Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /BrnT(toxin)
Location 4521899..4522406 Replicon chromosome
Accession NZ_CP092289
Organism Marinobacter sp. M1C

Toxin (Protein)


Gene name - Uniprot ID -
Locus tag MIH19_RS21250 Protein ID WP_249006763.1
Coordinates 4522233..4522406 (-) Length 58 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID -
Locus tag MIH19_RS21245 Protein ID WP_249006762.1
Coordinates 4521899..4522153 (-) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MIH19_RS21215 (MIH19_21215) 4517213..4518061 - 849 WP_249006756.1 putative selenate ABC transporter substrate-binding protein -
MIH19_RS21220 (MIH19_21220) 4518341..4518979 - 639 WP_249006757.1 SGNH/GDSL hydrolase family protein -
MIH19_RS21225 (MIH19_21225) 4519370..4519699 - 330 WP_249006758.1 DHCW motif cupin fold protein -
MIH19_RS21230 (MIH19_21230) 4519799..4520062 - 264 WP_249006759.1 Txe/YoeB family addiction module toxin -
MIH19_RS21235 (MIH19_21235) 4520059..4520301 - 243 WP_249006760.1 type II toxin-antitoxin system Phd/YefM family antitoxin -
MIH19_RS21240 (MIH19_21240) 4520541..4521488 - 948 WP_249006761.1 D-hexose-6-phosphate mutarotase -
MIH19_RS21245 (MIH19_21245) 4521899..4522153 - 255 WP_249006762.1 CopG family transcriptional regulator Antitoxin
MIH19_RS21250 (MIH19_21250) 4522233..4522406 - 174 WP_249006763.1 BrnT family toxin Toxin
MIH19_RS21255 (MIH19_21255) 4522536..4522952 - 417 WP_249006764.1 GFA family protein -
MIH19_RS21260 (MIH19_21260) 4523304..4523600 - 297 WP_249006765.1 type II toxin-antitoxin system RelE/ParE family toxin -
MIH19_RS21265 (MIH19_21265) 4523600..4523854 - 255 WP_249006766.1 type II toxin-antitoxin system ParD family antitoxin -
MIH19_RS21270 (MIH19_21270) 4524468..4524950 - 483 WP_249006768.1 SgcJ/EcaC family oxidoreductase -
MIH19_RS21275 (MIH19_21275) 4525066..4525347 - 282 WP_249006769.1 type II toxin-antitoxin system RelE/ParE family toxin -
MIH19_RS21280 (MIH19_21280) 4525344..4525616 - 273 WP_249006770.1 ribbon-helix-helix protein, CopG family -
MIH19_RS21285 (MIH19_21285) 4525820..4526065 + 246 WP_249006771.1 type II toxin-antitoxin system CcdA family antitoxin -
MIH19_RS21290 (MIH19_21290) 4526065..4526382 + 318 WP_072795464.1 CcdB family protein -
MIH19_RS21295 (MIH19_21295) 4526475..4526963 - 489 WP_249006772.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 4519370..4567768 48398


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Ribonuclease toxin, BrnT, of type II toxin-antitoxin system

(6-56)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 58 a.a.        Molecular weight: 6676.57 Da        Isoelectric Point: 5.0495

>T235909 WP_249006763.1 NZ_CP092289:c4522406-4522233 [Marinobacter sp. M1C]
MDEFEFDETKSQTNLDKHGIDFVAARVLWKDPYLLEIRAKSEGEPRFVLIGKIGERH

Download         Length: 174 bp

>T235909 NZ_LR134485:3649833-3650051 [Citrobacter youngae]
ATGTCCGATAAACCATTAACTAAAACAGATTATTTGATGCGCCTGCGACGCTGTCAAACAATTGACACGCTTGAACGTGT
TATTGAGAAAAATAAATATGAATTGTCTGACAATGAACTGGCTGTATTTTACTCAGCCGCCGATCATCGTCTTGCTGAAT
TGACAATGAATAAGCTCTACGACAAGATCCCAACATCTGTTTGGAAATTTATTCGTTAA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9814.09 Da        Isoelectric Point: 5.8726

>AT235909 WP_249006762.1 NZ_CP092289:c4522153-4521899 [Marinobacter sp. M1C]
MKARDFDKKFEEGQDDIVDDLDLSTVRRVNQEQKRINVDFPAWVVESLDREAARIGVTRQSIIKVWLVERLQAESANKCV
TRTH

Download         Length: 255 bp

>AT235909 NZ_LR134485:3649432-3649806 [Citrobacter youngae]
ATGGATGAATACTCACCGAAAAGACATGATATCGCGCAGCTTAAATTTCTCTGCGAAACCCTGTATCATGACTGTCTTGC
AAACCTTGAACAAAGCAATCATGGTTGGGTAAATGACCCTACCTCTGCAACCAGCTTGCAGCTCAATGAACTGATAGAGC
ATATTGCAACCTTCGCACTTAATTATAAAATTAAGTACAATGAGGACAATAAGCTGATCGCGCAGATTGATGAATACCTG
GATGACACTTTTATGTTGTTCAGTAGTTATGGTATTAATACGCAGGATCTACAGAAATGGCGGAAGTCAGGTAATCGACT
GTTTCGCTGTTTTGTCAATGCCACCAGGGCTAATCCTGTCAGTTTGTCTTGTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References