAGTGATGACGAGGAGGCCTGA

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9507.79 Da        Isoelectric Point: 6.2219

>AT235938 WP_239602413.1 NZ_CP092346:c592987-592730 [Rhizobium gallicum]
MSLNIKNPATVALVDELARRQGISKTAAIHQALTERLHRMGYGDVAQERLLTEMQAIRGRVARLPELDSRSDEEIIGYDE
HGIPN

Download         Length: 258 bp

>AT235938 NZ_LR134494:c4316321-4316055 [Serratia quinivorans]
ATGGATATTAATAACAAAGCACGTATCCACTGGGCTTGTCGCCGCGGTATGCGTGAGCTGGACATCTCCATCATGCCCTT
CTTCGAGTATGAATATGACCTGTTGAACGATACAGACAAAGCGCTGTTTATCCGTCTGCTGGAGTCTGACGATCCCGATC
TCTTCAATTGGCTGATGAATCATGGCGCTCCGCAGGACAGTGAACTGCAGAGAATGGTGACACTGATCCAGACGCGAAAT
AAAGACCGTGGCCCAGTGGCGATGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References